HUMAN:Q53T26

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	PELI1 (ECO:0000313 with EMBL:AAY24274.1)
Protein Name(s)	Pellino (ECO:0000313 with EMBL:AAQ76816.1) Pellino homolog 1 (Drosophila), isoform CRA_a (ECO:0000313 with EMBL:EAW99948.1) Putative uncharacterized protein PELI1 (ECO:0000313 with EMBL:AAY24274.1) cDNA, FLJ92790, Homo sapiens pellino homolog 1 (Drosophila) (PELI1), mRNA (ECO:0000313 with EMBL:BAG35350.1)
External Links
UniProt	Q53T26
EMBL	AY364257 AC012368 AK312441 CH471053 CH471053
RefSeq	NP_065702.2
UniGene	Hs.7886
SMR	Q53T26
DNASU	57162
GeneID	57162
KEGG	hsa:57162
CTD	57162
PharmGKB	PA33172
HOVERGEN	HBG053559
KO	K11964
OMA	SGEQGYI
PhylomeDB	Q53T26
GenomeRNAi	57162
NextBio	63169
GO	GO:0005634 GO:0004842 GO:0032088 GO:0042130 GO:0030890 GO:0001819 GO:0043123 GO:0031398 GO:0034141 GO:0034145 GO:0070936 GO:0043331 GO:0032496 GO:0008063
InterPro	IPR006800
PANTHER	PTHR12098
Pfam	PF04710
PIRSF	PIRSF038886

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0070936	protein K48-linked ubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
enables	GO:0061630	ubiquitin protein ligase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	F		Seeded From UniProt	complete
involved_in	GO:0060546	negative regulation of necroptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0050871	positive regulation of B cell activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0050868	negative regulation of T cell activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0043331	response to dsRNA	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0042130	negative regulation of T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0032496	response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0032088	negative regulation of NF-kappaB transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0031398	positive regulation of protein ubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0030890	positive regulation of B cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	C		Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	F		Seeded From UniProt	complete
involved_in	GO:0001819	positive regulation of cytokine production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8C669 ensembl:ENSMUSP00000099018	P		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006800	P		Seeded From UniProt	complete
involved_in	GO:0008592	regulation of Toll signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006800	P		Seeded From UniProt	complete
enables	GO:0061630	ubiquitin protein ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006800	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0008063	Toll signaling pathway	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000668758	P		Seeded From UniProt	complete
enables	GO:0061630	ubiquitin protein ligase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000668758	F		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P		Seeded From UniProt	complete
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References

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