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MOUSE:PLS3

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Plscr3
Protein Name(s) Phospholipid scramblase 3

PL scramblase 3 Ca(2+)-dependent phospholipid scramblase 3

External Links
UniProt Q9JIZ9
EMBL AF159850
AK011716
AK029154
AK075841
BC020143
CCDS CCDS24916.1
RefSeq NP_001161969.1
NP_076053.1
XP_006534219.1
XP_006534220.1
UniGene Mm.28874
ProteinModelPortal Q9JIZ9
PhosphoSite Q9JIZ9
MaxQB Q9JIZ9
PaxDb Q9JIZ9
PRIDE Q9JIZ9
Ensembl ENSMUST00000019605
ENSMUST00000108632
ENSMUST00000108633
GeneID 70310
KEGG mmu:70310
UCSC uc007jrz.2
CTD 57048
MGI MGI:1917560
eggNOG NOG119855
GeneTree ENSGT00390000002884
HOGENOM HOG000237356
HOVERGEN HBG019157
InParanoid Q9JIZ9
OMA LLGWETC
OrthoDB EOG77T14X
PhylomeDB Q9JIZ9
TreeFam TF314939
NextBio 331360
PRO PR:Q9JIZ9
Proteomes UP000000589
Bgee Q9JIZ9
CleanEx MM_PLSCR3
ExpressionAtlas Q9JIZ9
Genevestigator Q9JIZ9
GO GO:0016021
GO:0031966
GO:0006915
GO:0071222
GO:0042632
GO:0042593
InterPro IPR005552
PANTHER PTHR23248
Pfam PF03803

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071222

cellular response to lipopolysaccharide

PMID:17590392[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0017128

phospholipid scramblase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000582979
UniProtKB:O15162
WB:WBGene00011935

F

Seeded From UniProt

complete

involved_in

GO:0017121

plasma membrane phospholipid scrambling

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:893575
PANTHER:PTN000582979
RGD:620521
UniProtKB:O15162
WB:WBGene00011935

P

Seeded From UniProt

complete

enables

GO:0048306

calcium-dependent protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NRY6

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042632

cholesterol homeostasis

PMID:15328404[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3053448

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042593

glucose homeostasis

PMID:15328404[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3053448

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NRY6

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NRY6

C

Seeded From UniProt

complete

colocalizes_with

GO:0005739

mitochondrion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1307016

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6QBQ4
ensembl:ENSRNOP00000035566

C

Seeded From UniProt

complete

enables

GO:0048306

calcium-dependent protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRY6
ensembl:ENSP00000459019

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRY6
ensembl:ENSP00000459019

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NRY6
ensembl:ENSP00000459019

C

Seeded From UniProt

complete

enables

GO:0017124

SH3 domain binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0729

F

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0031966

mitochondrial membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0171

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Lu, B et al. (2007) Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response. Biochim. Biophys. Acta 1771 1177-85 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Wiedmer, T et al. (2004) Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Proc. Natl. Acad. Sci. U.S.A. 101 13296-301 PubMed GONUTS page