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HUMAN:PLAL2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) PLAGL2 (synonyms: KIAA0198)
Protein Name(s) Zinc finger protein PLAGL2

Pleiomorphic adenoma-like protein 2

External Links
UniProt Q9UPG8
EMBL AF006005
D83784
AK292450
AL121897
CH471077
CH471077
BC023655
CCDS CCDS13197.1
RefSeq NP_002648.1
XP_005260493.1
UniGene Hs.154104
ProteinModelPortal Q9UPG8
SMR Q9UPG8
BioGrid 111342
IntAct Q9UPG8
STRING 9606.ENSP00000246229
PhosphoSite Q9UPG8
DMDM 14548188
MaxQB Q9UPG8
PaxDb Q9UPG8
PRIDE Q9UPG8
DNASU 5326
Ensembl ENST00000246229
GeneID 5326
KEGG hsa:5326
UCSC uc002wxn.2
CTD 5326
GeneCards GC20M030780
HGNC HGNC:9047
HPA HPA005900
MIM 604866
neXtProt NX_Q9UPG8
PharmGKB PA33380
eggNOG COG5048
GeneTree ENSGT00390000013640
HOGENOM HOG000294191
HOVERGEN HBG053608
InParanoid Q9UPG8
OMA TWPFAIS
OrthoDB EOG71K62Q
PhylomeDB Q9UPG8
TreeFam TF332024
GeneWiki PLAGL2
GenomeRNAi 5326
NextBio 20618
PRO PR:Q9UPG8
Proteomes UP000005640
Bgee Q9UPG8
CleanEx HS_PLAGL2
Genevestigator Q9UPG8
GO GO:0005634
GO:0046872
GO:0001077
GO:0043565
GO:0003700
GO:0034378
GO:0006629
GO:2001244
GO:0009791
Gene3D 3.30.160.60
InterPro IPR027775
IPR007087
IPR015880
IPR013087
PANTHER PTHR10032
SMART SM00355
PROSITE PS00028
PS50157

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000113

ECO:0005556

multiple sequence alignment evidence used in manual assertion

UniProtKB:E9Q3T6
UniProtKB:O14978
UniProtKB:O95125
UniProtKB:O95863
UniProtKB:P10071
UniProtKB:P10754
UniProtKB:P17028
UniProtKB:P28698
UniProtKB:P36508
UniProtKB:P41183
UniProtKB:P47806
UniProtKB:P52738
UniProtKB:Q02085
UniProtKB:Q05516
UniProtKB:Q08376
UniProtKB:Q0VDQ9
UniProtKB:Q16600
UniProtKB:Q61967
UniProtKB:Q6DJT9
UniProtKB:Q6NUN9
UniProtKB:Q86UQ0
UniProtKB:Q8CIV7
UniProtKB:Q8K0L9
UniProtKB:Q8K3J5
UniProtKB:Q8NI51
UniProtKB:Q91ZD1
UniProtKB:Q96RE9
UniProtKB:Q99684
UniProtKB:Q9BU19
UniProtKB:Q9ESP5
UniProtKB:Q9GZX5
UniProtKB:Q9H116
UniProtKB:Q9NQX1
UniProtKB:Q9NZL3
UniProtKB:Q9QY31
UniProtKB:Q9UM63
UniProtKB:Q9UPG8
UniProtKB:Q9UQR1
UniProtKB:Q9WTJ2
UniProtKB:Q9Y2X9
UniProtKB:Q9Y473
UniProtKB:Q9Y5A6

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:15361364[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:15361364[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:2001244

positive regulation of intrinsic apoptotic signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925T4
ensembl:ENSMUSP00000105419

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925T4
ensembl:ENSMUSP00000105419

P

Seeded From UniProt

complete

involved_in

GO:0034378

chylomicron assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925T4
ensembl:ENSMUSP00000105419

P

Seeded From UniProt

complete

involved_in

GO:0009791

post-embryonic development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925T4
ensembl:ENSMUSP00000105419

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925T4
ensembl:ENSMUSP00000105419

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925T4
ensembl:ENSMUSP00000105419

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013087

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:9722527[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
  2. 2.0 2.1 Yang, MC et al. (2005) Pleiomorphic adenoma gene-like-2, a zinc finger protein, transactivates the surfactant protein-C promoter. Am. J. Respir. Cell Mol. Biol. 32 35-43 PubMed GONUTS page
  3. Kas, K et al. (1998) Transcriptional activation capacity of the novel PLAG family of zinc finger proteins. J. Biol. Chem. 273 23026-32 PubMed GONUTS page