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Category:GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
name: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
namespace: molecular_function
alt_id: GO:0061505
def: "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2." [PMID:8811192]
synonym: "deoxyribonucleate topoisomerase" BROAD [GOC:krc]
synonym: "deoxyribonucleic topoisomerase activity" BROAD [EC:5.6.2.2, GOC:krc]
synonym: "DNA topoisomerase (ATP-hydrolysing)" RELATED [EC:5.6.2.2, GOC:krc]
synonym: "DNA topoisomerase II" NARROW [EC:5.6.2.2, GOC:krc]
synonym: "DNA topoisomerase II activity" NARROW [GOC:krc]
synonym: "DNA topoisomerase IV activity" NARROW [GOC:krc]
synonym: "DNA topoisomerase type II activity" EXACT [GOC:krc]
synonym: "topoisomerase" BROAD [EC:5.6.2.2, GOC:krc]
synonym: "topoisomerase II" NARROW [GOC:krc]
synonym: "type II DNA topoisomerase activity" RELATED [EC:5.6.2.2, GOC:krc]
xref: EC:5.6.2.2
xref: MetaCyc:5.99.1.3-RXN
xref: Wikipedia:Type_II_topoisomerase
is_a: GO:0003916 ! DNA topoisomerase activity
is_a: GO:0008094 ! ATP-dependent activity, acting on DNA
AmiGO
<GOterm>GO:0003918</GOterm>
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This category has the following 5 subcategories, out of 5 total.
Pages in category "GO:0003918 ! DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"
The following 6 pages are in this category, out of 6 total.
