MOUSE:NCOR1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Ncor1 (synonyms: Rxrip13)
Protein Name(s)	Nuclear receptor corepressor 1 N-CoR N-CoR1 Retinoid X receptor-interacting protein 13 RIP13
External Links
UniProt	Q60974
EMBL	U35312 U22016
PIR	S60254
UniGene	Mm.271814 Mm.460227
ProteinModelPortal	Q60974
SMR	Q60974
DIP	DIP-32548N
IntAct	Q60974
MINT	MINT-2981744
PhosphoSite	Q60974
MaxQB	Q60974
PaxDb	Q60974
PRIDE	Q60974
MGI	MGI:1349717
eggNOG	NOG12793
HOVERGEN	HBG052587
InParanoid	Q60974
Reactome	REACT_252217 REACT_27166
ChiTaRS	Ncor1
PRO	PR:Q60974
Proteomes	UP000000589
CleanEx	MM_NCOR1
Genevestigator	Q60974
GO	GO:0005737 GO:0005829 GO:0005654 GO:0005634 GO:0005667 GO:0017053 GO:0003682 GO:0003677 GO:0035033 GO:0019904 GO:0042974 GO:0046965 GO:0043565 GO:0003700 GO:0046966 GO:0003714 GO:0044212 GO:0002361 GO:0042632 GO:0016568 GO:0032922 GO:0060318 GO:0014067 GO:0000122 GO:0045892 GO:0031065 GO:0040014 GO:0006357 GO:0021794 GO:0006351
Gene3D	1.10.10.60
InterPro	IPR009057 IPR001005 IPR017884
Pfam	PF00249
SMART	SM00717
SUPFAM	SSF46689
PROSITE	PS51293

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:24794873^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045475	locomotor rhythm	PMID:19037247^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	PMID:16127449^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	PMID:15175761^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q923E4	F		Seeded From UniProt	complete
enables	GO:0046966	thyroid hormone receptor binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1349717 PANTHER:PTN002678500	F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1337080 MGI:MGI:1349717 PANTHER:PTN001400465	F		Seeded From UniProt	complete
enables	GO:0042826	histone deacetylase binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001400465 UniProtKB:O75376 UniProtKB:Q9Y618	F		Seeded From UniProt	complete
enables	GO:0035257	nuclear hormone receptor binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1349717 PANTHER:PTN002303952 RGD:1310293 RGD:3612 UniProtKB:O75376	F		Seeded From UniProt	complete
part_of	GO:0017053	transcriptional repressor complex	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0265523 MGI:MGI:1349717 PANTHER:PTN001400465 UniProtKB:O75376 UniProtKB:Q9Y618	C		Seeded From UniProt	complete
colocalizes_with	GO:0016580	Sin3 complex	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002678500 UniProtKB:O75376	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1337080 MGI:MGI:1349717 PANTHER:PTN001400465 PomBase:SPAC22E12.19 RGD:1310293 RGD:3612 SGD:S000000629 UniProtKB:Q9Y618	C		Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1337080 MGI:MGI:1349717 PANTHER:PTN001400465 UniProtKB:O75376 UniProtKB:Q9Y618	F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0265523 MGI:MGI:1337080 PANTHER:PTN001400465 RGD:1310293 RGD:3612	F		Seeded From UniProt	complete
enables	GO:0001012	RNA polymerase II regulatory region DNA binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001400465 RGD:1310293 RGD:3612	F		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001400465 PomBase:SPAC22E12.19 SGD:S000000629 UniProtKB:Q9Y618	C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1337080 MGI:MGI:1349717 PANTHER:PTN001400465 UniProtKB:O75376 UniProtKB:Q9Y618	P		Seeded From UniProt	complete
part_of	GO:0000118	histone deacetylase complex	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1337080 PANTHER:PTN001400465 PomBase:SPAC22E12.19 SGD:S000000629	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904017	cellular response to Thyroglobulin triiodothyronine	PMID:24550004^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1276523	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
part_of	GO:0072686	mitotic spindle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0072362	regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060766	negative regulation of androgen receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060318	definitive erythrocyte differentiation	PMID:11030619^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677822	P	occurs_in:(EMAPA:16846) results_in_acquisition_of_features_of:(CL:0000232)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051225	spindle assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	C		Seeded From UniProt	complete
enables	GO:0046966	thyroid hormone receptor binding	PMID:19052228^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P37242 UniProtKB:Q9Z0Y9	F		Seeded From UniProt	complete
enables	GO:0046966	thyroid hormone receptor binding	PMID:8961273^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0046965	retinoid X receptor binding	PMID:8961273^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0046965	retinoid X receptor binding	PMID:7760852^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0046965	retinoid X receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046329	negative regulation of JNK cascade	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045892	negative regulation of transcription, DNA-templated	PMID:15681609^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045892	negative regulation of transcription, DNA-templated	PMID:15695367^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:17928865^[13]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_in:(EMAPA:16910) has_input:(MGI:MGI:95697)\|occurs_in(EMAPA:16910) has_input:(MGI:MGI:1277171)	Seeded From UniProt	complete
enables	GO:0042975	peroxisome proliferator activated receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
enables	GO:0042974	retinoic acid receptor binding	PMID:8961273^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0042974	retinoic acid receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
enables	GO:0042826	histone deacetylase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042632	cholesterol homeostasis	PMID:19052228^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3821874	P	has_participant:(EMAPA:35770)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0040014	regulation of multicellular organism growth	PMID:19037247^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1343091	P		Seeded From UniProt	complete
enables	GO:0035257	nuclear hormone receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	F		Seeded From UniProt	complete
enables	GO:0035033	histone deacetylase regulator activity	PMID:15695367^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0035033	histone deacetylase regulator activity	PMID:19037247^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032922	circadian regulation of gene expression	PMID:19037247^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1343091	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031065	positive regulation of histone deacetylation	PMID:19037247^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0030331	estrogen receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021794	thalamus development	PMID:11030619^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677822	P	results_in_development_of:(EMAPA:17540)	Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
part_of	GO:0017053	transcriptional repressor complex	PMID:17182846^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O09106 UniProtKB:P05627 UniProtKB:P70288 UniProtKB:Q60520 UniProtKB:Q9QYB2	C		Seeded From UniProt	complete
part_of	GO:0017053	transcriptional repressor complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
colocalizes_with	GO:0016580	Sin3 complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	PMID:17606624^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010629	negative regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006357	regulation of transcription by RNA polymerase II	PMID:19052228^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:98743	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:17606624^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	C		Seeded From UniProt	complete
part_of	GO:0005667	transcription factor complex	PMID:17182846^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O09106 UniProtKB:P05627 UniProtKB:P70288 UniProtKB:Q60520 UniProtKB:Q9QYB2	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19052228^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17606624^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16030140^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:11092755^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	PMID:7566114^[18]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:97856 MGI:MGI:98743	F		Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	PMID:11030619^[7]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1352467	F		Seeded From UniProt	complete
enables	GO:0003714	transcription corepressor activity	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:17392792^[19]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:15681609^[11]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:14980219^[20]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	PMID:11030619^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677822	P	results_in_acquisition_of_features_of:(CL:0000809)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002155	regulation of thyroid hormone mediated signaling pathway	PMID:24550004^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1276523	P		Seeded From UniProt	complete
enables	GO:0001102	RNA polymerase II activating transcription factor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	F		Seeded From UniProt	complete
enables	GO:0001012	RNA polymerase II regulatory region DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3612	F		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:7566114^[18]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:97856 MGI:MGI:98743	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:16421255^[21]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107365	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:16030140^[16]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P10037	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:11030619^[7]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1352467	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:19299558^[22]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677822	P	occurs_in:(CL:0000235)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:11328825^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(EMAPA:16846)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	P		Seeded From UniProt	complete
part_of	GO:0000118	histone deacetylase complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O75376	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009057	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-NUL-1253330 Reactome:R-NUL-1253318	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-NUL-9005752 Reactome:R-NUL-9005747 Reactome:R-NUL-1253330 Reactome:R-MMU-5667077 Reactome:R-MMU-5619441 Reactome:R-MMU-5619434 Reactome:R-MMU-5619411 Reactome:R-MMU-5617990 Reactome:R-MMU-5617960 Reactome:R-MMU-556760 Reactome:R-MMU-442515	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0156	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Aninye, IO et al. (2014) Circadian regulation of Tshb gene expression by Rev-Erbα (NR1D1) and nuclear corepressor 1 (NCOR1). J. Biol. Chem. 289 17070-7 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Alenghat, T et al. (2008) Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature 456 997-1000 PubMed GONUTS page
↑ Pascual, G et al. (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437 759-63 PubMed GONUTS page
↑ Picard, F et al. (2004) Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 429 771-6 PubMed GONUTS page
↑ ^5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 ^5.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^6.0 ^6.1 Vella, KR et al. (2014) Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. Mol. Cell. Biol. 34 1564-75 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 Jepsen, K et al. (2000) Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102 753-63 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 Astapova, I et al. (2008) The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo. Proc. Natl. Acad. Sci. U.S.A. 105 19544-9 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Seol, W et al. (1996) Two receptor interacting domains in the nuclear hormone receptor corepressor RIP13/N-CoR. Mol. Endocrinol. 10 1646-55 PubMed GONUTS page
↑ Seol, W et al. (1995) Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Mol. Endocrinol. 9 72-85 PubMed GONUTS page
↑ ^11.0 ^11.1 Guan, HP et al. (2005) Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev. 19 453-61 PubMed GONUTS page
↑ ^12.0 ^12.1 Ishizuka, T & Lazar, MA (2005) The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor. Mol. Endocrinol. 19 1443-51 PubMed GONUTS page
↑ Jepsen, K et al. (2007) SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature 450 415-9 PubMed GONUTS page
↑ ^14.0 ^14.1 Wu, K et al. (2007) Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol. Biol. Cell 18 755-67 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 Furuya, F et al. (2007) Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling. Mol. Cell. Biol. 27 6116-26 PubMed GONUTS page
↑ ^16.0 ^16.1 Voss, TC et al. (2005) Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus. J. Cell. Sci. 118 3277-88 PubMed GONUTS page
↑ Hilditch-Maguire, P et al. (2000) Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles. Hum. Mol. Genet. 9 2789-97 PubMed GONUTS page
↑ ^18.0 ^18.1 Hörlein, AJ et al. (1995) Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377 397-404 PubMed GONUTS page
↑ Wang, J et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446 882-7 PubMed GONUTS page
↑ Perissi, V et al. (2004) A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell 116 511-26 PubMed GONUTS page
↑ Tiefenbach, J et al. (2006) SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription. Mol. Biol. Cell 17 1643-51 PubMed GONUTS page
↑ Ghisletti, S et al. (2009) Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 23 681-93 PubMed GONUTS page
↑ Feng, X et al. (2001) Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation. J. Biol. Chem. 276 15066-72 PubMed GONUTS page

[PMID:24794873-1] Aninye, IO et al. (2014) Circadian regulation of Tshb gene expression by Rev-Erbα (NR1D1) and nuclear corepressor 1 (NCOR1). J. Biol. Chem. 289 17070-7 PubMed GONUTS page

[PMID:19037247-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Alenghat, T et al. (2008) Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature 456 997-1000 PubMed GONUTS page

[PMID:16127449-3] Pascual, G et al. (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437 759-63 PubMed GONUTS page

[PMID:15175761-4] Picard, F et al. (2004) Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 429 771-6 PubMed GONUTS page

[PMID:21873635-5] 5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 ^5.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:24550004-6] 6.0 ^6.1 Vella, KR et al. (2014) Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. Mol. Cell. Biol. 34 1564-75 PubMed GONUTS page

[PMID:11030619-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 Jepsen, K et al. (2000) Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102 753-63 PubMed GONUTS page

[PMID:19052228-8] 8.0 ^8.1 ^8.2 ^8.3 Astapova, I et al. (2008) The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo. Proc. Natl. Acad. Sci. U.S.A. 105 19544-9 PubMed GONUTS page

[PMID:8961273-9] 9.0 ^9.1 ^9.2 Seol, W et al. (1996) Two receptor interacting domains in the nuclear hormone receptor corepressor RIP13/N-CoR. Mol. Endocrinol. 10 1646-55 PubMed GONUTS page

[PMID:7760852-10] Seol, W et al. (1995) Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Mol. Endocrinol. 9 72-85 PubMed GONUTS page

[PMID:15681609-11] 11.0 ^11.1 Guan, HP et al. (2005) Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev. 19 453-61 PubMed GONUTS page

[PMID:15695367-12] 12.0 ^12.1 Ishizuka, T & Lazar, MA (2005) The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor. Mol. Endocrinol. 19 1443-51 PubMed GONUTS page

[PMID:17928865-13] Jepsen, K et al. (2007) SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature 450 415-9 PubMed GONUTS page

[PMID:17182846-14] 14.0 ^14.1 Wu, K et al. (2007) Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol. Biol. Cell 18 755-67 PubMed GONUTS page

[PMID:17606624-15] 15.0 ^15.1 ^15.2 Furuya, F et al. (2007) Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling. Mol. Cell. Biol. 27 6116-26 PubMed GONUTS page

[PMID:16030140-16] 16.0 ^16.1 Voss, TC et al. (2005) Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus. J. Cell. Sci. 118 3277-88 PubMed GONUTS page

[PMID:11092755-17] Hilditch-Maguire, P et al. (2000) Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles. Hum. Mol. Genet. 9 2789-97 PubMed GONUTS page

[PMID:7566114-18] 18.0 ^18.1 Hörlein, AJ et al. (1995) Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377 397-404 PubMed GONUTS page

[PMID:17392792-19] Wang, J et al. (2007) Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature 446 882-7 PubMed GONUTS page

[PMID:14980219-20] Perissi, V et al. (2004) A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. Cell 116 511-26 PubMed GONUTS page

[PMID:16421255-21] Tiefenbach, J et al. (2006) SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription. Mol. Biol. Cell 17 1643-51 PubMed GONUTS page

[PMID:19299558-22] Ghisletti, S et al. (2009) Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 23 681-93 PubMed GONUTS page

[PMID:11328825-23] Feng, X et al. (2001) Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation. J. Biol. Chem. 276 15066-72 PubMed GONUTS page

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MOUSE:NCOR1

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