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MOUSE:RBP2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Ranbp2 | |
| Protein Name(s) | E3 SUMO-protein ligase RanBP2
Ran-binding protein 2 RanBP2 | |
| External Links | ||
| UniProt | Q9ERU9 | |
| EMBL | AF279458 AC158593 AK041932 X87337 | |
| CCDS | CCDS23861.1 | |
| PIR | S57968 | |
| RefSeq | NP_035370.2 | |
| UniGene | Mm.431695 | |
| ProteinModelPortal | Q9ERU9 | |
| SMR | Q9ERU9 | |
| BioGrid | 202582 | |
| IntAct | Q9ERU9 | |
| MINT | MINT-1659128 | |
| STRING | 10090.ENSMUSP00000003310 | |
| iPTMnet | Q9ERU9 | |
| PhosphoSite | Q9ERU9 | |
| EPD | Q9ERU9 | |
| MaxQB | Q9ERU9 | |
| PaxDb | Q9ERU9 | |
| PRIDE | Q9ERU9 | |
| Ensembl | ENSMUST00000003310 | |
| GeneID | 19386 | |
| KEGG | mmu:19386 | |
| UCSC | uc007fdd.1 | |
| CTD | 5903 | |
| MGI | MGI:894323 | |
| eggNOG | KOG0864 KOG0865 COG0652 COG5171 | |
| GeneTree | ENSGT00760000119119 | |
| HOGENOM | HOG000089994 | |
| HOVERGEN | HBG092361 | |
| InParanoid | Q9ERU9 | |
| KO | K12172 | |
| OMA | QWDCNVC | |
| OrthoDB | EOG7X0VG5 | |
| TreeFam | TF314797 | |
| Reactome | R-MMU-170822 R-MMU-2467813 R-MMU-2500257 R-MMU-3108214 R-MMU-3301854 R-MMU-4570464 R-MMU-4615885 R-MMU-5578749 R-MMU-5663220 R-MMU-68877 | |
| UniPathway | UPA00886 | |
| ChiTaRS | Ranbp2 | |
| NextBio | 296497 | |
| PRO | PR:Q9ERU9 | |
| Proteomes | UP000000589 | |
| Bgee | Q9ERU9 | |
| CleanEx | MM_RANBP2 | |
| Genevisible | Q9ERU9 | |
| GO | GO:1990723 GO:0005739 GO:0005635 GO:0042405 GO:0031965 GO:0044614 GO:0044615 GO:0016874 GO:0003755 GO:0003723 GO:0008270 GO:0046907 GO:0051028 GO:0033132 GO:0006457 GO:0016925 GO:0015031 GO:0090526 GO:0001975 | |
| Gene3D | 1.25.40.10 2.30.29.30 2.40.100.10 | |
| InterPro | IPR029000 IPR020892 IPR002130 IPR022011 IPR011993 IPR000156 IPR013026 IPR011990 IPR001440 IPR019734 IPR001876 | |
| Pfam | PF12185 PF00160 PF00638 PF00515 PF00641 | |
| PRINTS | PR00153 | |
| SMART | SM00160 SM00547 | |
| SUPFAM | SSF48452 SSF50729 SSF50891 SSF90209 | |
| PROSITE | PS00170 PS50072 PS50196 PS50005 PS50293 PS01358 PS50199 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005635 |
nuclear envelope |
ECO:0000314 |
C |
Figure 2B shows immunostaining of RanBP2 in the nuclear envelope. |
complete | |||||
|
part_of |
GO:0005643 |
nuclear pore |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005642 |
annulate lamellae |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005635 |
nuclear envelope |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044615 |
nuclear pore nuclear basket |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042405 |
nuclear inclusion body |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031965 |
nuclear membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016925 |
protein sumoylation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008536 |
Ran GTPase binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000566604 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006607 |
NLS-bearing protein import into nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002751291 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96269 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005643 |
nuclear pore |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1351502 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005643 |
nuclear pore |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1351502 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000566604 |
C |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0005096 |
GTPase activator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000566604 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019789 |
SUMO transferase activity |
ECO:0000269 |
experimental evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0033133 |
positive regulation of glucokinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0006111 |
regulation of gluconeogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3693886 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002609) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:1990723 |
cytoplasmic periphery of the nuclear pore complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R3M4 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R3M4 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0044614 |
nuclear pore cytoplasmic filaments |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R3M4 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005643 |
nuclear pore |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R3M4 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001975 |
response to amphetamine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R3M4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051642 |
centrosome localization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0044615 |
nuclear pore nuclear basket |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0044614 |
nuclear pore cytoplasmic filaments |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042405 |
nuclear inclusion body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031965 |
nuclear membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016925 |
protein sumoylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008536 |
Ran GTPase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006607 |
NLS-bearing protein import into nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005643 |
nuclear pore |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005642 |
annulate lamellae |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005635 |
nuclear envelope |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P49792 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000413 |
protein peptidyl-prolyl isomerization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003755 |
peptidyl-prolyl cis-trans isomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046907 |
intracellular transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005635 |
nuclear envelope |
Reactome:R-MMU-5228515 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005643 |
nuclear pore |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051028 |
mRNA transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005635 |
nuclear envelope |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031965 |
nuclear membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016925 |
protein sumoylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00886 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kazyken, D et al. (2014) The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget 5 9577-93 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Dawlaty, MM et al. (2008) Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell 133 103-15 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Aslanukov, A et al. (2006) RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet. 2 e177 PubMed GONUTS page
c
m
n
p
- GO:0003755 ! peptidyl-prolyl cis-trans isomerase activity
- GO:0043547 ! positive regulation of GTPase activity
- GO:0033133 ! positive regulation of glucokinase activity
- GO:0044877 ! protein-containing complex binding
- GO:0006457 ! protein folding
- GO:0000413 ! protein peptidyl-prolyl isomerization
- GO:0016925 ! protein sumoylation
- GO:0015031 ! protein transport
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