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MOUSE:SFR1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Sfr1 (synonyms: Mei5, Meir5)
Protein Name(s) Swi5-dependent recombination DNA repair protein 1 homolog

Meiosis protein 5 homolog

External Links
UniProt Q8BP27
EMBL AK004073
AK011531
AK014266
AK016079
AK077875
AK078147
AK146810
AK167406
AK168068
AK168427
BC024403
CCDS CCDS38019.1
RefSeq NP_080653.2
UniGene Mm.181610
ProteinModelPortal Q8BP27
BioGrid 212442
STRING 10090.ENSMUSP00000096954
PhosphoSite Q8BP27
MaxQB Q8BP27
PaxDb Q8BP27
PRIDE Q8BP27
Ensembl ENSMUST00000099353
GeneID 67788
KEGG mmu:67788
UCSC uc008hvk.1
CTD 119392
MGI MGI:1915038
eggNOG NOG45025
GeneTree ENSGT00390000018550
HOVERGEN HBG056268
InParanoid Q8BP27
OMA QPRENPP
OrthoDB EOG7NSB4P
PhylomeDB Q8BP27
TreeFam TF332725
NextBio 325563
PRO PR:Q8BP27
Proteomes UP000000589
Bgee Q8BP27
CleanEx MM_6330577E15RIK
ExpressionAtlas Q8BP27
Genevestigator Q8BP27
GO GO:0005634
GO:0032798
GO:0000724
InterPro IPR018468
Pfam PF10376

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000730

DNA recombinase assembly

PMID:22492707[1]

ECO:0000270

P

Fig. 2 shows the SWI5-SFR1 complex functions in stabilizing the Rad51 filament

complete
CACAO 4868

enables

GO:0030374

nuclear receptor transcription coactivator activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q86XK3

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q86XK3

P

Seeded From UniProt

complete

part_of

GO:0032798

Swi5-Sfr1 complex

PMID:20976249[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:20976249[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:20976249[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002008993
UniProtKB:Q86XK3

P

Seeded From UniProt

complete

part_of

GO:0032798

Swi5-Sfr1 complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1915038
PANTHER:PTN002008993
UniProtKB:Q86XK3

C

Seeded From UniProt

complete

enables

GO:0030374

nuclear receptor transcription coactivator activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002008993
UniProtKB:Q86XK3

F

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1915038
PANTHER:PTN002008993
UniProtKB:Q86XK3

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071391

cellular response to estrogen stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86XK3

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86XK3

P

Seeded From UniProt

complete

part_of

GO:0032798

Swi5-Sfr1 complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86XK3

C

Seeded From UniProt

complete

enables

GO:0030374

nuclear receptor transcription coactivator activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86XK3

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86XK3

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0000724

double-strand break repair via homologous recombination

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q86XK3

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Tsai, SP et al. (2012) Rad51 presynaptic filament stabilization function of the mouse Swi5-Sfr1 heterodimeric complex. Nucleic Acids Res. 40 6558-69 PubMed GONUTS page
  2. 2.0 2.1 2.2 Akamatsu, Y & Jasin, M (2010) Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet. 6 e1001160 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page