MOUSE:EDNRB

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Ednrb
Protein Name(s)	Endothelin B receptor ET-B ET-BR Endothelin receptor non-selective type
External Links
UniProt	P48302
EMBL	U32329 AK076426 AK082103 AK083415 AK085532 BC026553
CCDS	CCDS27317.1
RefSeq	NP_001129533.1 NP_001263225.1 NP_031930.1 XP_006518578.1
UniGene	Mm.229532
ProteinModelPortal	P48302
SMR	P48302
BindingDB	P48302
ChEMBL	CHEMBL1681617
GuidetoPHARMACOLOGY	220
PhosphoSite	P48302
MaxQB	P48302
PaxDb	P48302
PRIDE	P48302
Ensembl	ENSMUST00000022718 ENSMUST00000172237
GeneID	13618
KEGG	mmu:13618
UCSC	uc007uww.2
CTD	1910
MGI	MGI:102720
eggNOG	NOG278704
GeneTree	ENSGT00760000119177
HOGENOM	HOG000272623
HOVERGEN	HBG051443
InParanoid	P48302
KO	K04198
OMA	TAEIMTP
OrthoDB	EOG7HHWS4
PhylomeDB	P48302
TreeFam	TF331292
Reactome	REACT_207651 REACT_235286
ChiTaRS	Ednrb
NextBio	284288
PRO	PR:P48302
Proteomes	UP000000589
Bgee	P48302
CleanEx	MM_EDNRB
Genevestigator	P48302
GO	GO:0016021 GO:0045121 GO:0031965 GO:0005886 GO:0004962 GO:0017046 GO:0007568 GO:0071222 GO:0019934 GO:0048066 GO:0086100 GO:0048484 GO:0035645 GO:0042045 GO:0007186 GO:0048246 GO:0030318 GO:0043066 GO:0032269 GO:0014043 GO:0000122 GO:0001755 GO:0007422 GO:0007200 GO:0043473 GO:0008284 GO:0007204 GO:0060406 GO:0001934 GO:0035815 GO:0035810 GO:0007497 GO:0008217 GO:0050678 GO:0031620 GO:0006885 GO:0051930 GO:0014070 GO:0048265 GO:0019233 GO:0042311 GO:0014826
InterPro	IPR000499 IPR001112 IPR000276 IPR017452
Pfam	PF00001
PRINTS	PR00571 PR00366 PR00237
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005515	protein binding		ECO:0000021			F		Source: MGI	Missing: with/from, reference
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P24530	C		Seeded From UniProt	complete
involved_in	GO:0019722	calcium-mediated signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
involved_in	GO:0048484	enteric nervous system development	PMID:10021336^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035645	enteric smooth muscle cell differentiation	PMID:10021336^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0014043	negative regulation of neuron maturation	PMID:10021336^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:10021336^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	PMID:12441350^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	F		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001755	neural crest cell migration	PMID:10591209^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(EMAPA:16247) results_in_movement_of:(CL:0000031)\|results_in_movement_of:(CL:0000541)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1990839	response to endothelin	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0086100	endothelin receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060406	positive regulation of penile erection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051930	regulation of sensory perception of pain	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050678	regulation of epithelial cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048484	enteric nervous system development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048265	response to pain	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048246	macrophage chemotaxis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048066	developmental pigmentation	PMID:15322542^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1856149	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043473	pigmentation	PMID:2379821^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1856148	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043473	pigmentation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042311	vasodilation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042310	vasoconstriction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042310	vasoconstriction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042045	epithelial fluid transport	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035815	positive regulation of renal sodium excretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035810	positive regulation of urine volume	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032496	response to lipopolysaccharide	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032269	negative regulation of cellular protein metabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	C		Seeded From UniProt	complete
enables	GO:0031702	type 1 angiotensin receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031620	regulation of fever generation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030318	melanocyte differentiation	PMID:2379821^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1856148	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030318	melanocyte differentiation	PMID:9012511^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030318	melanocyte differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019934	cGMP-mediated signaling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019722	calcium-mediated signaling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019233	sensory perception of pain	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
enables	GO:0017046	peptide hormone binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014826	vein smooth muscle contraction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008217	regulation of blood pressure	PMID:10626068^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857161	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008217	regulation of blood pressure	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007497	posterior midgut development	PMID:8582288^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1856149	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007422	peripheral nervous system development	PMID:8582288^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1856149	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007186	G protein-coupled receptor signaling pathway	PMID:12441350^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95768	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007186	G protein-coupled receptor signaling pathway	PMID:12441350^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006885	regulation of pH	PMID:11413164^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857161	P	has_participant:(EMAPA:16332)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P24530	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2536	C		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	PMID:11413164^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857161	F	occurs_in:(EMAPA:28287)	Seeded From UniProt	complete
involved_in	GO:1990839	response to endothelin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0071222	cellular response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0060406	positive regulation of penile erection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0051930	regulation of sensory perception of pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0050678	regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0048484	enteric nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0048265	response to pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	C		Seeded From UniProt	complete
involved_in	GO:0043473	pigmentation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0042311	vasodilation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0042310	vasoconstriction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0042045	epithelial fluid transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0035815	positive regulation of renal sodium excretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0035810	positive regulation of urine volume	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0032496	response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
part_of	GO:0031965	nuclear membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	C		Seeded From UniProt	complete
enables	GO:0031702	type 1 angiotensin receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	F		Seeded From UniProt	complete
involved_in	GO:0031620	regulation of fever generation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0030318	melanocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0019934	cGMP-mediated signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0019233	sensory perception of pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	C		Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0008217	regulation of blood pressure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0007568	aging	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	C		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	F		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21451 ensembl:ENSRNOP00000014747	P		Seeded From UniProt	complete
involved_in	GO:0086100	endothelin receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
involved_in	GO:0048246	macrophage chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
involved_in	GO:0042310	vasoconstriction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
involved_in	GO:0032269	negative regulation of cellular protein metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
involved_in	GO:0019722	calcium-mediated signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
enables	GO:0017046	peptide hormone binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	F		Seeded From UniProt	complete
involved_in	GO:0014826	vein smooth muscle contraction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	C		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	F		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24530 ensembl:ENSP00000366416	P		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F		Seeded From UniProt	complete
enables	GO:0004962	endothelin receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000499 InterPro:IPR001112	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR000499 InterPro:IPR001112	P		Seeded From UniProt	complete
involved_in	GO:0008217	regulation of blood pressure	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000499 InterPro:IPR001112	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR000499 InterPro:IPR001112 InterPro:IPR017452	C		Seeded From UniProt	complete
involved_in	GO:0042310	vasoconstriction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000499 InterPro:IPR001112	P		Seeded From UniProt	complete
involved_in	GO:0048484	enteric nervous system development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000499 InterPro:IPR001112	P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Wu, JJ et al. (1999) Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors. Development 126 1161-73 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Liu, B & Wu, D (2003) The first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13. J. Biol. Chem. 278 2384-7 PubMed GONUTS page
↑ Shin, MK et al. (1999) The temporal requirement for endothelin receptor-B signalling during neural crest development. Nature 402 496-501 PubMed GONUTS page
↑ Van Raamsdonk, CD et al. (2004) Effects of G-protein mutations on skin color. Nat. Genet. 36 961-8 PubMed GONUTS page
↑ ^5.0 ^5.1 Moore, KJ et al. (1990) Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations. Genetics 125 421-30 PubMed GONUTS page
↑ Reid, K et al. (1996) Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation. Development 122 3911-9 PubMed GONUTS page
↑ Kuwaki, T et al. (1999) Endothelin in the central control of cardiovascular and respiratory functions. Clin. Exp. Pharmacol. Physiol. 26 989-94 PubMed GONUTS page
↑ ^8.0 ^8.1 Kapur, RP et al. (1995) Intercellular signals downstream of endothelin receptor-B mediate colonization of the large intestine by enteric neuroblasts. Development 121 3787-95 PubMed GONUTS page
↑ ^9.0 ^9.1 Laghmani, K et al. (2001) Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis. J. Clin. Invest. 107 1563-9 PubMed GONUTS page

[PMID:10021336-1] 1.0 ^1.1 ^1.2 ^1.3 Wu, JJ et al. (1999) Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors. Development 126 1161-73 PubMed GONUTS page

[PMID:12441350-2] 2.0 ^2.1 ^2.2 Liu, B & Wu, D (2003) The first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13. J. Biol. Chem. 278 2384-7 PubMed GONUTS page

[PMID:10591209-3] Shin, MK et al. (1999) The temporal requirement for endothelin receptor-B signalling during neural crest development. Nature 402 496-501 PubMed GONUTS page

[PMID:15322542-4] Van Raamsdonk, CD et al. (2004) Effects of G-protein mutations on skin color. Nat. Genet. 36 961-8 PubMed GONUTS page

[PMID:2379821-5] 5.0 ^5.1 Moore, KJ et al. (1990) Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations. Genetics 125 421-30 PubMed GONUTS page

[PMID:9012511-6] Reid, K et al. (1996) Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation. Development 122 3911-9 PubMed GONUTS page

[PMID:10626068-7] Kuwaki, T et al. (1999) Endothelin in the central control of cardiovascular and respiratory functions. Clin. Exp. Pharmacol. Physiol. 26 989-94 PubMed GONUTS page

[PMID:8582288-8] 8.0 ^8.1 Kapur, RP et al. (1995) Intercellular signals downstream of endothelin receptor-B mediate colonization of the large intestine by enteric neuroblasts. Development 121 3787-95 PubMed GONUTS page

[PMID:11413164-9] 9.0 ^9.1 Laghmani, K et al. (2001) Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis. J. Clin. Invest. 107 1563-9 PubMed GONUTS page

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