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MOUSE:MDR1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Abcb1b (synonyms: Abcb1, Mdr1, Mdr1b, Pgy1, Pgy1-1) | |
| Protein Name(s) | Multidrug resistance protein 1B
ATP-binding cassette sub-family B member 1B P-glycoprotein 1 | |
| External Links | ||
| UniProt | P06795 | |
| EMBL | M14757 M60348 | |
| CCDS | CCDS19085.1 | |
| PIR | A33719 | |
| RefSeq | NP_035205.1 | |
| UniGene | Mm.146649 Mm.389059 | |
| ProteinModelPortal | P06795 | |
| IntAct | P06795 | |
| MINT | MINT-4101676 | |
| STRING | 10090.ENSMUSP00000009058 | |
| BindingDB | P06795 | |
| ChEMBL | CHEMBL2111404 | |
| PhosphoSite | P06795 | |
| MaxQB | P06795 | |
| PaxDb | P06795 | |
| PRIDE | P06795 | |
| Ensembl | ENSMUST00000009058 | |
| GeneID | 18669 | |
| KEGG | mmu:18669 | |
| UCSC | uc008wko.2 | |
| CTD | 18669 | |
| MGI | MGI:97568 | |
| eggNOG | COG1132 | |
| GeneTree | ENSGT00530000062896 | |
| HOVERGEN | HBG080809 | |
| InParanoid | P06795 | |
| KO | K05658 | |
| OMA | CAVINGC | |
| OrthoDB | EOG7Z3F4H | |
| PhylomeDB | P06795 | |
| TreeFam | TF105193 | |
| Reactome | REACT_237882 | |
| SABIO-RK | P06795 | |
| NextBio | 294678 | |
| PRO | PR:P06795 | |
| Proteomes | UP000000589 | |
| Bgee | P06795 | |
| ExpressionAtlas | P06795 | |
| Genevestigator | P06795 | |
| GO | GO:0016021 GO:0046581 GO:0005739 GO:0005886 GO:0005524 GO:0042626 GO:0008559 GO:0055085 | |
| Gene3D | 3.40.50.300 | |
| InterPro | IPR003593 IPR011527 IPR003439 IPR017871 IPR027417 | |
| Pfam | PF00664 PF00005 | |
| SMART | SM00382 | |
| SUPFAM | SSF52540 SSF90123 | |
| PROSITE | PS50929 PS00211 PS50893 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0099038 |
ceramide-translocating ATPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97570 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0090555 |
phosphatidylethanolamine-translocating ATPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97570 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0090554 |
phosphatidylcholine-translocating ATPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97570 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10613 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10613 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004513 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0061843 |
Sertoli cell barrier remodeling |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3318 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0046581 |
intercellular canaliculus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0042493 |
response to drug |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3318 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3318 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0014045 |
establishment of endothelial blood-brain barrier |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3318 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005215 |
transporter activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3318 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000139 |
Golgi membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3318 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045332 |
phospholipid translocation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0090554 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0099040 |
ceramide translocation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0099038 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003439 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Kikuchi, S et al. (2002) Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat. Genet. 31 320-5 PubMed GONUTS page
- ↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
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