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MOUSE:RBBP5

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Rbbp5
Protein Name(s) Retinoblastoma-binding protein 5

RBBP-5

External Links
UniProt Q8BX09
EMBL AK049247
AK154782
AK171177
CH466520
BC057632
BC060186
CCDS CCDS15286.1
RefSeq NP_766105.2
UniGene Mm.132868
PDB 2XL2
2XL3
PDBsum 2XL2
2XL3
ProteinModelPortal Q8BX09
SMR Q8BX09
BioGrid 229436
DIP DIP-61809N
IntAct Q8BX09
MINT Q8BX09
STRING 10090.ENSMUSP00000027700
iPTMnet Q8BX09
PhosphoSitePlus Q8BX09
EPD Q8BX09
PaxDb Q8BX09
PeptideAtlas Q8BX09
PRIDE Q8BX09
Ensembl ENSMUST00000027700
ENSMUST00000190997
GeneID 213464
KEGG mmu:213464
UCSC uc007cow.2
uc007coy.2
CTD 5929
MGI MGI:1918367
eggNOG KOG1273
ENOG410XTA2
GeneTree ENSGT00530000064100
HOGENOM HOG000204856
HOVERGEN HBG054324
InParanoid Q8BX09
KO K14961
OMA FRMPILF
OrthoDB EOG091G038T
PhylomeDB Q8BX09
TreeFam TF313289
Reactome R-MMU-201722
R-MMU-3214841
R-MMU-3769402
R-MMU-8936459
R-MMU-8951664
EvolutionaryTrace Q8BX09
PRO PR:Q8BX09
Proteomes UP000000589
Bgee ENSMUSG00000026439
ExpressionAtlas Q8BX09
Genevisible Q8BX09
GO GO:0035097
GO:0071339
GO:0044666
GO:0005730
GO:0005654
GO:0005634
GO:0048188
GO:0042800
GO:0035064
GO:0044212
GO:0006974
GO:0051568
GO:0006355
GO:0043627
GO:0006351
Gene3D 2.130.10.10
InterPro IPR037850
IPR015943
IPR001680
IPR017986
PANTHER PTHR44040
Pfam PF00400
SMART SM00320
PROSITE PS50082
PS50294

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0071339

MLL1 complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0071339

MLL1 complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051568

histone H3-K4 methylation

PMID:24051374[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • has_input:(MGI:MGI:95607)
  • occurs_in:(EMAPA:16846)|occurs_in:(EMAPA:16846)
  • has_input:(MGI:MGI:95701)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051568

histone H3-K4 methylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

P

Seeded From UniProt

complete

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0044666

MLL3/4 complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043627

response to estrogen

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

P

Seeded From UniProt

complete

contributes_to

GO:0042800

histone methyltransferase activity (H3-K4 specific)

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

F

Seeded From UniProt

complete

part_of

GO:0035097

histone methyltransferase complex

PMID:17500065[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0035097

histone methyltransferase complex

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

enables

GO:0035064

methylated histone binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006974

cellular response to DNA damage stimulus

PMID:17500065[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:17500065[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15291

C

Seeded From UniProt

complete

part_of

GO:0071339

MLL1 complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

involved_in

GO:0051568

histone H3-K4 methylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

P

Seeded From UniProt

complete

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

part_of

GO:0044666

MLL3/4 complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

F

Seeded From UniProt

complete

involved_in

GO:0043627

response to estrogen

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

P

Seeded From UniProt

complete

enables

GO:0042800

histone methyltransferase activity (H3-K4 specific)

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

F

Seeded From UniProt

complete

part_of

GO:0035097

histone methyltransferase complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

enables

GO:0035064

methylated histone binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15291
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A0A024R9B5
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A0A024R9B5
ensembl:ENSP00000264515

C

Seeded From UniProt

complete

part_of

GO:0048188

Set1C/COMPASS complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037850

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-MMU-6810170
Reactome:R-MMU-6810169
Reactome:R-MMU-6810150
Reactome:R-MMU-5693628
Reactome:R-MMU-5621012
Reactome:R-MMU-5621004
Reactome:R-MMU-5619441
Reactome:R-MMU-5619440
Reactome:R-MMU-5619437
Reactome:R-MMU-5619436
Reactome:R-MMU-5619434
Reactome:R-MMU-5619430
Reactome:R-MMU-5619424
Reactome:R-MMU-5619411
Reactome:R-MMU-5617990
Reactome:R-MMU-5617960

ECO:0000304

author statement supported by traceable reference used in manual assertion
















C

Seeded From UniProt

complete

involved_in

GO:0006325

chromatin organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0156

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Ravnskjaer, K et al. (2013) Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J. Clin. Invest. 123 4318-28 PubMed GONUTS page
  2. 2.0 2.1 2.2 Cho, YW et al. (2007) PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. J. Biol. Chem. 282 20395-406 PubMed GONUTS page