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MOUSE:U17LC

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Usp17lc (ECO:0000312 with MGI:MGI:107698)
Protein Name(s) Ubiquitin carboxyl-terminal hydrolase 17-like protein C (ECO:0000312 with MGI:MGI:107698)

Deubiquitinating enzyme 2 (ECO:0000305 with PMID:8995226[1])

External Links
UniProt G5E8I7
EMBL U70368
U70369
AC162877
CH466531
RefSeq NP_034219.3
UniGene Mm.382906
STRING 10090.ENSMUSP00000078323
MEROPS C19.032
PaxDb G5E8I7
Ensembl ENSMUST00000079348
ENSMUST00000106892
GeneID 13532
KEGG mmu:13532
UCSC uc009itr.1
CTD 13532
MGI MGI:107698
eggNOG KOG1865
ENOG410XQ92
GeneTree ENSGT00890000139343
HOGENOM HOG000144638
HOVERGEN HBG007129
KO K11845
OMA QKHRINE
OrthoDB EOG091G06D5
TreeFam TF315281
Reactome R-MMU-5689880
Proteomes UP000000589
Bgee ENSMUSG00000058976
GO GO:0004843
GO:0016579
GO:0006511
InterPro IPR001394
IPR018200
IPR028889
Pfam PF00443
PROSITE PS00972
PS00973
PS50235

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043009

chordate embryonic development

PMID:22984479[2]

ECO:0000315

P

Table 1 & Figure 4

complete
CACAO 5179

involved_in

GO:0043009

chordate embryonic development

PMID:22984479[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000607281
UniProtKB:Q6R6M4

P

Seeded From UniProt

complete

involved_in

GO:0016579

protein deubiquitination

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0005632
FB:FBgn0016756
FB:FBgn0260936
MGI:MGI:107698
MGI:MGI:107699
MGI:MGI:1270128
MGI:MGI:1916977
MGI:MGI:1919594
MGI:MGI:1924050
MGI:MGI:2182061
MGI:MGI:3051498
MGI:MGI:3643640
PANTHER:PTN002541993
RGD:1306915
SGD:S000000953
SGD:S000001418
SGD:S000002280
SGD:S000004920
SGD:S000005130
SGD:S000005650
TAIR:locus:2083440
TAIR:locus:2121959
UniProtKB:A0A0B4KI06
UniProtKB:O75317
UniProtKB:O94782
UniProtKB:P45974
UniProtKB:P62068
UniProtKB:Q14694
UniProtKB:Q6R6M4
UniProtKB:Q70CQ2
UniProtKB:Q86T82
UniProtKB:Q8NB14
UniProtKB:Q93008
UniProtKB:Q93009
UniProtKB:Q96RU2
UniProtKB:Q9BXU7
UniProtKB:Q9FPS9
UniProtKB:Q9H9J4
UniProtKB:Q9P275
UniProtKB:Q9P2H5
UniProtKB:Q9UHP3
WB:WBGene00010406
dictyBase:DDB_G0275021

P

Seeded From UniProt

complete

enables

GO:0004843

thiol-dependent ubiquitin-specific protease activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0005632
FB:FBgn0016756
FB:FBgn0030366
FB:FBgn0260936
MGI:MGI:107698
MGI:MGI:107699
MGI:MGI:1924050
MGI:MGI:2182061
MGI:MGI:3051372
MGI:MGI:3051498
MGI:MGI:3643640
PANTHER:PTN002541993
PomBase:SPBP8B7.21
RGD:1306915
SGD:S000000163
SGD:S000000262
SGD:S000000953
SGD:S000001418
SGD:S000001806
SGD:S000002280
SGD:S000004920
SGD:S000005130
SGD:S000005650
TAIR:locus:2010622
TAIR:locus:2083440
TAIR:locus:2140074
UniProtKB:O75317
UniProtKB:O94782
UniProtKB:P45974
UniProtKB:P62068
UniProtKB:Q0WX57
UniProtKB:Q14694
UniProtKB:Q6QN14
UniProtKB:Q6R6M4
UniProtKB:Q70CQ2
UniProtKB:Q84WU2
UniProtKB:Q86T82
UniProtKB:Q8LAM0
UniProtKB:Q8NB14
UniProtKB:Q92995
UniProtKB:Q93009
UniProtKB:Q96K76
UniProtKB:Q96RU2
UniProtKB:Q96V54
UniProtKB:Q9FPS0
UniProtKB:Q9FPS9
UniProtKB:Q9FPT1
UniProtKB:Q9H9J4
UniProtKB:Q9P275
UniProtKB:Q9P2H5
UniProtKB:Q9UHP3
WB:WBGene00010406
WB:WBGene00011216

F

Seeded From UniProt

complete

enables

GO:0004197

cysteine-type endopeptidase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2182061
PANTHER:PTN002541993
UniProtKB:O75317
UniProtKB:Q14694
UniProtKB:Q70CQ2
UniProtKB:Q86T82
UniProtKB:Q92995
UniProtKB:Q93009

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016579

protein deubiquitination

PMID:8995226[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004843

thiol-dependent ubiquitin-specific protease activity

PMID:8995226[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006511

ubiquitin-dependent protein catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018200

P

Seeded From UniProt

complete

involved_in

GO:0016579

protein deubiquitination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001394

P

Seeded From UniProt

complete

enables

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001394
InterPro:IPR018200

F

Seeded From UniProt

complete

enables

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.4.19.12

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0788

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256
UniProtKB-SubCell:SL-0095

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Zhu, Y et al. (1997) DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. J. Biol. Chem. 272 51-7 PubMed GONUTS page
  2. 2.0 2.1 Baek, KH et al. (2012) Embryonic demise caused by targeted disruption of a cysteine protease Dub-2. PLoS ONE 7 e44223 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page