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HUMAN:ZCHC8
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ZCCHC8 | |
| Protein Name(s) | Zinc finger CCHC domain-containing protein 8
TRAMP-like complex RNA-binding factor ZCCHC8 | |
| External Links | ||
| UniProt | Q6NZY4 | |
| EMBL | AK027702 AK074638 AL157433 AL157434 BC017704 BC065918 | |
| PIR | T46929 T46930 | |
| RefSeq | NP_060082.2 XP_005253638.1 XP_006719555.1 | |
| UniGene | Hs.37706 | |
| ProteinModelPortal | Q6NZY4 | |
| BioGrid | 120739 | |
| IntAct | Q6NZY4 | |
| MINT | MINT-1187494 | |
| STRING | 9606.ENSP00000337313 | |
| PhosphoSite | Q6NZY4 | |
| DMDM | 66774213 | |
| MaxQB | Q6NZY4 | |
| PaxDb | Q6NZY4 | |
| PRIDE | Q6NZY4 | |
| Ensembl | ENST00000536306 ENST00000543897 | |
| GeneID | 55596 | |
| KEGG | hsa:55596 | |
| UCSC | uc001ucm.3 | |
| CTD | 55596 | |
| GeneCards | GC12M122958 | |
| H-InvDB | HIX0011095 | |
| HGNC | HGNC:25265 | |
| HPA | HPA037483 HPA037484 | |
| neXtProt | NX_Q6NZY4 | |
| PharmGKB | PA134889410 | |
| eggNOG | NOG242619 | |
| GeneTree | ENSGT00390000011475 | |
| HOGENOM | HOG000155769 | |
| HOVERGEN | HBG079371 | |
| InParanoid | Q6NZY4 | |
| KO | K13128 | |
| OMA | CEETIEQ | |
| OrthoDB | EOG7RNK09 | |
| PhylomeDB | Q6NZY4 | |
| TreeFam | TF321837 | |
| ChiTaRS | ZCCHC8 | |
| GeneWiki | ZCCHC8 | |
| GenomeRNAi | 55596 | |
| NextBio | 60130 | |
| PMAP-CutDB | Q6NZY4 | |
| PRO | PR:Q6NZY4 | |
| Proteomes | UP000005640 | |
| Bgee | Q6NZY4 | |
| CleanEx | HS_ZCCHC8 | |
| ExpressionAtlas | Q6NZY4 | |
| Genevestigator | Q6NZY4 | |
| GO | GO:0071013 GO:0005654 GO:0005634 GO:0044822 GO:0008270 GO:0000398 | |
| Gene3D | 4.10.60.10 | |
| InterPro | IPR006568 IPR001878 | |
| Pfam | PF04046 PF00098 | |
| SMART | SM00581 SM00343 | |
| PROSITE | PS50158 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0031499 |
TRAMP complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
NOT|part_of |
GO:0005730 |
nucleolus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0071013 |
catalytic step 2 spliceosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000398 |
mRNA splicing, via spliceosome |
ECO:0000305 |
curator inference used in manual assertion |
GO:0071013 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016604 |
nuclear body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008380 |
RNA splicing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005681 |
spliceosomal complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006397 |
mRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Lubas, M et al. (2011) Interaction profiling identifies the human nuclear exosome targeting complex. Mol. Cell 43 624-37 PubMed GONUTS page
- ↑ Gustafson, MP et al. (2005) Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins. Biochem. Biophys. Res. Commun. 338 1359-67 PubMed GONUTS page
- ↑ 3.0 3.1 Jurica, MS et al. (2002) Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8 426-39 PubMed GONUTS page
- ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
