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HUMAN:RAD54
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | RAD54L (synonyms: RAD54A) | |
| Protein Name(s) | DNA repair and recombination protein RAD54-like
RAD54 homolog hHR54 hRAD54 | |
| External Links | ||
| UniProt | Q92698 | |
| EMBL | X97795 AY623117 AL121602 BC121059 BC121060 | |
| CCDS | CCDS532.1 | |
| RefSeq | NP_001136020.1 NP_003570.2 | |
| UniGene | Hs.642042 | |
| ProteinModelPortal | Q92698 | |
| SMR | Q92698 | |
| BioGrid | 114018 | |
| DIP | DIP-48628N | |
| ELM | Q92698 | |
| IntAct | Q92698 | |
| STRING | 9606.ENSP00000361043 | |
| BindingDB | Q92698 | |
| ChEMBL | CHEMBL2146297 | |
| iPTMnet | Q92698 | |
| PhosphoSitePlus | Q92698 | |
| BioMuta | RAD54L | |
| DMDM | 51316508 | |
| EPD | Q92698 | |
| MaxQB | Q92698 | |
| PaxDb | Q92698 | |
| PeptideAtlas | Q92698 | |
| PRIDE | Q92698 | |
| Ensembl | ENST00000371975 ENST00000442598 | |
| GeneID | 8438 | |
| KEGG | hsa:8438 | |
| UCSC | uc001cpl.3 | |
| CTD | 8438 | |
| DisGeNET | 8438 | |
| EuPathDB | HostDB:ENSG00000085999.11 | |
| GeneCards | RAD54L | |
| HGNC | HGNC:9826 | |
| HPA | HPA028954 HPA051537 | |
| MalaCards | RAD54L | |
| MIM | 603615 | |
| neXtProt | NX_Q92698 | |
| OpenTargets | ENSG00000085999 | |
| PharmGKB | PA34181 | |
| eggNOG | KOG0390 COG0553 | |
| GeneTree | ENSGT00910000144164 | |
| HOGENOM | HOG000204521 | |
| HOVERGEN | HBG058654 | |
| InParanoid | Q92698 | |
| KO | K10875 | |
| OMA | NILRPHQ | |
| OrthoDB | EOG091G01Z3 | |
| PhylomeDB | Q92698 | |
| TreeFam | TF101224 | |
| ChiTaRS | RAD54L | |
| GeneWiki | DNA_repair_and_recombination_protein_RAD54-like | |
| GenomeRNAi | 8438 | |
| PRO | PR:Q92698 | |
| Proteomes | UP000005640 | |
| Bgee | ENSG00000085999 | |
| CleanEx | HS_RAD54L | |
| ExpressionAtlas | Q92698 | |
| Genevisible | Q92698 | |
| GO | GO:0005654 GO:0005634 GO:0043234 GO:0036310 GO:0005524 GO:0003677 GO:0004386 GO:0008340 GO:0006310 GO:0006281 GO:0000724 GO:0051321 GO:0042493 GO:0010212 | |
| CDD | cd00079 | |
| InterPro | IPR014001 IPR001650 IPR027417 IPR000330 | |
| Pfam | PF00271 PF00176 | |
| SMART | SM00487 SM00490 | |
| SUPFAM | SSF52540 | |
| PROSITE | PS51192 PS51194 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0036310 |
annealing helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000733 |
DNA strand renaturation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0036310 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051276 |
chromosome organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042493 |
response to drug |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010212 |
response to ionizing radiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008340 |
determination of adult lifespan |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006302 |
double-strand break repair |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000724 |
double-strand break repair via homologous recombination |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P70270 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051321 |
meiotic cell cycle |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004386 |
helicase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kovalenko, OV et al. (2006) RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51. Nucleic Acids Res. 34 5081-92 PubMed GONUTS page
- ↑ Yuan, J et al. (2012) The HARP-like domain-containing protein AH2/ZRANB3 binds to PCNA and participates in cellular response to replication stress. Mol. Cell 47 410-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Kanaar, R et al. (1996) Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation. Curr. Biol. 6 828-38 PubMed GONUTS page
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