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HUMAN:VSIG4

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) VSIG4 (synonyms: CRIg, Z39IG)
Protein Name(s) V-set and immunoglobulin domain-containing protein 4

Protein Z39Ig

External Links
UniProt Q9Y279
EMBL AJ132502
AY358341
AL034397
CR607860
BC010525
CCDS CCDS14383.1
CCDS48132.1
CCDS55435.1
RefSeq NP_001093901.1
NP_001171759.1
NP_001171760.1
NP_001244332.1
NP_009199.1
UniGene Hs.8904
PDB 2ICC
2ICE
2ICF
PDBsum 2ICC
2ICE
2ICF
ProteinModelPortal Q9Y279
SMR Q9Y279
BioGrid 116455
IntAct Q9Y279
STRING 9606.ENSP00000363869
PhosphoSite Q9Y279
DMDM 59799152
PaxDb Q9Y279
PRIDE Q9Y279
DNASU 11326
Ensembl ENST00000374737
ENST00000412866
ENST00000455586
GeneID 11326
KEGG hsa:11326
UCSC uc004dwh.2
uc004dwi.2
CTD 11326
GeneCards GC0XM065241
HGNC HGNC:17032
HPA CAB026000
HPA003903
MIM 300353
neXtProt NX_Q9Y279
PharmGKB PA134986421
eggNOG NOG39012
GeneTree ENSGT00390000001432
HOGENOM HOG000137602
HOVERGEN HBG055008
InParanoid Q9Y279
OMA TYGHPIL
PhylomeDB Q9Y279
TreeFam TF336175
EvolutionaryTrace Q9Y279
GenomeRNAi 11326
NextBio 43025
PRO PR:Q9Y279
Proteomes UP000005640
Bgee Q9Y279
CleanEx HS_VSIG4
Genevestigator Q9Y279
GO GO:0070062
GO:0016021
GO:0006957
GO:0032703
GO:0042130
Gene3D 2.60.40.10
InterPro IPR007110
IPR013783
IPR003599
IPR003598
IPR013106
Pfam PF07686
SMART SM00409
SM00408
PROSITE PS50835

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0032991

protein-containing complex

PMID:17051150[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P01024

C

Seeded From UniProt

complete

involved_in

GO:0045957

negative regulation of complement activation, alternative pathway

PMID:17051150[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P01024

P

Seeded From UniProt

complete

enables

GO:0001851

complement component C3b binding

PMID:17051150[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P01024

F

Seeded From UniProt

complete

involved_in

GO:0032703

negative regulation of interleukin-2 production

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039939

P

Seeded From UniProt

complete

involved_in

GO:0042130

negative regulation of T cell proliferation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039939

P

Seeded From UniProt

complete

involved_in

GO:0043031

negative regulation of macrophage activation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039939

P

Seeded From UniProt

complete

involved_in

GO:0006957

complement activation, alternative pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0179

P

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Wiesmann, C et al. (2006) Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature 444 217-20 PubMed GONUTS page