HUMAN:RN112

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	RNF112 (synonyms: BFP, ZNF179)
Protein Name(s)	RING finger protein 112 Brain finger protein Zinc finger protein 179
External Links
UniProt	Q9ULX5
EMBL	AB026054 AC004448 BC053989 AF054587
CCDS	CCDS58529.1
PIR	JC7155
RefSeq	NP_009079.2
UniGene	Hs.189482
ProteinModelPortal	Q9ULX5
SMR	Q9ULX5
STRING	9606.ENSP00000299604
PhosphoSite	Q9ULX5
DMDM	378405197
MaxQB	Q9ULX5
PaxDb	Q9ULX5
PRIDE	Q9ULX5
DNASU	7732
Ensembl	ENST00000461366
GeneID	7732
KEGG	hsa:7732
UCSC	uc010vyw.2
CTD	7732
GeneCards	GC17P019314
HGNC	HGNC:12968
HPA	HPA015970
MIM	601237
neXtProt	NX_Q9ULX5
eggNOG	NOG282667
GeneTree	ENSGT00390000008959
HOVERGEN	HBG056662
InParanoid	Q9ULX5
OMA	MGAINRC
OrthoDB	EOG72RMXP
ChiTaRS	RNF112
GenomeRNAi	7732
NextBio	29940
PRO	PR:Q9ULX5
Proteomes	UP000005640
Bgee	Q9ULX5
CleanEx	HS_RNF112
ExpressionAtlas	Q9ULX5
Genevestigator	Q9ULX5
GO	GO:0005737 GO:0016021 GO:0005634 GO:0005525 GO:0003924 GO:0008270
Gene3D	3.30.40.10 3.40.50.300
InterPro	IPR030386 IPR015894 IPR027417 IPR018957 IPR001841 IPR013083
Pfam	PF02263 PF00097
SMART	SM00184
SUPFAM	SSF52540
PROSITE	PS51715 PS50089

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0044297	cell body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0019898	extrinsic component of membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	C	Seeded From UniProt	complete
enables	GO:0061630	ubiquitin protein ligase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	F	Seeded From UniProt	complete
enables	GO:0043621	protein self-association	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	F	Seeded From UniProt	complete
involved_in	GO:1990403	embryonic brain development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	P	Seeded From UniProt	complete
involved_in	GO:0051865	protein autoubiquitination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	P	Seeded From UniProt	complete
involved_in	GO:0036474	cell death in response to hydrogen peroxide	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	P	Seeded From UniProt	complete
involved_in	GO:0036473	cell death in response to oxidative stress	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	P	Seeded From UniProt	complete
involved_in	GO:0033194	response to hydroperoxide	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96DY5	P	Seeded From UniProt	complete
involved_in	GO:0007050	cell cycle arrest	PMID:28684796^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:28684796^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	PMID:8660987^[2]	ECO:0000303	author statement without traceable support used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:1990403	embryonic brain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
involved_in	GO:0071158	positive regulation of cell cycle arrest	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
enables	GO:0061630	ubiquitin protein ligase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	F	Seeded From UniProt	complete
involved_in	GO:0051865	protein autoubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
involved_in	GO:0045687	positive regulation of glial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
enables	GO:0043621	protein self-association	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	F	Seeded From UniProt	complete
involved_in	GO:0036474	cell death in response to hydrogen peroxide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
involved_in	GO:0036473	cell death in response to oxidative stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
involved_in	GO:0033194	response to hydroperoxide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	P	Seeded From UniProt	complete
part_of	GO:0019898	extrinsic component of membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96DY5 ensembl:ENSMUSP00000056464	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015894	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015894 InterPro:IPR030386	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018957	F	Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0628	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967 UniProtKB-SubCell:SL-0101	C	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003	C	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770	C	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0494	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0190	C	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0297	C	Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0259	C	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Lee, KH et al. (2017) Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway. Sci Rep 7 4787 PubMed GONUTS page
↑ Matsuda, Y et al. (1996) Chromosome mapping of human (ZNF179), mouse, and rat genes for brain finger protein (bfp), a member of the RING finger family. Genomics 33 325-7 PubMed GONUTS page

[PMID:28684796-1] 1.0 ^1.1 Lee, KH et al. (2017) Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway. Sci Rep 7 4787 PubMed GONUTS page

[PMID:8660987-2] Matsuda, Y et al. (1996) Chromosome mapping of human (ZNF179), mouse, and rat genes for brain finger protein (bfp), a member of the RING finger family. Genomics 33 325-7 PubMed GONUTS page

[1]

[2]

HUMAN:RN112

Contents

Annotations

Notes

References

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