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HUMAN:Q96AW5

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) QARS (ECO:0000313 with EMBL:AAH16634.2)
Protein Name(s) QARS protein (ECO:0000313 with EMBL:AAH16634.2)
External Links
UniProt Q96AW5
EMBL BC016634
UniGene Hs.79322
ProteinModelPortal Q96AW5
IntAct Q96AW5
PRIDE Q96AW5
HOVERGEN HBG000889
ChiTaRS QARS
GO GO:0005737
GO:0005524
GO:0004819
GO:0006425
Gene3D 1.10.1160.10
2.40.240.10
3.40.50.620
InterPro IPR001412
IPR004514
IPR007638
IPR007639
IPR000924
IPR020061
IPR020058
IPR020059
IPR020056
IPR011035
IPR014729
PANTHER PTHR10119
Pfam PF00749
PF03950
PF04558
PF04557
PRINTS PR00987
SUPFAM SSF50715
TIGRFAMs TIGR00440
PROSITE PS00178

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045727

positive regulation of translation

PMID:25790369[1]

ECO:0000315

P

Fig.6B QARS downregulation via siRNA knockout stops global protein synthesis

complete
CACAO 10792

involved_in

GO:0045727

positive regulation of translation

PMID:25790369[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000924
InterPro:IPR001412
InterPro:IPR004514
InterPro:IPR007638
InterPro:IPR007639
InterPro:IPR020059

F

Seeded From UniProt

complete

enables

GO:0004812

aminoacyl-tRNA ligase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000924
InterPro:IPR001412
InterPro:IPR007639
InterPro:IPR020058
InterPro:IPR020059

F

Seeded From UniProt

complete

enables

GO:0004819

glutamine-tRNA ligase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004514
InterPro:IPR007638

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000924
InterPro:IPR001412
InterPro:IPR004514
InterPro:IPR007638
InterPro:IPR007639
InterPro:IPR020058
InterPro:IPR020059

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004514
InterPro:IPR007638
InterPro:IPR007639
InterPro:IPR020059

C

Seeded From UniProt

complete

involved_in

GO:0006412

translation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011035

P

Seeded From UniProt

complete

involved_in

GO:0006418

tRNA aminoacylation for protein translation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001412
InterPro:IPR007639
InterPro:IPR020059

P

Seeded From UniProt

complete

involved_in

GO:0006425

glutaminyl-tRNA aminoacylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004514
InterPro:IPR007638

P

Seeded From UniProt

complete

involved_in

GO:0043039

tRNA aminoacylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000924
InterPro:IPR020058

P

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

involved_in

GO:0006412

translation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0648

P

Seeded From UniProt

complete

enables

GO:0004812

aminoacyl-tRNA ligase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0030

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Papageorgiou, A et al. (2015) A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation. PLoS ONE 10 e0116096 PubMed GONUTS page