GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:PEA15
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | PEA15 | |
| Protein Name(s) | Astrocytic phosphoprotein PEA-15
15 kDa phosphoprotein enriched in astrocytes Phosphoprotein enriched in diabetes PED | |
| External Links | ||
| UniProt | Q15121 | |
| EMBL | X86809 Y13736 AF153274 AF153273 AK095879 AL121987 AL139011 CH471121 BC002426 BC022554 BT007252 | |
| CCDS | CCDS1199.1 CCDS72954.1 | |
| PIR | S55384 | |
| RefSeq | NP_001284505.1 NP_001284506.1 NP_001284507.1 NP_003759.1 XP_005245621.1 XP_006711662.1 | |
| UniGene | Hs.517216 | |
| PDB | 4IZ5 4IZA | |
| PDBsum | 4IZ5 4IZA | |
| ProteinModelPortal | Q15121 | |
| SMR | Q15121 | |
| BioGrid | 114230 | |
| IntAct | Q15121 | |
| MINT | MINT-141556 | |
| STRING | 9606.ENSP00000353660 | |
| PhosphoSite | Q15121 | |
| DMDM | 32470612 | |
| MaxQB | Q15121 | |
| PaxDb | Q15121 | |
| PRIDE | Q15121 | |
| DNASU | 8682 | |
| Ensembl | ENST00000360472 ENST00000368076 | |
| GeneID | 8682 | |
| KEGG | hsa:8682 | |
| UCSC | uc001fvk.3 uc001fvl.3 | |
| CTD | 8682 | |
| GeneCards | GC01P160175 | |
| HGNC | HGNC:8822 | |
| HPA | HPA028356 | |
| MIM | 603434 | |
| neXtProt | NX_Q15121 | |
| PharmGKB | PA33166 | |
| eggNOG | NOG314638 | |
| GeneTree | ENSGT00390000000230 | |
| HOGENOM | HOG000049048 | |
| HOVERGEN | HBG053557 | |
| InParanoid | Q15121 | |
| OMA | CKEDIPE | |
| OrthoDB | EOG7D2FGM | |
| PhylomeDB | Q15121 | |
| TreeFam | TF332405 | |
| SignaLink | Q15121 | |
| ChiTaRS | PEA15 | |
| GeneWiki | PEA15 | |
| GenomeRNAi | 8682 | |
| NextBio | 32565 | |
| PMAP-CutDB | Q15121 | |
| PRO | PR:Q15121 | |
| Proteomes | UP000005640 | |
| Bgee | Q15121 | |
| CleanEx | HS_PEA15 | |
| ExpressionAtlas | Q15121 | |
| Genevestigator | Q15121 | |
| GO | GO:0005737 GO:0005875 GO:0006915 GO:0008643 GO:0000077 GO:1902042 GO:0046325 GO:0006810 | |
| Gene3D | 1.10.533.10 | |
| InterPro | IPR011029 IPR001875 IPR029546 | |
| PANTHER | PTHR15094:SF0 | |
| Pfam | PF01335 | |
| SMART | SM00031 | |
| SUPFAM | SSF47986 | |
| PROSITE | PS50168 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:1902042 |
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046325 |
negative regulation of glucose import |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005875 |
microtubule associated complex |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043278 |
response to morphine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5U318 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1902043 |
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q62048 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1902042 |
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q62048 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000077 |
DNA damage checkpoint |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042981 |
regulation of apoptotic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-5675206 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000187 |
activation of MAPK activity |
Reactome:R-HSA-112409 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000165 |
MAPK cascade |
Reactome:R-HSA-5673001 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008643 |
carbohydrate transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Condorelli, G et al. (1999) PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis. Oncogene 18 4409-15 PubMed GONUTS page
- ↑ Condorelli, G et al. (1998) PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus. EMBO J. 17 3858-66 PubMed GONUTS page
- ↑ Estellés, A et al. (1996) The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human. J. Biol. Chem. 271 14800-6 PubMed GONUTS page
c
n
p
