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MOUSE:SRRT

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Srrt (synonyms: Ars2, Asr2)
Protein Name(s) Serrate RNA effector molecule homolog

Arsenite-resistance protein 2

External Links
UniProt Q99MR6
EMBL AF312033
AF312033
AF312033
AF312033
BC019117
BC066831
AK150310
CCDS CCDS39331.1
RefSeq NP_001103379.1
NP_001103380.1
NP_113582.1
XP_006504692.1
UniGene Mm.387734
ProteinModelPortal Q99MR6
SMR Q99MR6
BioGrid 219965
IntAct Q99MR6
MINT MINT-1853620
PhosphoSite Q99MR6
MaxQB Q99MR6
PaxDb Q99MR6
PRIDE Q99MR6
Ensembl ENSMUST00000040873
GeneID 83701
KEGG mmu:83701
UCSC uc009acb.2
uc009acc.2
uc012eew.1
CTD 51593
MGI MGI:1933527
eggNOG NOG283007
GeneTree ENSGT00390000005492
InParanoid Q99MR6
OMA DDHGGDP
OrthoDB EOG70PBXD
PhylomeDB Q99MR6
TreeFam TF317609
ChiTaRS Srrt
NextBio 350735
PRO PR:Q99MR6
Proteomes UP000000589
Bgee Q99MR6
CleanEx MM_ARS2
Genevestigator Q99MR6
GO GO:0005737
GO:0005654
GO:0003677
GO:0044822
GO:0008283
GO:0097150
GO:0031053
GO:0006355
GO:0006351
InterPro IPR007042
IPR021933
Pfam PF04959
PF12066

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050769

positive regulation of neurogenesis

PMID:22198669[1]

ECO:0000315

P

Figure 2 demontrates Ars2 regulation of neurogenesis

complete
CACAO 5209

involved_in

GO:0050769

positive regulation of neurogenesis

PMID:22198669[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0097150

neuronal stem cell population maintenance

PMID:22198669[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031053

primary miRNA processing

PMID:19632182[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008283

cell population proliferation

PMID:19632182[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:22198669[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:19632182[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:19632182[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:22198669[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BXP5

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031053

primary miRNA processing

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BXP5

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BXP5

C

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXP5
ensembl:ENSP00000480421

C

Seeded From UniProt

complete

involved_in

GO:0031053

primary miRNA processing

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXP5
ensembl:ENSP00000480421

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BXP5
ensembl:ENSP00000480421

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR035979

F

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039727

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0190

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Andreu-Agullo, C et al. (2012) Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2. Nature 481 195-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gruber, JJ et al. (2009) Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell 138 328-39 PubMed GONUTS page