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MOUSE:HPT

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Hp
Protein Name(s) Haptoglobin

Zonulin Haptoglobin alpha chain Haptoglobin beta chain

External Links
UniProt Q61646
EMBL M96827
CCDS CCDS40470.1
RefSeq NP_059066.1
UniGene Mm.26730
ProteinModelPortal Q61646
SMR Q61646
IntAct Q61646
MINT MINT-1870167
MEROPS S01.972
PhosphoSite Q61646
MaxQB Q61646
PaxDb Q61646
PRIDE Q61646
Ensembl ENSMUST00000074898
GeneID 15439
KEGG mmu:15439
UCSC uc009nin.2
CTD 3240
MGI MGI:96211
eggNOG NOG246387
GeneTree ENSGT00760000118890
HOGENOM HOG000112945
HOVERGEN HBG005989
InParanoid Q61646
KO K16142
OMA DDTWYAA
OrthoDB EOG722J8R
PhylomeDB Q61646
TreeFam TF334326
Reactome REACT_196575
ChiTaRS Hp
NextBio 288222
PRO PR:Q61646
Proteomes UP000000589
Bgee Q61646
CleanEx MM_HP
ExpressionAtlas Q61646
Genevestigator Q61646
GO GO:0005783
GO:0005615
GO:0005794
GO:0016209
GO:0003824
GO:0006953
GO:0042742
GO:0002376
GO:0001889
GO:0031100
GO:0033590
GO:0042493
GO:0051602
GO:0051384
GO:0009408
GO:0001666
GO:0033591
GO:0010288
GO:0032496
GO:0032026
GO:0010165
GO:0007283
InterPro IPR008292
IPR001254
IPR001314
IPR000436
IPR009003
Pfam PF00089
PIRSF PIRSF001137
PRINTS PR00722
SMART SM00032
SM00020
SUPFAM SSF50494
SSF57535
PROSITE PS50923
PS50240

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005615

extracellular space

PMID:24006456[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

produced_by:(CL:0002548)

Seeded From UniProt

complete

involved_in

GO:0010942

positive regulation of cell death

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000667778
UniProtKB:P00738

P

Seeded From UniProt

complete

involved_in

GO:0010033

response to organic substance

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000667778
RGD:2825

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2660692
MGI:MGI:88492
PANTHER:PTN001207255
RGD:2825
RGD:620213
UniProtKB:P00736
UniProtKB:P00738
UniProtKB:P48740

C

Seeded From UniProt

complete

enables

GO:0004252

serine-type endopeptidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88492
PANTHER:PTN001207255
RGD:620213
RGD:620214
UniProtKB:O00187
UniProtKB:P00736
UniProtKB:P09871
UniProtKB:P48740

F

Seeded From UniProt

complete

involved_in

GO:0002526

acute inflammatory response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000667778
RGD:2825

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:2000296

negative regulation of hydrogen peroxide catabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

P

Seeded From UniProt

complete

part_of

GO:0072562

blood microparticle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051354

negative regulation of oxidoreductase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042542

response to hydrogen peroxide

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

P

Seeded From UniProt

complete

part_of

GO:0031838

haptoglobin-hemoglobin complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

C

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

F

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010942

positive regulation of cell death

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0009617

response to bacterium

PMID:23012479[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007219

Notch signaling pathway

PMID:23117660[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P00738

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001889

liver development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2825

P

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004252

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016209

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008292

C

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008292

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

enables

GO:0016209

antioxidant activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0049

F

Seeded From UniProt

complete

involved_in

GO:0006953

acute-phase response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0011

P

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0351

F

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0044

P

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Abonnenc, M et al. (2013) Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ. Res. 113 1138-47 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. ↑ Archambaud, C et al. (2012) Impact of lactobacilli on orally acquired listeriosis. Proc. Natl. Acad. Sci. U.S.A. 109 16684-9 PubMed GONUTS page
  4. ↑ Fouillade, C et al. (2013) Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature. Arterioscler. Thromb. Vasc. Biol. 33 76-86 PubMed GONUTS page
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