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MOUSE:SWI5

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Swi5 (synonyms: Sae3)
Protein Name(s) DNA repair protein SWI5 homolog

Protein SAE3 homolog

External Links
UniProt Q8K3D3
EMBL AB597964
AK013517
AK166608
AL808027
AL808027
CH466542
BC021748
CCDS CCDS50566.1
CCDS71026.1
RefSeq NP_001277481.1
NP_780399.1
UniGene Mm.27344
ProteinModelPortal Q8K3D3
SMR Q8K3D3
BioGrid 215652
IntAct Q8K3D3
MINT MINT-4117670
STRING 10090.ENSMUSP00000109027
PhosphoSite Q8K3D3
MaxQB Q8K3D3
PaxDb Q8K3D3
PRIDE Q8K3D3
DNASU 72931
Ensembl ENSMUST00000113395
ENSMUST00000113400
ENSMUST00000183946
GeneID 72931
KEGG mmu:72931
UCSC uc008jet.2
uc012bts.1
CTD 375757
MGI MGI:1920181
eggNOG NOG329079
GeneTree ENSGT00390000009349
HOGENOM HOG000231682
HOVERGEN HBG060201
InParanoid Q8K3D3
OrthoDB EOG79W98D
PhylomeDB Q8K3D3
TreeFam TF336078
NextBio 337161
PRO PR:Q8K3D3
Proteomes UP000000589
Bgee Q8K3D3
CleanEx MM_2900010J23RIK
ExpressionAtlas Q8K3D3
Genevestigator Q8K3D3
GO GO:0005634
GO:0032798
GO:0071479
GO:0000724
InterPro IPR010760
Pfam PF07061

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000730

DNA recombinase assembly

PMID:22492707[1]

ECO:0000270

P

Fig. 2 shows that the SWI5-SFR1 complex functions in stabilization of the Rad51 filament

complete
CACAO 4867

involved_in

GO:0071479

cellular response to ionizing radiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q1ZZU3

P

Seeded From UniProt

complete

part_of

GO:0032798

Swi5-Sfr1 complex

PMID:20976249[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:20976249[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:20976249[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071479

cellular response to ionizing radiation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002003775
UniProtKB:Q1ZZU3

P

Seeded From UniProt

complete

part_of

GO:0032798

Swi5-Sfr1 complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1920181
PANTHER:PTN002003775
PomBase:SPBC409.03
UniProtKB:Q1ZZU3

C

Seeded From UniProt

complete

involved_in

GO:0000730

DNA recombinase assembly

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002003775
PomBase:SPBC409.03

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071479

cellular response to ionizing radiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q1ZZU3

P

Seeded From UniProt

complete

part_of

GO:0032798

Swi5-Sfr1 complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q1ZZU3

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0000724

double-strand break repair via homologous recombination

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q1ZZU3

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Tsai, SP et al. (2012) Rad51 presynaptic filament stabilization function of the mouse Swi5-Sfr1 heterodimeric complex. Nucleic Acids Res. 40 6558-69 PubMed GONUTS page
  2. 2.0 2.1 2.2 Akamatsu, Y & Jasin, M (2010) Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet. 6 e1001160 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page