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MOUSE:DEN5B

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Dennd5b
Protein Name(s) DENN domain-containing protein 5B

Rab6IP1-like protein

External Links
UniProt A2RSQ0
EMBL AC132412
AC140327
AK050728
AK052296
BC132199
BC132535
CCDS CCDS20714.2
RefSeq NP_796166.2
UniGene Mm.426874
ProteinModelPortal A2RSQ0
SMR A2RSQ0
STRING 10090.ENSMUSP00000107182
iPTMnet A2RSQ0
PhosphoSitePlus A2RSQ0
jPOST A2RSQ0
MaxQB A2RSQ0
PaxDb A2RSQ0
PeptideAtlas A2RSQ0
PRIDE A2RSQ0
Ensembl ENSMUST00000111557
GeneID 320560
KEGG mmu:320560
UCSC uc009ett.1
CTD 160518
MGI MGI:2444273
eggNOG KOG2080
ENOG410XNYP
GeneTree ENSGT00940000153678
HOGENOM HOG000019389
HOVERGEN HBG059906
InParanoid A2RSQ0
KO K20164
OMA LGKQCRT
OrthoDB 53600at2759
PhylomeDB A2RSQ0
TreeFam TF313237
Reactome R-MMU-8876198
PRO PR:A2RSQ0
Proteomes UP000000589
Bgee ENSMUSG00000030313
ExpressionAtlas A2RSQ0
Genevisible A2RSQ0
GO GO:0016021
GO:0017112
InterPro IPR001194
IPR005112
IPR001024
IPR036392
IPR004012
IPR037213
IPR037516
IPR005113
Pfam PF03455
PF02141
PF01477
PF02759
PF03456
SMART SM00801
SM00799
SM00593
SM00800
SUPFAM SSF140741
SSF49723
PROSITE PS50211
PS50095
PS50826

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1905885

positive regulation of triglyceride transport

PMID:30837651[1]

ECO:0005601

immunofluorescence confocal microscopy evidence used in manual assertion

P

In Figure 2G, there is a significant absence of apoB in dennd5b -/- mice, a protein required for enterocyte absorption of triglycerides (lipids), compared to dennd5b+/+ mice.

complete
CACAO 13557

enables

GO:0017112

Rab guanyl-nucleotide exchange factor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6IQ26

F

Seeded From UniProt

complete

enables

GO:0017112

Rab guanyl-nucleotide exchange factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6ZUT9

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0005085

guanyl-nucleotide exchange factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0344

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gordon, SM et al. (2019) DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass. Sci Rep 9 3597 PubMed GONUTS page