MOUSE:RAD52

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Rad52
Protein Name(s)	DNA repair protein RAD52 homolog
External Links
UniProt	P43352
EMBL	U06837 U12135 Z32767 AF004854
CCDS	CCDS51887.1
PIR	A55727 A56529
RefSeq	NP_001159853.1
UniGene	Mm.149
ProteinModelPortal	P43352
SMR	P43352
STRING	10090.ENSMUSP00000032269
PhosphoSite	P43352
PaxDb	P43352
PRIDE	P43352
Ensembl	ENSMUST00000162461
GeneID	19365
KEGG	mmu:19365
UCSC	uc009dmq.2
CTD	5893
MGI	MGI:101949
eggNOG	COG5055
GeneTree	ENSGT00390000008766
HOVERGEN	HBG054676
InParanoid	P43352
KO	K10873
OMA	QARYSSC
OrthoDB	EOG74XS87
PhylomeDB	P43352
TreeFam	TF101221
Reactome	REACT_235085 REACT_261855
NextBio	296437
PRO	PR:P43352
Proteomes	UP000000589
Bgee	P43352
CleanEx	MM_RAD52
ExpressionAtlas	P43352
Genevestigator	P43352
GO	GO:0005634 GO:0003677 GO:0006310 GO:0000724
InterPro	IPR004585 IPR007232
PANTHER	PTHR12132
Pfam	PF04098
TIGRFAMs	TIGR00607

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	PMID:22912580^[1]	ECO:0000315			P	Refer to Fig. 6	complete CACAO 5414
involved_in	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	PMID:22912580^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
involved_in	GO:0045002	double-strand break repair via single-strand annealing	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000951175 SGD:S000002217 SGD:S000004494 UniProtKB:A0A1D8PM97	P	Seeded From UniProt	complete
involved_in	GO:0006312	mitotic recombination	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000951175 PomBase:SPAC30D11.10 UniProtKB:Q59NG2	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000951175 PomBase:SPAC30D11.10 SGD:S000002217 SGD:S000004494 UniProtKB:P43351	C	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101949 PANTHER:PTN000951175 PomBase:SPAC30D11.10 SGD:S000004494	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000819	regulation of nucleotide-excision repair	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051260	protein homooligomerization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034599	cellular response to oxidative stress	PMID:19506022^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034599	cellular response to oxidative stress	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
part_of	GO:0032993	protein-DNA complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	C	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006974	cellular response to DNA damage stimulus	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006310	DNA recombination	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	C	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:19506022^[3]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P43351	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000724	double-strand break repair via homologous recombination	PMID:12379650^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:2000819	regulation of nucleotide-excision repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	P	Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	P	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	F	Seeded From UniProt	complete
involved_in	GO:0034599	cellular response to oxidative stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	P	Seeded From UniProt	complete
part_of	GO:0032993	protein-DNA complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	C	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	C	Seeded From UniProt	complete
involved_in	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	P	Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	C	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43351 ensembl:ENSP00000351284	F	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004585	P	Seeded From UniProt	complete
involved_in	GO:0000730	DNA recombinase assembly	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004585	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004585	C	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007232	P	Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007232	P	Seeded From UniProt	complete
involved_in	GO:0045002	double-strand break repair via single-strand annealing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004585	P	Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0233	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Schumacher, AJ et al. (2012) The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism. PLoS Pathog. 8 e1002862 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 de Souza-Pinto, NC et al. (2009) The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. Mol. Cell. Biol. 29 4441-54 PubMed GONUTS page
↑ Kitao, H & Yuan, ZM (2002) Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation. J. Biol. Chem. 277 48944-8 PubMed GONUTS page

[PMID:22912580-1] 1.0 ^1.1 Schumacher, AJ et al. (2012) The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism. PLoS Pathog. 8 e1002862 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19506022-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 de Souza-Pinto, NC et al. (2009) The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. Mol. Cell. Biol. 29 4441-54 PubMed GONUTS page

[PMID:12379650-4] Kitao, H & Yuan, ZM (2002) Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation. J. Biol. Chem. 277 48944-8 PubMed GONUTS page

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MOUSE:RAD52

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