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MOUSE:HYAS3
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Has3 | |
| Protein Name(s) | Hyaluronan synthase 3
Hyaluronate synthase 3 Hyaluronic acid synthase 3 HA synthase 3 | |
| External Links | ||
| UniProt | O08650 | |
| EMBL | U86408 AK028582 BC138152 | |
| CCDS | CCDS22640.1 | |
| RefSeq | NP_032243.2 XP_006530762.1 XP_006530763.1 XP_006530764.1 | |
| UniGene | Mm.56986 | |
| ProteinModelPortal | O08650 | |
| STRING | 10090.ENSMUSP00000034385 | |
| CAZy | GT2 | |
| PhosphoSite | O08650 | |
| PaxDb | O08650 | |
| PRIDE | O08650 | |
| Ensembl | ENSMUST00000034385 ENSMUST00000176144 | |
| GeneID | 15118 | |
| KEGG | mmu:15118 | |
| UCSC | uc009ngn.2 | |
| CTD | 3038 | |
| MGI | MGI:109599 | |
| eggNOG | KOG2571 COG1215 | |
| GeneTree | ENSGT00390000010337 | |
| HOGENOM | HOG000112847 | |
| HOVERGEN | HBG000189 | |
| InParanoid | O08650 | |
| KO | K00752 | |
| OMA | RGRLWNI | |
| OrthoDB | EOG77WWBZ | |
| TreeFam | TF332506 | |
| BRENDA | 2.4.1.212 | |
| Reactome | [www.reactome.org/content/detail/R-MMU-2142850 R-MMU-2142850] | |
| UniPathway | UPA00341 | |
| PRO | PR:O08650 | |
| Proteomes | UP000000589 | |
| Bgee | O08650 | |
| CleanEx | MM_HAS3 | |
| ExpressionAtlas | O08650 | |
| Genevisible | O08650 | |
| GO | GO:0005737 GO:0036117 GO:0016021 GO:0050501 GO:0085029 GO:0045226 GO:0030213 GO:1900106 GO:0045893 | |
| Gene3D | 3.90.550.10 | |
| InterPro | IPR026108 IPR026107 IPR029044 | |
| PANTHER | PTHR22913 PTHR22913:SF6 | |
| SUPFAM | SSF53448 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
Figures 1,2,3,4 |
complete | |||||
| GO:0005634 |
nucleus |
ECO:0000314 |
C |
Figure 7 |
complete | |||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0085029 |
extracellular matrix assembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045226 |
extracellular polysaccharide biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0085029 |
extracellular matrix assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045226 |
extracellular polysaccharide biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000530809 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1900106 |
positive regulation of hyaluranon cable assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0036117 |
hyaluranon cable |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1900106 |
positive regulation of hyaluranon cable assembly |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00219 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00219 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00219 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00219 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0036117 |
hyaluranon cable |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00219 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00219 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00341 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Törrönen, K et al. (2014) Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes. Histochem. Cell Biol. 141 17-31 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Itano, N et al. (1999) Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J. Biol. Chem. 274 25085-92 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 Hoock, TC et al. (1997) Isoforms of ankyrin-3 that lack the NH2-terminal repeats associate with mouse macrophage lysosomes. J. Cell Biol. 136 1059-70 PubMed GONUTS page
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