Category:GO:0090555 ! phosphatidylethanolamine flippase activity

name: phosphatidylethanolamine flippase activity
namespace: molecular_function
def: "Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP." [GOC:ab, PMID:16452632, PMID:20043909, RHEA:36439]
comment: Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaflet of a membrane).
synonym: "ATP-dependent phosphatidylethanolamine transporter activity" RELATED []
synonym: "ATPase-coupled phosphatidylethanolamine transporter activity" BROAD []
synonym: "phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaflet)" EXACT []
synonym: "phosphatidylethanolamine-translocating ATPase activity" RELATED []
xref: RHEA:66132
is_a: GO:0140333 ! glycerophospholipid flippase activity

AmiGO <GOterm>GO:0090555</GOterm>
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