MOUSE:TAF4B

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Taf4b (synonyms: Taf2c2, Tafii105)
Protein Name(s)	Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID 105 kDa subunit TAF(II)105 TAFII-105 TAFII105
External Links
UniProt	G5E8Z2
EMBL	AC102692 AC125091 AC133172 CH466622
CCDS	CCDS50227.1
RefSeq	NP_001093919.1
UniGene	Mm.312233
ProteinModelPortal	G5E8Z2
SMR	G5E8Z2
STRING	10090.ENSMUSP00000126909
iPTMnet	G5E8Z2
PaxDb	G5E8Z2
PRIDE	G5E8Z2
Ensembl	ENSMUST00000169862
GeneID	72504
KEGG	mmu:72504
UCSC	uc008edl.2
CTD	6875
MGI	MGI:2152345
eggNOG	KOG2341 ENOG410XQS6
GeneTree	ENSGT00390000011620
KO	K03129
OMA	HEDAKIE
OrthoDB	EOG7327N5
TreeFam	TF316520
Reactome	[www.reactome.org/content/detail/R-MMU-674695 R-MMU-674695] [www.reactome.org/content/detail/R-MMU-6804756 R-MMU-6804756] [www.reactome.org/content/detail/R-MMU-73776 R-MMU-73776] [www.reactome.org/content/detail/R-MMU-73779 R-MMU-73779] [www.reactome.org/content/detail/R-MMU-75953 R-MMU-75953] [www.reactome.org/content/detail/R-MMU-76042 R-MMU-76042]
PRO	PR:G5E8Z2
Proteomes	UP000000589
Genevisible	G5E8Z2
GO	GO:0005737 GO:0005730 GO:0005654 GO:0005667 GO:0005669 GO:0003677 GO:0051059 GO:0003700 GO:0006352 GO:0048477 GO:2000648 GO:0006357 GO:0007283 GO:0006366
Gene3D	1.10.20.10
InterPro	IPR009072 IPR007900 IPR003894
Pfam	PF05236 PF07531
SMART	SM00549
SUPFAM	SSF47113
PROSITE	PS51119

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:2000648	positive regulation of stem cell proliferation	PMID:23350932	ECO:0000315			P		Figure 5 shows transfected mouse embryo cells with TAF4b silenced by siRNAs. Those with silenced TAF4b had lower rates of embryonic cell growth when compared to control.	complete CACAO 9728
involved_in	GO:2000648	positive regulation of stem cell proliferation	PMID:23350932	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010280 PANTHER:PTN000388601 WB:WBGene00006385	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010280 PANTHER:PTN000388601	F		Seeded From UniProt	complete
part_of	GO:0005669	transcription factor TFIID complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010280 PANTHER:PTN000388601 SGD:S000004607 UniProtKB:O00268	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010280 MGI:MGI:2152346 PANTHER:PTN000388601 UniProtKB:O00268 UniProtKB:Q92750	F		Seeded From UniProt	complete
enables	GO:0051059	NF-kappaB binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q92750	F		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q92750	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q92750	F		Seeded From UniProt	complete
part_of	GO:0001650	fibrillar center	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q92750	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003894 InterPro:IPR037249	F		Seeded From UniProt	complete
part_of	GO:0005669	transcription factor TFIID complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007900	C		Seeded From UniProt	complete
involved_in	GO:0006352	DNA-templated transcription, initiation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007900	P		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003894 InterPro:IPR037249	P		Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009072	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006366	transcription by RNA polymerase II	PMID:11557891	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006357	regulation of transcription by RNA polymerase II	PMID:11557891	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:11557891	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0744	P		Seeded From UniProt	complete
involved_in	GO:0048477	oogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0896	P		Seeded From UniProt	complete
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References

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