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MOUSE:PLIN2
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Plin2 (synonyms: Adfp, Adrp) | |
Protein Name(s) | Perilipin-2
Adipophilin Adipose differentiation-related protein ADRP | |
External Links | ||
UniProt | P43883 | |
EMBL | M93275 L09734 AY035850 AK150177 AK152081 AK152263 AK153222 AK154582 AK167140 AL824707 BC054766 | |
CCDS | CCDS18308.1 | |
PIR | A46251 | |
RefSeq | NP_031434.3 XP_006537620.1 | |
UniGene | Mm.381 | |
ProteinModelPortal | P43883 | |
SMR | P43883 | |
BioGrid | 197983 | |
PhosphoSite | P43883 | |
MaxQB | P43883 | |
PaxDb | P43883 | |
PRIDE | P43883 | |
DNASU | 11520 | |
Ensembl | ENSMUST00000000466 | |
GeneID | 11520 | |
KEGG | mmu:11520 | |
UCSC | uc008tlz.1 | |
CTD | 123 | |
MGI | MGI:87920 | |
eggNOG | NOG68493 | |
GeneTree | ENSGT00500000044795 | |
HOGENOM | HOG000033816 | |
HOVERGEN | HBG002935 | |
InParanoid | P43883 | |
KO | K17284 | |
OMA | TKDNHPY | |
OrthoDB | EOG7SN8CD | |
TreeFam | TF328397 | |
Reactome | REACT_198602 | |
NextBio | 278956 | |
PRO | PR:P43883 | |
Proteomes | UP000000589 | |
Bgee | P43883 | |
CleanEx | MM_ADFP | |
ExpressionAtlas | P43883 | |
Genevestigator | P43883 | |
GO | GO:0005737 GO:0005829 GO:0005811 GO:0005634 GO:0005886 GO:0019915 GO:0015909 GO:0042493 GO:0014070 | |
InterPro | IPR004279 | |
PANTHER | PTHR14024 | |
Pfam | PF03036 | |
PIRSF | PIRSF036881 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0010885 |
regulation of cholesterol storage |
PMID:F22427949 |
ECO:0000314 |
P |
Figure 3 shows that "Perilipin 2 deficiency does not increase cholesterol-induced toxicity in macrophages". |
complete | ||||
acts_upstream_of_or_within |
GO:0019915 |
lipid storage |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0015909 |
long-chain fatty acid transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16105) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16105)|part_of:(CL:0000178) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:728889 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042493 |
response to drug |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:F6QBA3 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0014070 |
response to organic cyclic compound |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:F6QBA3 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:F6QBA3 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q6FHZ7 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99541 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005811 |
lipid droplet |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 McManaman, JL et al. (2003) Lipid droplet targeting domains of adipophilin. J. Lipid Res. 44 668-73 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gao, J & Serrero, G (1999) Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake. J. Biol. Chem. 274 16825-30 PubMed GONUTS page
- ↑ 3.0 3.1 Yamaguchi, T et al. (2006) MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 281 14232-40 PubMed GONUTS page
- ↑ Nadra, K et al. (2006) Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol. Cell. Biol. 26 3266-81 PubMed GONUTS page