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HUMAN:PEPA3
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | PGA3 | |
| Protein Name(s) | Pepsin A-3
Pepsinogen-3 | |
| External Links | ||
| UniProt | P0DJD8 | |
| EMBL | AK312941 AK125628 AP000437 BC171815 | |
| CCDS | CCDS31574.1 | |
| PIR | A00980 A30142 A92058 B30142 | |
| RefSeq | NP_001073275.1 XP_005276461.1 | |
| UniGene | Hs.601055 Hs.661883 | |
| ProteinModelPortal | P0DJD8 | |
| SMR | P0DJD8 | |
| PhosphoSite | P0DJD8 | |
| DMDM | 378521956 | |
| PRIDE | P0DJD8 | |
| Ensembl | ENST00000325558 | |
| GeneID | 101929842 643834 | |
| KEGG | hsa:101929842 hsa:643834 | |
| UCSC | uc001nqx.3 | |
| CTD | 643834 | |
| GeneCards | GC11P060970 | |
| HGNC | HGNC:8885 | |
| HPA | CAB026358 HPA046875 | |
| MIM | 169700 169710 | |
| neXtProt | NX_P0DJD8 | |
| eggNOG | NOG248684 | |
| GeneTree | ENSGT00760000118929 | |
| HOGENOM | HOG000197681 | |
| HOVERGEN | HBG000482 | |
| InParanoid | P0DJD8 | |
| KO | K06002 | |
| OMA | XNDESGS | |
| OrthoDB | EOG7HQN88 | |
| PhylomeDB | P0DJD8 | |
| TreeFam | TF314990 | |
| ChiTaRS | PGA3 | |
| NextBio | 115445 | |
| PRO | PR:P0DJD8 | |
| Proteomes | UP000005640 | |
| Bgee | P0DJD8 | |
| CleanEx | HS_PGA3 | |
| ExpressionAtlas | P0DJD8 | |
| GO | GO:0070062 GO:0004190 GO:0007586 | |
| Gene3D | 2.40.70.10 | |
| InterPro | IPR001461 IPR001969 IPR012848 IPR021109 | |
| PANTHER | PTHR13683 | |
| Pfam | PF07966 PF00026 | |
| PRINTS | PR00792 | |
| SUPFAM | SSF50630 | |
| PROSITE | PS00141 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004194 |
pepsin A activity |
ECO:0000314 |
F |
Causes extraesophageal reflux and may be involved in middle ear inflammatory process |
complete | |||||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030163 |
protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000201569 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000190503 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000196689 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0097486 |
multivesicular body lumen |
Reactome:R-HSA-5685902 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0044267 |
cellular protein metabolic process |
Reactome:R-HSA-392499 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007586 |
digestion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ O'Reilly, RC et al. (2015) The role of gastric pepsin in the inflammatory cascade of pediatric otitis media. JAMA Otolaryngol Head Neck Surg 141 350-7 PubMed GONUTS page
- ↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
