GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:PLIN2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Plin2 (synonyms: Adfp, Adrp)
Protein Name(s) Perilipin-2

Adipophilin Adipose differentiation-related protein ADRP

External Links
UniProt P43883
EMBL M93275
L09734
AY035850
AK150177
AK152081
AK152263
AK153222
AK154582
AK167140
AL824707
BC054766
CCDS CCDS18308.1
PIR A46251
RefSeq NP_031434.3
XP_006537620.1
UniGene Mm.381
ProteinModelPortal P43883
SMR P43883
BioGrid 197983
PhosphoSite P43883
MaxQB P43883
PaxDb P43883
PRIDE P43883
DNASU 11520
Ensembl ENSMUST00000000466
GeneID 11520
KEGG mmu:11520
UCSC uc008tlz.1
CTD 123
MGI MGI:87920
eggNOG NOG68493
GeneTree ENSGT00500000044795
HOGENOM HOG000033816
HOVERGEN HBG002935
InParanoid P43883
KO K17284
OMA TKDNHPY
OrthoDB EOG7SN8CD
TreeFam TF328397
Reactome REACT_198602
NextBio 278956
PRO PR:P43883
Proteomes UP000000589
Bgee P43883
CleanEx MM_ADFP
ExpressionAtlas P43883
Genevestigator P43883
GO GO:0005737
GO:0005829
GO:0005811
GO:0005634
GO:0005886
GO:0019915
GO:0015909
GO:0042493
GO:0014070
InterPro IPR004279
PANTHER PTHR14024
Pfam PF03036
PIRSF PIRSF036881

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010885

regulation of cholesterol storage

PMID:F22427949

ECO:0000314

P

Figure 3 shows that "Perilipin 2 deficiency does not increase cholesterol-induced toxicity in macrophages".

complete
CACAO 6148

acts_upstream_of_or_within

GO:0019915

lipid storage

PMID:12562852[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0015909

long-chain fatty acid transport

PMID:10358026[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:10358026[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:16571721[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:16105)

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

PMID:16571721[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:16105)|part_of:(CL:0000178)

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

PMID:12562852[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q99541

C

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:728889

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:16581799[4]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:16042)
  • part_of:(CL:0000351)

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:10358026[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0042493

response to drug

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F6QBA3
ensembl:ENSRNOP00000009749

P

Seeded From UniProt

complete

involved_in

GO:0014070

response to organic cyclic compound

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F6QBA3
ensembl:ENSRNOP00000009749

P

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F6QBA3
ensembl:ENSRNOP00000009749

C

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6FHZ7
ensembl:ENSP00000276914

C

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99541
ensembl:ENSP00000276914

C

Seeded From UniProt

complete

part_of

GO:0005811

lipid droplet

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0551
UniProtKB-SubCell:SL-0154

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 McManaman, JL et al. (2003) Lipid droplet targeting domains of adipophilin. J. Lipid Res. 44 668-73 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gao, J & Serrero, G (1999) Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake. J. Biol. Chem. 274 16825-30 PubMed GONUTS page
  3. 3.0 3.1 Yamaguchi, T et al. (2006) MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 281 14232-40 PubMed GONUTS page
  4. Nadra, K et al. (2006) Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol. Cell. Biol. 26 3266-81 PubMed GONUTS page