MOUSE:Q3TZI5

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Msh2 (ECO:0000313 with EMBL:EDL38635.1, ECO:0000313 with MGI:MGI:101816)
Protein Name(s)	MutS homolog 2 (E. coli) (ECO:0000313 with EMBL:EDL38635.1)
External Links
UniProt	Q3TZI5
EMBL	AK157842 CH466537
RefSeq	NP_032654.1
UniGene	Mm.4619
SMR	Q3TZI5
GeneID	17685
KEGG	mmu:17685
CTD	4436
MGI	MGI:101816
GeneTree	ENSGT00550000074867
HOVERGEN	HBG006399
KO	K08735
OMA	TLQDCYR
PhylomeDB	Q3TZI5
NextBio	292252
Genevestigator	Q3TZI5
GO	GO:0016020 GO:0032301 GO:0032302 GO:0000228 GO:0005634 GO:0043531 GO:0005524 GO:0016887 GO:0019237 GO:0003684 GO:0032181 GO:0003677 GO:0008094 GO:0000406 GO:0000400 GO:0032137 GO:0000404 GO:0000287 GO:0030983 GO:0032357 GO:0032138 GO:0032142 GO:0032143 GO:0003697 GO:0000403 GO:0006200 GO:0030183 GO:0019724 GO:0007050 GO:0006974 GO:0008340 GO:0006281 GO:0006302 GO:0007281 GO:0001701 GO:0031573 GO:0008630 GO:0042771 GO:0045190 GO:0043570 GO:0008584 GO:0006311 GO:0000710 GO:0006298 GO:0045910 GO:0043524 GO:0045128 GO:0006119 GO:0051096 GO:0006301 GO:0010224 GO:0010165 GO:0016446 GO:0016447 GO:0002204
Gene3D	3.30.420.110 3.40.50.300
InterPro	IPR011184 IPR007695 IPR000432 IPR007861 IPR007696 IPR007860 IPR027417
Pfam	PF01624 PF05188 PF05192 PF05190 PF00488
PIRSF	PIRSF005813
SMART	SM00534 SM00533
SUPFAM	SSF48334 SSF52540 SSF53150
PROSITE	PS00486

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0071168	protein localization to chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
involved_in	GO:0051096	positive regulation of helicase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
involved_in	GO:0045910	negative regulation of DNA recombination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
involved_in	GO:0043570	maintenance of DNA repeat elements	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
enables	GO:0043531	ADP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0032405	MutLalpha complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0032357	oxidized purine DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
part_of	GO:0032302	MutSbeta complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	C	Seeded From UniProt	complete
part_of	GO:0032301	MutSalpha complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	C	Seeded From UniProt	complete
enables	GO:0032181	dinucleotide repeat insertion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0032143	single thymine insertion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0032142	single guanine insertion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0032139	dinucleotide insertion or deletion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0032137	guanine/thymine mispair binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0030983	mismatched DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
involved_in	GO:0006301	postreplication repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0000400	four-way junction DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P43246 ensembl:ENSP00000233146	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032642	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432 InterPro:IPR007695 InterPro:IPR007696 InterPro:IPR007860 InterPro:IPR007861 InterPro:IPR011184 InterPro:IPR016151 InterPro:IPR032642 InterPro:IPR036678	F	Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432 InterPro:IPR007695 InterPro:IPR007696 InterPro:IPR007860 InterPro:IPR007861 InterPro:IPR011184 InterPro:IPR016151 InterPro:IPR032642 InterPro:IPR036678	P	Seeded From UniProt	complete
enables	GO:0030983	mismatched DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432 InterPro:IPR007695 InterPro:IPR007696 InterPro:IPR007860 InterPro:IPR007861 InterPro:IPR011184 InterPro:IPR016151 InterPro:IPR036678	F	Seeded From UniProt	complete
part_of	GO:0032300	mismatch repair complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032642	C	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
part_of	GO:0032301	MutSalpha complex	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000146905	C	Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000146905	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000146905	C	Seeded From UniProt	complete
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MOUSE:Q3TZI5

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