GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0031499 ! TRAMP complex
name: TRAMP complex
namespace: cellular_component
def: "A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control." [PMID:15173578, PMID:15828860, PMID:15935758, PMID:15935759, PMID:16373491, PMID:16374505, PMID:16431988, PMID:16973437, PMID:17410208, PMID:17652137]
synonym: "TRAMP4 complex" NARROW []
synonym: "TRAMP5 complex" NARROW []
synonym: "Trf4 complex" NARROW []
synonym: "Trf4 poly(A) polymerase complex" NARROW []
synonym: "Trf4p-Air2p-Mtr4p polyadenylation complex" NARROW []
xref: Wikipedia:TRAMP_complex
is_a: GO:0140513 ! nuclear protein-containing complex
AmiGO
<GOterm>GO:0031499</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
