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MOUSE:TLE6
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tle6 (synonyms: Grg6) | |
| Protein Name(s) | Transducin-like enhancer protein 6
Groucho-related protein 6 | |
| External Links | ||
| UniProt | Q9WVB3 | |
| EMBL | AF145957 | |
| CCDS | CCDS24064.1 | |
| RefSeq | NP_444484.1 | |
| UniGene | Mm.206764 | |
| ProteinModelPortal | Q9WVB3 | |
| SMR | Q9WVB3 | |
| BioGrid | 227763 | |
| IntAct | Q9WVB3 | |
| PhosphoSite | Q9WVB3 | |
| MaxQB | Q9WVB3 | |
| PRIDE | Q9WVB3 | |
| Ensembl | ENSMUST00000072020 | |
| GeneID | 114606 | |
| KEGG | mmu:114606 | |
| UCSC | uc007giu.1 | |
| CTD | 79816 | |
| MGI | MGI:2149593 | |
| eggNOG | NOG276481 | |
| GeneTree | ENSGT00550000074465 | |
| HOGENOM | HOG000154599 | |
| HOVERGEN | HBG014064 | |
| InParanoid | Q9WVB3 | |
| OMA | TEDWLLL | |
| PhylomeDB | Q9WVB3 | |
| TreeFam | TF314167 | |
| NextBio | 368559 | |
| PRO | PR:Q9WVB3 | |
| Proteomes | UP000000589 | |
| Bgee | Q9WVB3 | |
| ExpressionAtlas | Q9WVB3 | |
| Genevestigator | Q9WVB3 | |
| GO | GO:0005938 GO:0005634 GO:0043234 GO:0050769 GO:0045666 | |
| Gene3D | 2.130.10.10 | |
| InterPro | IPR015943 IPR001680 IPR017986 | |
| SMART | SM00320 | |
| SUPFAM | SSF50978 | |
| PROSITE | PS00678 PS50082 PS50294 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0090090 |
negative regulation of canonical Wnt signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001139 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070491 |
repressing transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001139 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104636 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104636 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0001139 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0060136 |
embryonic process involved in female pregnancy |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0050769 |
positive regulation of neurogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0045666 |
positive regulation of neuron differentiation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1347464 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005938 |
cell cortex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000365) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005938 |
cell cortex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
NCBI_Gene:103233664 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0003714 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Marçal, N et al. (2005) Antagonistic effects of Grg6 and Groucho/TLE on the transcription repression activity of brain factor 1/FoxG1 and cortical neuron differentiation. Mol. Cell. Biol. 25 10916-29 PubMed GONUTS page
- ↑ Herr, JC et al. (2008) Distribution of RNA binding protein MOEP19 in the oocyte cortex and early embryo indicates pre-patterning related to blastomere polarity and trophectoderm specification. Dev. Biol. 314 300-16 PubMed GONUTS page
- ↑ Zheng, P & Dean, J (2009) Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis. Proc. Natl. Acad. Sci. U.S.A. 106 7473-8 PubMed GONUTS page
- ↑ Li, L et al. (2008) A subcortical maternal complex essential for preimplantation mouse embryogenesis. Dev. Cell 15 416-25 PubMed GONUTS page
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