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MOUSE:IFI2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Ifi202 (synonyms: Ifi202a, Ifi202b) | |
| Protein Name(s) | Interferon-activable protein 202
Ifi-202 Interferon-inducible protein p202 Lupus susceptibility protein p202 | |
| External Links | ||
| UniProt | Q9R002 | |
| EMBL | M31418 AF140672 DQ222946 AC170584 BC018233 BC055888 | |
| CCDS | CCDS35794.1 | |
| PIR | A34457 | |
| RefSeq | NP_032353.2 NP_036070.2 XP_001473923.2 XP_006536966.1 | |
| UniGene | Mm.218770 | |
| PDB | 4JBJ 4JBK 4L5Q 4L5R 4L5S 4L5T 4LNQ | |
| PDBsum | 4JBJ 4JBK 4L5Q 4L5R 4L5S 4L5T 4LNQ | |
| ProteinModelPortal | Q9R002 | |
| SMR | Q9R002 | |
| BioGrid | 204945 | |
| IntAct | Q9R002 | |
| MINT | MINT-4098521 | |
| PhosphoSite | Q9R002 | |
| PaxDb | Q9R002 | |
| PRIDE | Q9R002 | |
| Ensembl | ENSMUST00000000266 | |
| GeneID | 100044068 26388 | |
| KEGG | mmu:100044068 mmu:26388 | |
| UCSC | uc007dsk.2 | |
| CTD | 26388 | |
| MGI | MGI:1347080 MGI:1347083 | |
| eggNOG | NOG81691 | |
| GeneTree | ENSGT00390000013296 | |
| InParanoid | Q9R002 | |
| KO | K12971 | |
| OrthoDB | EOG7ZD1V8 | |
| TreeFam | TF337385 | |
| ChiTaRS | Ifi202b | |
| NextBio | 304323 | |
| PRO | PR:Q9R002 | |
| Proteomes | UP000000589 | |
| Bgee | Q9R002 | |
| CleanEx | MM_IFI202B | |
| Genevestigator | Q9R002 | |
| GO | GO:0005737 GO:0005634 GO:0003690 GO:0006954 GO:0045087 GO:0043154 GO:0045824 | |
| Gene3D | 2.40.50.140 | |
| InterPro | IPR004021 IPR012340 | |
| Pfam | PF02760 | |
| PROSITE | PS50834 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0010628 |
positive regulation of gene expression |
ECO:0000314 |
P |
Fig. 5 |
complete | |||||
|
involved_in |
GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003690 |
double-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003690 |
double-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0035458 |
cellular response to interferon-beta |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002218 |
activation of innate immune response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035458 |
cellular response to interferon-beta |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045824 |
negative regulation of innate immune response |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045087 |
innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002376 |
immune system process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Panchanathan, R & Choubey, D (2013) Murine BAFF expression is up-regulated by estrogen and interferons: implications for sex bias in the development of autoimmunity. Mol. Immunol. 53 15-23 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Roberts, TL et al. (2009) HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323 1057-60 PubMed GONUTS page
- ↑ Ru, H et al. (2013) Structural basis for termination of AIM2-mediated signaling by p202. Cell Res. 23 855-8 PubMed GONUTS page
- ↑ Bürckstümmer, T et al. (2009) An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat. Immunol. 10 266-72 PubMed GONUTS page
