GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:SODC
Contents
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0050728 |
negative regulation of inflammatory response |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
RNAcentral:URS0000021B51_10090 |
P |
occurs_in:(CL:0000576) |
Seeded From UniProt |
complete | |
involved_in |
GO:0050766 |
positive regulation of phagocytosis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
RNAcentral:URS0000021B51_10090 |
P |
has_agent:(CL:0000129) |
Seeded From UniProt |
complete | |
part_of |
GO:0005615 |
extracellular space |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
produced_by:(CL:0002548) |
Seeded From UniProt |
complete | ||
part_of |
GO:0043209 |
myelin sheath |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000128) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008090 |
retrograde axonal transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008089 |
anterograde axonal transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0072593 |
reactive oxygen species metabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051881 |
regulation of mitochondrial membrane potential |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0051087 |
chaperone binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045859 |
regulation of protein kinase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045541 |
negative regulation of cholesterol biosynthetic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043085 |
positive regulation of catalytic activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0032839 |
dendrite cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0030346 |
protein phosphatase 2B binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010033 |
response to organic substance |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008270 |
zinc ion binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0005886 |
plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005615 |
extracellular space |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005507 |
copper ion binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001819 |
positive regulation of cytokine production |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019430 |
removal of superoxide radicals |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033631 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002467128 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002558032 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002467128 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005507 |
copper ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13419 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13419 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1902177 |
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0072593 |
reactive oxygen species metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0060088 |
auditory receptor cell stereocilium organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0060088 |
auditory receptor cell stereocilium organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0060087 |
relaxation of vascular smooth muscle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
occurs_in:(EMAPA:17312) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0060087 |
relaxation of vascular smooth muscle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
occurs_in:(EMAPA:18609) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0060052 |
neurofilament cytoskeleton organization |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:97313 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0060052 |
neurofilament cytoskeleton organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3574016 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0060047 |
heart contraction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387861 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0060047 |
heart contraction |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0051881 |
regulation of mitochondrial membrane potential |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0051087 |
chaperone binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0050665 |
hydrogen peroxide biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0050665 |
hydrogen peroxide biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0050665 |
hydrogen peroxide biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0048678 |
response to axon injury |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0048365 |
Rac GTPase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0046716 |
muscle cell cellular homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2680903 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0046688 |
response to copper ion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0045859 |
regulation of protein kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0045541 |
negative regulation of cholesterol biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0045471 |
response to ethanol |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043524 |
negative regulation of neuron apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043087 |
regulation of GTPase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0043085 |
positive regulation of catalytic activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0043085 |
positive regulation of catalytic activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0042554 |
superoxide anion generation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0042542 |
response to hydrogen peroxide |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
has_participant:(EMAPA:17838) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0042493 |
response to drug |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
P |
|
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0040014 |
regulation of multicellular organism growth |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0032930 |
positive regulation of superoxide anion generation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0032839 |
dendrite cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0032287 |
peripheral nervous system myelin maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0031667 |
response to nutrient levels |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031045 |
dense core granule |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0030346 |
protein phosphatase 2B binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0030346 |
protein phosphatase 2B binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0030141 |
secretory granule |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019899 |
enzyme binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:95480 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387861 |
P |
has_participant:(EMAPA:16105) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0019226 |
transmission of nerve impulse |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0010033 |
response to organic substance |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0009408 |
response to heat |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008270 |
zinc ion binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0008217 |
regulation of blood pressure |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007626 |
locomotory behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007569 |
cell aging |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007568 |
aging |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007566 |
embryo implantation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007283 |
spermatogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2680903 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006979 |
response to oxidative stress |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
occurs_in:(EMAPA:16846) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0006801 |
superoxide metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006801 |
superoxide metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006801 |
superoxide metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006749 |
glutathione metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
occurs_in:(EMAPA:16846) |
Seeded From UniProt |
complete | |
colocalizes_with |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005777 |
peroxisome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005777 |
peroxisome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005764 |
lysosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005758 |
mitochondrial intermembrane space |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16846)|part_of:(EMAPA:16894)|part_of:(EMAPA:17373)|part_of:(EMAPA:16105) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005615 |
extracellular space |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005507 |
copper ion binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005507 |
copper ion binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2680903 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387861 |
F |
occurs_in:(EMAPA:16105) |
Seeded From UniProt |
complete | |
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
F |
occurs_in:(EMAPA:16332) |
Seeded From UniProt |
complete | |
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3731 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0002262 |
myeloid cell homeostasis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:95480 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0002262 |
myeloid cell homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857872 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001895 |
retina homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001819 |
positive regulation of cytokine production |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0001541 |
ovarian follicle development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
results_in_development_of:(EMAPA:17962) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0000303 |
response to superoxide |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000303 |
response to superoxide |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3526701 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000303 |
response to superoxide |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2680903 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000303 |
response to superoxide |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0000302 |
response to reactive oxygen species |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857873 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000187 |
activation of MAPK activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:1904115 |
axon cytoplasm |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008089 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902177 |
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0072593 |
reactive oxygen species metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060047 |
heart contraction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051881 |
regulation of mitochondrial membrane potential |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0051087 |
chaperone binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050665 |
hydrogen peroxide biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0048365 |
Rac GTPase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045859 |
regulation of protein kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045541 |
negative regulation of cholesterol biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043087 |
regulation of GTPase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043085 |
positive regulation of catalytic activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032930 |
positive regulation of superoxide anion generation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0032839 |
dendrite cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0030346 |
protein phosphatase 2B binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010033 |
response to organic substance |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008270 |
zinc ion binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007569 |
cell aging |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006801 |
superoxide metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005777 |
peroxisome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005507 |
copper ion binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001819 |
positive regulation of cytokine production |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000303 |
response to superoxide |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P00441 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097332 |
response to antipsychotic drug |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071318 |
cellular response to ATP |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071276 |
cellular response to cadmium ion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050665 |
hydrogen peroxide biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0046688 |
response to copper ion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043085 |
positive regulation of catalytic activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035865 |
cellular response to potassium ion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034599 |
cellular response to oxidative stress |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034465 |
response to carbon monoxide |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031667 |
response to nutrient levels |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0031045 |
dense core granule |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0030346 |
protein phosphatase 2B binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0030141 |
secretory granule |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019899 |
enzyme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0019430 |
removal of superoxide radicals |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006801 |
superoxide metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005777 |
peroxisome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005764 |
lysosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005758 |
mitochondrial intermembrane space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005576 |
extracellular region |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005507 |
copper ion binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001975 |
response to amphetamine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P07632 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:V9HWC9 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:V9HWC9 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006801 |
superoxide metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005758 |
mitochondrial intermembrane space |
Reactome:R-MMU-3780963 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0019430 |
removal of superoxide radicals |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004784 |
superoxide dismutase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016209 |
antioxidant activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Butovsky, O et al. (2015) Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice. Ann. Neurol. 77 75-99 PubMed GONUTS page
- ↑ Abonnenc, M et al. (2013) Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ. Res. 113 1138-47 PubMed GONUTS page
- ↑ Werner, HB et al. (2007) Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J. Neurosci. 27 7717-30 PubMed GONUTS page
- ↑ 4.0 4.1 Shi, P et al. (2010) Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport. Biochim. Biophys. Acta 1802 707-16 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ McFadden, SL et al. () Age-related cochlear hair cell loss is enhanced in mice lacking copper/zinc superoxide dismutase. Neurobiol. Aging 20 1-8 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 McFadden, SL et al. (1999) Cu/Zn SOD deficiency potentiates hearing loss and cochlear pathology in aged 129,CD-1 mice. J. Comp. Neurol. 413 101-12 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Morikawa, K et al. (2003) Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J. Clin. Invest. 112 1871-9 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Didion, SP et al. (2002) Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ. Res. 91 938-44 PubMed GONUTS page
- ↑ 10.0 10.1 Nguyen, MD et al. (2001) Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron 30 135-47 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Yoshida, T et al. (2000) Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury. Circ. Res. 86 264-9 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Reaume, AG et al. (1996) Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat. Genet. 13 43-7 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Muller, FL et al. (2006) Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic. Biol. Med. 40 1993-2004 PubMed GONUTS page
- ↑ 14.0 14.1 Kessova, IG & Cederbaum, AI (2007) Mitochondrial alterations in livers of Sod1-/- mice fed alcohol. Free Radic. Biol. Med. 42 1470-80 PubMed GONUTS page
- ↑ 15.0 15.1 Ishii, T et al. (2005) Accelerated impairment of spermatogenic cells in SOD1-knockout mice under heat stress. Free Radic. Res. 39 697-705 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 16.3 Noshita, N et al. (2002) Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice. J. Neurosci. 22 7923-30 PubMed GONUTS page
- ↑ 17.0 17.1 Muller, FL et al. (2004) Complex III releases superoxide to both sides of the inner mitochondrial membrane. J. Biol. Chem. 279 49064-73 PubMed GONUTS page
- ↑ Reddy, VN et al. (2004) Effects of variation in superoxide dismutases (SOD) on oxidative stress and apoptosis in lens epithelium. Exp. Eye Res. 79 859-68 PubMed GONUTS page
- ↑ Lei, XG et al. (2006) Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity. Biochem. J. 399 455-61 PubMed GONUTS page
- ↑ 20.0 20.1 20.2 20.3 Sentman, ML et al. (2006) Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase. J. Biol. Chem. 281 6904-9 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 Flood, DG et al. (1999) Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions. Am. J. Pathol. 155 663-72 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 22.3 Hadjur, S et al. (2001) Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. Blood 98 1003-11 PubMed GONUTS page
- ↑ 23.0 23.1 23.2 Ho, YS et al. (1998) The nature of antioxidant defense mechanisms: a lesson from transgenic studies. Environ. Health Perspect. 106 Suppl 5 1219-28 PubMed GONUTS page
- ↑ 24.0 24.1 24.2 24.3 Ho, YS et al. (1998) Reduced fertility in female mice lacking copper-zinc superoxide dismutase. J. Biol. Chem. 273 7765-9 PubMed GONUTS page
- ↑ 25.0 25.1 Kawase, M et al. (1999) Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency. Stroke 30 1962-8 PubMed GONUTS page
- ↑ 26.0 26.1 26.2 Ohlemiller, KK et al. () Targeted deletion of the cytosolic Cu/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss. Audiol. Neurootol. 4 237-46 PubMed GONUTS page
- ↑ Schmidt-Ott, KM et al. (2006) c-kit delineates a distinct domain of progenitors in the developing kidney. Dev. Biol. 299 238-49 PubMed GONUTS page
- ↑ Keithley, EM et al. (2005) Cu/Zn superoxide dismutase and age-related hearing loss. Hear. Res. 209 76-85 PubMed GONUTS page
- ↑ 29.0 29.1 Iuchi, Y et al. (2007) Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production. Biochem. J. 402 219-27 PubMed GONUTS page
- ↑ 30.0 30.1 Levy, MA et al. (2001) Cellular response of antioxidant metalloproteins in Cu/Zn SOD transgenic mice exposed to hyperoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 281 L172-82 PubMed GONUTS page
- ↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
- ↑ Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page
- ↑ Maggi, LB Jr et al. (2008) Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. Mol. Cell. Biol. 28 7050-65 PubMed GONUTS page
- ↑ Turner, BJ et al. (2005) Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis. J. Neurosci. 25 108-17 PubMed GONUTS page
- ↑ Schäfer, R et al. (1980) Assignment of the gene for cytoplasmic glutamate-oxaloacetate transaminase to mouse chromosome 19 using chinese hamster x mouse somatic cell hybrids. Somatic Cell Genet. 6 709-17 PubMed GONUTS page
- ↑ Francke, U & Taggart, RT (1979) Assignment of the gene for cytoplasmic superoxide dismutase (Sod-1) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse. Proc. Natl. Acad. Sci. U.S.A. 76 5230-3 PubMed GONUTS page
- ↑ Prohaska, JR et al. (2003) Copper, zinc-superoxide dismutase protein but not mRNA is lower in copper-deficient mice and mice lacking the copper chaperone for superoxide dismutase. Exp. Biol. Med. (Maywood) 228 959-66 PubMed GONUTS page
- ↑ Khan, JY & Black, SM (2003) Developmental changes in murine brain antioxidant enzymes. Pediatr. Res. 54 77-82 PubMed GONUTS page
- ↑ Imamura, Y et al. (2006) Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration. Proc. Natl. Acad. Sci. U.S.A. 103 11282-7 PubMed GONUTS page
- ↑ Matzuk, MM et al. (1998) Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology 139 4008-11 PubMed GONUTS page
- ↑ Busuttil, RA et al. (2005) Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice. Cancer Res. 65 11271-5 PubMed GONUTS page
- ↑ 42.0 42.1 42.2 Behndig, A et al. (2001) In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutase. Free Radic. Biol. Med. 31 738-44 PubMed GONUTS page
a
c
- GO:0035865 ! cellular response to potassium ion
- GO:0071318 ! cellular response to ATP
- GO:0071276 ! cellular response to cadmium ion
- GO:0034599 ! cellular response to oxidative stress
- Chordata
- GO:0005507 ! copper ion binding
- Craniata
- GO:0005737 ! cytoplasm
- GO:0031410 ! cytoplasmic vesicle
- GO:0005829 ! cytosol
e
m
n
- GO:0050728 ! negative regulation of inflammatory response
- GO:0045541 ! negative regulation of cholesterol biosynthetic process
- GO:0043524 ! negative regulation of neuron apoptotic process
- GO:0043066 ! negative regulation of apoptotic process
- GO:0060052 ! neurofilament cytoskeleton organization
- GO:0043025 ! neuronal cell body
- GO:0043005 ! neuron projection
- GO:0005654 ! nucleoplasm
- GO:0005634 ! nucleus
o
p
- GO:0032287 ! peripheral nervous system myelin maintenance
- GO:0005777 ! peroxisome
- GO:0005886 ! plasma membrane
- GO:0032930 ! positive regulation of superoxide anion generation
- GO:0043085 ! positive regulation of catalytic activity
- GO:1902177 ! positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
- GO:0001819 ! positive regulation of cytokine production
- GO:0050766 ! positive regulation of phagocytosis
- GO:0032991 ! protein-containing complex
- GO:0051087 ! protein-folding chaperone binding
- GO:0030346 ! protein phosphatase 2B binding
r
- GO:0048365 ! Rac GTPase binding
- GO:0072593 ! reactive oxygen species metabolic process
- GO:0040014 ! regulation of multicellular organism growth
- GO:0043087 ! regulation of GTPase activity
- GO:0008217 ! regulation of blood pressure
- GO:0045859 ! regulation of protein kinase activity
- GO:0051881 ! regulation of mitochondrial membrane potential
- GO:0060087 ! relaxation of vascular associated smooth muscle
- GO:0019430 ! removal of superoxide radicals
- GO:0001975 ! response to amphetamine
- GO:0034465 ! response to carbon monoxide
- GO:0042493 ! response to drug
- GO:0006979 ! response to oxidative stress
- GO:0046688 ! response to copper ion
- GO:0009408 ! response to heat
- GO:0046677 ! response to antibiotic
- GO:0042542 ! response to hydrogen peroxide
- GO:0031667 ! response to nutrient levels
- GO:0045471 ! response to ethanol
- GO:0048678 ! response to axon injury
- GO:0000303 ! response to superoxide
- GO:0000302 ! response to reactive oxygen species
- GO:0097332 ! response to antipsychotic drug
- GO:0001895 ! retina homeostasis
- GO:0008090 ! retrograde axonal transport
- Rodentia
s