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MOUSE:ITSN1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Itsn1 (synonyms: Ese1, Itsn)
Protein Name(s) Intersectin-1

EH and SH3 domains protein 1

External Links
UniProt Q9Z0R4
EMBL AF132481
AF132478
AC126053
AC131691
AC134837
AF169621
AF356517
CCDS CCDS37402.1
CCDS49913.1
RefSeq NP_001103745.1
NP_034717.2
UniGene Mm.40546
PDB 3HS8
3JV3
PDBsum 3HS8
3JV3
ProteinModelPortal Q9Z0R4
SMR Q9Z0R4
BioGrid 200851
IntAct Q9Z0R4
MINT MINT-86500
STRING 10090.ENSMUSP00000066361
PhosphoSite Q9Z0R4
MaxQB Q9Z0R4
PaxDb Q9Z0R4
PRIDE Q9Z0R4
Ensembl ENSMUST00000056482
ENSMUST00000114002
GeneID 16443
KEGG mmu:16443
CTD 6453
MGI MGI:1338069
eggNOG COG5422
GeneTree ENSGT00760000118985
HOGENOM HOG000010175
HOVERGEN HBG052159
InParanoid Q9Z0R4
TreeFam TF324293
Reactome REACT_204733
REACT_209641
REACT_210090
REACT_257656
ChiTaRS Itsn1
EvolutionaryTrace Q9Z0R4
NextBio 289695
PRO PR:Q9Z0R4
Proteomes UP000000589
CleanEx MM_ITSN1
ExpressionAtlas Q9Z0R4
Genevestigator Q9Z0R4
GO GO:0030054
GO:0005905
GO:0030139
GO:0030027
GO:0043005
GO:0005886
GO:0045202
GO:0005509
GO:0019209
GO:0005089
GO:0006897
GO:0043524
GO:0042327
GO:0051897
GO:0007264
Gene3D 1.10.238.10
1.20.900.10
2.30.29.30
2.60.40.150
InterPro IPR000008
IPR000219
IPR011992
IPR018247
IPR002048
IPR000261
IPR001331
IPR001849
IPR011993
IPR001452
Pfam PF00168
PF00621
PF00018
PF14604
PRINTS PR00452
SMART SM00239
SM00054
SM00027
SM00233
SM00325
SM00326
SUPFAM SSF48065
SSF49562
SSF50044
PROSITE PS50004
PS00741
PS50010
PS00018
PS50222
PS50031
PS50003
PS50002

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043524

negative regulation of neuron apoptotic process

PMID:23054079[1]

ECO:0000314

P

Fg1 Inhibition of Intersectin-1 causes apoptotic endothelial cell death. Fg2 acute inhibition of expression causes lung micro vessel loss. Fg3 Intersectin-1 inhibitor induces lung injury. Fg4 Chronic inhibition causes significant endothelial cell death

complete
CACAO 7422

part_of

GO:0098833

presynaptic endocytic zone

PMID:23633571[2]

ECO:0006004

super-resolution microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0098833

presynaptic endocytic zone

PMID:23633571[2]

ECO:0005589

confocal microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0048488

synaptic vesicle endocytosis

PMID:18676989[3]

ECO:0006039

genetically encoded fluorescent electrophysiology assay evidence used in manual assertion

P

  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0000956)

Seeded From UniProt

complete

involved_in

GO:0048488

synaptic vesicle endocytosis

PMID:18676989[3]

ECO:0001225

knockout evidence used in manual assertion

P

  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0000956)

Seeded From UniProt

complete

part_of

GO:0044305

calyx of Held

PMID:23633571[2]

ECO:0006004

super-resolution microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0044305

calyx of Held

PMID:23633571[2]

ECO:0005589

confocal microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:2001288

positive regulation of caveolin-mediated endocytosis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1905274

regulation of modification of postsynaptic actin cytoskeleton

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

P

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

part_of

GO:0098871

postsynaptic actin cytoskeleton

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

part_of

GO:0097708

intracellular vesicle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

part_of

GO:0097440

apical dendrite

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

enables

GO:0070064

proline-rich region binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060999

positive regulation of dendritic spine development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060124

positive regulation of growth hormone secretion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

P

Seeded From UniProt

complete

enables

GO:0060090

molecular adaptor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051897

positive regulation of protein kinase B signaling

PMID:17875942[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043524

negative regulation of neuron apoptotic process

PMID:17875942[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

regulates_o_occurs_in:(CL:0000540)

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0034613

cellular protein localization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

P

Seeded From UniProt

complete

part_of

GO:0030139

endocytic vesicle

PMID:17875942[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

PMID:11744688[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0019209

kinase activator activity

PMID:17875942[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007264

small GTPase mediated signal transduction

PMID:11744688[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005905

clathrin-coated pit

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

C

Seeded From UniProt

complete

part_of

GO:0005905

clathrin-coated pit

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

colocalizes_with

GO:0005905

clathrin-coated pit

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2935

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

C

Seeded From UniProt

complete

part_of

GO:0005635

nuclear envelope

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q15811

C

Seeded From UniProt

complete

involved_in

GO:0033674

positive regulation of kinase activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0019209

P

Seeded From UniProt

complete

enables

GO:0070064

proline-rich region binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15811
ensembl:ENSP00000370719

F

Seeded From UniProt

complete

enables

GO:0060090

molecular adaptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15811
ensembl:ENSP00000370719

F

Seeded From UniProt

complete

involved_in

GO:0034613

cellular protein localization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15811
ensembl:ENSP00000370719

P

Seeded From UniProt

complete

part_of

GO:0005905

clathrin-coated pit

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15811
ensembl:ENSP00000370719

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q15811
ensembl:ENSP00000370719

C

Seeded From UniProt

complete

part_of

GO:0097440

apical dendrite

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

involved_in

GO:0060999

positive regulation of dendritic spine development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

P

Seeded From UniProt

complete

involved_in

GO:0060124

positive regulation of growth hormone secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

P

Seeded From UniProt

complete

part_of

GO:0005905

clathrin-coated pit

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

involved_in

GO:2001288

positive regulation of caveolin-mediated endocytosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

P

Seeded From UniProt

complete

involved_in

GO:1905274

regulation of modification of postsynaptic actin cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

P

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

part_of

GO:0098871

postsynaptic actin cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

part_of

GO:0097708

intracellular vesicle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WVE9
ensembl:ENSRNOP00000044773

C

Seeded From UniProt

complete

enables

GO:0005085

guanyl-nucleotide exchange factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001331

F

Seeded From UniProt

complete

enables

GO:0005089

Rho guanyl-nucleotide exchange factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000219

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002048

F

Seeded From UniProt

complete

involved_in

GO:0035023

regulation of Rho protein signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000219

P

Seeded From UniProt

complete

involved_in

GO:0035556

intracellular signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001331

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q15811-2

C

Seeded From UniProt

complete

part_of

GO:0005635

nuclear envelope

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q15811-2

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-MMU-3928643
Reactome:R-MMU-3928626
Reactome:R-MMU-3928605

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

part_of

GO:0005768

endosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0967
UniProtKB-SubCell:SL-0101

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0771
UniProtKB-SubCell:SL-0261

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006887

exocytosis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0268

P

Seeded From UniProt

complete

part_of

GO:0005905

clathrin-coated pit

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0168
UniProtKB-SubCell:SL-0069

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006897

endocytosis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0254

P

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0005635

nuclear envelope

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0178

C

Seeded From UniProt

complete

part_of

GO:0055037

recycling endosome

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0232

C

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0291

C

Seeded From UniProt

complete

part_of

GO:0012505

endomembrane system

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0147

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bardita, C et al. (2013) In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs. Apoptosis 18 57-76 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Sakaba, T et al. (2013) Fast neurotransmitter release regulated by the endocytic scaffold intersectin. Proc. Natl. Acad. Sci. U.S.A. 110 8266-71 PubMed GONUTS page
  3. 3.0 3.1 Yu, Y et al. (2008) Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities. Hum. Mol. Genet. 17 3281-90 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Das, M et al. (2007) Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway. Mol. Cell. Biol. 27 7906-17 PubMed GONUTS page
  5. 5.0 5.1 Jenna, S et al. (2002) The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin. J. Biol. Chem. 277 6366-73 PubMed GONUTS page

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Internal error - GONUTS

GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Internal error

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[d7fb8b1a965e843bd5a3423e] /wiki/index.php/MOUSE:ITSN1 Error from line 252 of /usr/local/github/wiki-extensions/wiki-extensions-hulab/AnnotationLinks/AnnotationLinks.php: Call to a member function getIdentifier() on null

Backtrace:

#0 /usr/local/github/wiki-extensions/wiki-extensions-hulab/AnnotationLinks/AnnotationLinks.php(70): AnnotationLinks::getQuickGOannotations(string, array)
#1 /var/www/html/go/wiki/includes/parser/Parser.php(3888): AnnotationLinks::renderAnnotations(NULL, array, Parser, PPFrame_DOM)
#2 /var/www/html/go/wiki/includes/parser/Preprocessor_DOM.php(1362): Parser->extensionSubstitution(array, PPFrame_DOM)
#3 /var/www/html/go/wiki/includes/parser/Parser.php(2942): PPFrame_DOM->expand(DOMElement, integer)
#4 /var/www/html/go/wiki/includes/parser/Parser.php(1293): Parser->replaceVariables(string)
#5 /var/www/html/go/wiki/includes/parser/Parser.php(443): Parser->internalParse(string)
#6 /var/www/html/go/wiki/includes/content/WikitextContent.php(323): Parser->parse(string, Title, ParserOptions, boolean, boolean, integer)
#7 /var/www/html/go/wiki/includes/content/AbstractContent.php(516): WikitextContent->fillParserOutput(Title, integer, ParserOptions, boolean, ParserOutput)
#8 /var/www/html/go/wiki/includes/content/ContentHandler.php(1324): AbstractContent->getParserOutput(Title, integer, ParserOptions)
#9 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Updater.php(348): ContentHandler->getParserOutputForIndexing(WikiPage, ParserCache)
#10 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Updater.php(407): CirrusSearch\Updater::buildDocument(CirrusSearch, WikiPage, CirrusSearch\Connection, integer, integer, integer)
#11 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Updater.php(205): CirrusSearch\Updater->buildDocumentsForPages(array, integer)
#12 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Updater.php(83): CirrusSearch\Updater->updatePages(array, integer)
#13 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Job/LinksUpdate.php(52): CirrusSearch\Updater->updateFromTitle(Title)
#14 /usr/local/github/wiki-extensions/wiki-extensions-hulab/CirrusSearch/includes/Job/Job.php(99): CirrusSearch\Job\LinksUpdate->doJob()
#15 /var/www/html/go/wiki/includes/jobqueue/JobRunner.php(296): CirrusSearch\Job\Job->run()
#16 /var/www/html/go/wiki/includes/jobqueue/JobRunner.php(193): JobRunner->executeJob(CirrusSearch\Job\LinksUpdate, Wikimedia\Rdbms\LBFactorySimple, BufferingStatsdDataFactory, integer)
#17 /var/www/html/go/wiki/includes/MediaWiki.php(1002): JobRunner->run(array)
#18 /var/www/html/go/wiki/includes/MediaWiki.php(988): MediaWiki->triggerSyncJobs(integer, MediaWiki\Logger\LegacyLogger)
#19 /var/www/html/go/wiki/includes/MediaWiki.php(912): MediaWiki->triggerJobs()
#20 /var/www/html/go/wiki/includes/MediaWiki.php(727): MediaWiki->restInPeace(string, boolean)
#21 /var/www/html/go/wiki/includes/MediaWiki.php(750): MediaWiki->{closure}()
#22 /var/www/html/go/wiki/includes/MediaWiki.php(557): MediaWiki->doPostOutputShutdown(string)
#23 /var/www/html/go/wiki/index.php(42): MediaWiki->run()
#24 {main}

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