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MOUSE:STK24

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Stk24 (synonyms: Mst3, Stk3)
Protein Name(s) Serine/threonine-protein kinase 24

Mammalian STE20-like protein kinase 3 MST-3 STE20-like kinase MST3 Serine/threonine-protein kinase 24 35 kDa subunit Mammalian STE20-like protein kinase 3 N-terminal MST3/N Serine/threonine-protein kinase 24 12 kDa subunit Mammalian STE20-like protein kinase 3 C-terminal MST3/C

External Links
UniProt Q99KH8
EMBL BC004650
CCDS CCDS37016.1
RefSeq NP_663440.1
UniGene Mm.390756
Mm.442081
Mm.472866
ProteinModelPortal Q99KH8
SMR Q99KH8
BioGrid 230135
IntAct Q99KH8
MINT MINT-4135908
STRING 10090.ENSMUSP00000078746
iPTMnet Q99KH8
PhosphoSitePlus Q99KH8
EPD Q99KH8
MaxQB Q99KH8
PaxDb Q99KH8
PRIDE Q99KH8
Ensembl ENSMUST00000079817
GeneID 223255
KEGG mmu:223255
UCSC uc007vac.1
CTD 8428
MGI MGI:2385007
eggNOG KOG0201
ENOG410XP9G
GeneTree ENSGT00810000125395
HOGENOM HOG000234203
HOVERGEN HBG108518
InParanoid Q99KH8
KO K08838
OMA DTDGQAS
OrthoDB EOG091G0F24
PhylomeDB Q99KH8
TreeFam TF354217
Reactome [www.reactome.org/content/detail/R-MMU-75153 R-MMU-75153]
ChiTaRS Stk24
PRO PR:Q99KH8
Proteomes UP000000589
Bgee ENSMUSG00000063410
CleanEx MM_STK24
ExpressionAtlas Q99KH8
Genevisible Q99KH8
GO GO:0005737
GO:0005829
GO:0070062
GO:0016020
GO:0005730
GO:0005634
GO:0005524
GO:0045296
GO:0008349
GO:0046872
GO:0004674
GO:0009267
GO:0097194
GO:0008631
GO:0030336
GO:0048812
GO:0046777
GO:0006468
GO:0042981
GO:0048679
GO:0007346
GO:0042542
GO:0031098
InterPro IPR011009
IPR000719
IPR017441
Pfam PF00069
SMART SM00220
SUPFAM SSF56112
PROSITE PS00107
PS50011

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0009267

cellular response to starvation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

involved_in

GO:0030336

negative regulation of cell migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

involved_in

GO:0008631

intrinsic apoptotic signaling pathway in response to oxidative stress

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Y6E0

F

Seeded From UniProt

complete

involved_in

GO:0048812

neuron projection morphogenesis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000685430
WB:WBGene00003247

P

Seeded From UniProt

complete

involved_in

GO:0032147

activation of protein kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919399
PANTHER:PTN000684825
RGD:727905
UniProtKB:Q7RTN6
UniProtKB:Q9C0K7

P

Seeded From UniProt

complete

involved_in

GO:0031098

stress-activated protein kinase signaling cascade

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000684825
UniProtKB:A0A1D8PKE2
UniProtKB:A0A1D8PM87

P

Seeded From UniProt

complete

involved_in

GO:0023014

signal transduction by protein phosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000684825
TAIR:locus:2205523
UniProtKB:Q9UEW8

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0023083
FB:FBgn0025743
FB:FBgn0267698
MGI:MGI:1339975
MGI:MGI:1344404
MGI:MGI:1346867
MGI:MGI:1346875
MGI:MGI:1891638
MGI:MGI:1928487
MGI:MGI:1929004
PANTHER:PTN000684825
PomBase:SPAC1F3.02c
PomBase:SPBC17F3.02
PomBase:SPBC1D7.05
PomBase:SPBC409.07c
PomBase:SPBC543.07
RGD:3780
RGD:620966
RGD:621643
SGD:S000000999
SGD:S000002318
SGD:S000002931
SGD:S000003664
SGD:S000004354
SGD:S000005757
SGD:S000006061
TAIR:locus:2017662
TAIR:locus:2074835
TAIR:locus:2087130
TAIR:locus:2170578
UniProtKB:A0A0B4KGS4
UniProtKB:O00506
UniProtKB:O95819
UniProtKB:Q13043
UniProtKB:Q13153
UniProtKB:Q13177
UniProtKB:Q13188
UniProtKB:Q57Y61
UniProtKB:Q7RTN6
UniProtKB:Q8N4C8
UniProtKB:Q96PY6
UniProtKB:Q9C0K7
UniProtKB:Q9H2G2
UniProtKB:Q9P289
UniProtKB:Q9S7U9
UniProtKB:Q9UKE5
UniProtKB:Q9Y4K4
UniProtKB:Q9Y6E0
UniProtKB:Q9Y6R4
WB:WBGene00002177
WB:WBGene00002201
WB:WBGene00003368
WB:WBGene00013355
dictyBase:DDB_G0284181
dictyBase:DDB_G0286359

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0023083
FB:FBgn0025743
FB:FBgn0031030
FB:FBgn0035001
FB:FBgn0261456
FB:FBgn0267698
MGI:MGI:1344404
MGI:MGI:1346882
MGI:MGI:1349394
MGI:MGI:1355329
MGI:MGI:1858416
MGI:MGI:1917378
MGI:MGI:1920334
PANTHER:PTN000684825
PomBase:SPBC1604.14c
PomBase:SPBC21.06c
RGD:3250
RGD:3251
RGD:621643
RGD:708455
RGD:727905
SGD:S000005242
TAIR:locus:2035989
TAIR:locus:2045658
TAIR:locus:2080394
TAIR:locus:2116417
TAIR:locus:2133559
TAIR:locus:2174969
TAIR:locus:2205523
TAIR:locus:2206885
UniProtKB:A0A0B4KGS4
UniProtKB:C0H4N8
UniProtKB:O75914
UniProtKB:O94804
UniProtKB:O95747
UniProtKB:O95819
UniProtKB:O96013
UniProtKB:Q02750
UniProtKB:Q12851
UniProtKB:Q13043
UniProtKB:Q13153
UniProtKB:Q13177
UniProtKB:Q13188
UniProtKB:Q13233
UniProtKB:Q8IVH8
UniProtKB:Q8N4C8
UniProtKB:Q92918
UniProtKB:Q99558
UniProtKB:Q9H2G2
UniProtKB:Q9H2K8
UniProtKB:Q9UEW8
UniProtKB:Q9UKE5
UniProtKB:Q9UL54
UniProtKB:Q9Y4K4
UniProtKB:Q9Y6E0
WB:WBGene00013355
WB:WBGene00017472
dictyBase:DDB_G0276459
dictyBase:DDB_G0286359

F

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000198103
PANTHER:PTN000685430

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0097194

execution phase of apoptosis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048680

positive regulation of axon regeneration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1561742

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048679

regulation of axon regeneration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046777

protein autophosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042542

response to hydrogen peroxide

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030336

negative regulation of cell migration

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0009267

cellular response to starvation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008631

intrinsic apoptotic signaling pathway in response to oxidative stress

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006468

protein phosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9Y6E0

F

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1561742

C

Seeded From UniProt

complete

involved_in

GO:0097194

execution phase of apoptosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0048679

regulation of axon regeneration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0042542

response to hydrogen peroxide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0030336

negative regulation of cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0009267

cellular response to starvation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0008631

intrinsic apoptotic signaling pathway in response to oxidative stress

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9Y6E0
ensembl:ENSP00000365730

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719

P

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page