HUMAN:SPN90

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	NCKIPSD (synonyms: AF3P21, SPIN90)
Protein Name(s)	NCK-interacting protein with SH3 domain 54 kDa VacA-interacting protein 54 kDa vimentin-interacting protein VIP54 90 kDa SH3 protein interacting with Nck AF3p21 Dia-interacting protein 1 DIP-1 Diaphanous protein-interacting protein SH3 adapter protein SPIN90 WASP-interacting SH3-domain protein WISH Wiskott-Aldrich syndrome protein-interacting protein
External Links
UniProt	Q9NZQ3
EMBL	AF178432 AJ242655 AF303581 AB069981 AB069982 AY453794 AC141002 BC016052 BC026280 AK294151
CCDS	CCDS2776.1 CCDS46827.1
RefSeq	NP_057537.1 NP_909119.1
UniGene	Hs.655006
ProteinModelPortal	Q9NZQ3
SMR	Q9NZQ3
BioGrid	119583
IntAct	Q9NZQ3
MINT	MINT-1438080
STRING	9606.ENSP00000294129
PhosphoSite	Q9NZQ3
DMDM	17433253
MaxQB	Q9NZQ3
PaxDb	Q9NZQ3
PRIDE	Q9NZQ3
DNASU	51517
Ensembl	ENST00000294129 ENST00000416649
GeneID	51517
KEGG	hsa:51517
UCSC	uc003cum.3 uc003cun.3
CTD	51517
GeneCards	GC03M048701
HGNC	HGNC:15486
HPA	CAB019267
MIM	606671
neXtProt	NX_Q9NZQ3
PharmGKB	PA134872724
eggNOG	NOG283973
GeneTree	ENSGT00390000015725
HOGENOM	HOG000008184
HOVERGEN	HBG061630
InParanoid	Q9NZQ3
OMA	FRSSEPN
OrthoDB	EOG7966G7
PhylomeDB	Q9NZQ3
TreeFam	TF324522
Reactome	REACT_160086
SignaLink	Q9NZQ3
ChiTaRS	NCKIPSD
GeneWiki	NCKIPSD
GenomeRNAi	51517
NextBio	55214
PRO	PR:Q9NZQ3
Proteomes	UP000005640
Bgee	Q9NZQ3
CleanEx	HS_NCKIPSD
ExpressionAtlas	Q9NZQ3
Genevestigator	Q9NZQ3
GO	GO:0005829 GO:0005882 GO:0005634 GO:0008092 GO:0007010 GO:0038096 GO:0045087 GO:0006607 GO:0007165
InterPro	IPR018556 IPR001452
Pfam	PF09431 PF00018
SMART	SM00326
SUPFAM	SSF50044
PROSITE	PS50002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0043197	dendritic spine	PMID:23342115	ECO:0000314			C		Figure 1 - Phosphorylated SPIN90 is localized to spines in neurons.	complete
colocalizes_with	GO:0008180	COP9 signalosome	PMID:18850735	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0008092	cytoskeletal protein binding	PMID:10619843	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007010	cytoskeleton organization	PMID:10619843	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005882	intermediate filament	PMID:10619843	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010976	positive regulation of neuron projection development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9ESJ4 ensembl:ENSMUSP00000035218	P		Seeded From UniProt	complete
involved_in	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	Reactome:R-HSA-2029480	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-2197698 Reactome:R-HSA-2197691 Reactome:R-HSA-2197690 Reactome:R-HSA-2029466	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0729	F		Seeded From UniProt	complete
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References

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