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HUMAN:ZN395

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ZNF395 (synonyms: HDBP2, PBF)
Protein Name(s) Zinc finger protein 395

HD-regulating factor 2 HDRF-2 Huntington disease gene regulatory region-binding protein 2 HD gene regulatory region-binding protein 2 HDBP-2 Papillomavirus regulatory factor 1 PRF-1 Papillomavirus-binding factor

External Links
UniProt Q9H8N7
EMBL AF263928
AB044750
AB044751
AB044752
AB057659
AB073627
AK002050
AK023418
AK098243
CH471080
CH471080
CH471080
CH471080
CH471080
BC001237
CCDS CCDS6067.1
RefSeq NP_061130.1
UniGene Hs.435535
Hs.695998
ProteinModelPortal Q9H8N7
BioGrid 120983
IntAct Q9H8N7
MINT MINT-7997332
STRING 9606.ENSP00000340494
PhosphoSite Q9H8N7
BioMuta ZNF395
DMDM 84028224
MaxQB Q9H8N7
PaxDb Q9H8N7
PRIDE Q9H8N7
DNASU 55893
Ensembl ENST00000344423
ENST00000523095
ENST00000523202
GeneID 55893
KEGG hsa:55893
UCSC uc003xgq.3
CTD 55893
GeneCards GC08M028203
HGNC HGNC:18737
HPA HPA049382
MIM 609494
neXtProt NX_Q9H8N7
PharmGKB PA134978145
eggNOG NOG69635
GeneTree ENSGT00400000022069
HOVERGEN HBG061238
InParanoid Q9H8N7
OMA VWYGGQE
OrthoDB EOG7FFMS0
PhylomeDB Q9H8N7
TreeFam TF326610
ChiTaRS ZNF395
GenomeRNAi 55893
NextBio 61241
PRO PR:Q9H8N7
Proteomes UP000005640
Bgee Q9H8N7
CleanEx HS_ZNF395
ExpressionAtlas Q9H8N7
Genevisible Q9H8N7
GO GO:0005737
GO:0005634
GO:0003677
GO:0046872
GO:0000978
GO:0006355
GO:0006351
InterPro IPR007087
IPR015880
SMART SM00355
PROSITE PS00028
PS50157

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:14625278[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:14625278[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:14625278[2]

ECO:0000305

curator inference used in manual assertion

GO:0003677

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:14625278[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:14625278[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:14625278[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:E9Q5N9
ensembl:ENSMUSP00000064422

P

Seeded From UniProt

complete

enables

GO:0001158

enhancer sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:E9Q5N9
ensembl:ENSMUSP00000064422

F

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013087

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Tanaka, K et al. (2004) Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene. J. Biol. Chem. 279 7275-86 PubMed GONUTS page