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HUMAN:MTUS2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) MTUS2 (synonyms: CAZIP, KIAA0774, TIP150)
Protein Name(s) Microtubule-associated tumor suppressor candidate 2

Cardiac zipper protein Microtubule plus-end tracking protein TIP150 Tracking protein of 150 kDa

External Links
UniProt Q5JR59
EMBL AB018317
AK293970
AL596114
AL160255
AL596092
AL607144
AL596114
AL607144
AL596092
AL160255
AL596114
AL607144
AL607144
AL160255
AL596092
AL596114
AL607144
AL596114
AL160255
AL596092
AL596114
AL607144
BC032481
BC119654
BC119655
BC129985
BC150245
CCDS CCDS41874.1
RefSeq NP_001028774.2
NP_056048.1
UniGene Hs.22287
ProteinModelPortal Q5JR59
BioGrid 116880
IntAct Q5JR59
MINT MINT-1457050
STRING 9606.ENSP00000255289
PhosphoSite Q5JR59
DMDM 259016371
MaxQB Q5JR59
PaxDb Q5JR59
PRIDE Q5JR59
DNASU 23281
Ensembl ENST00000380808
ENST00000542829
GeneID 23281
KEGG hsa:23281
UCSC uc001usm.4
uc010aau.3
CTD 23281
GeneCards GC13P029599
H-InvDB HIX0020942
HGNC HGNC:20595
HPA HPA031474
HPA031475
neXtProt NX_Q5JR59
PharmGKB PA165505194
eggNOG NOG119660
GeneTree ENSGT00390000006245
InParanoid Q5JR59
PhylomeDB Q5JR59
ChiTaRS MTUS2
GenomeRNAi 23281
NextBio 45074
PRO PR:Q5JR59
Proteomes UP000005640
Bgee Q5JR59
CleanEx HS_KIAA0774
ExpressionAtlas Q5JR59
Genevestigator Q5JR59
GO GO:0005737
GO:0005874
GO:0008017
GO:0042803

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005634

nucleus

PMID:19806667[1]

ECO:0000314

C

Fig. 7 Through immunoflourescence, the protein was tagged by Myc with a flourescent tag. This showed evidence of the protein being expressed in the subnuclear structures in the nucleus.

complete
CACAO 6783

part_of

GO:0005634

nucleus

PMID:19806667[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:19543227[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q5JR59

F

Seeded From UniProt

complete

enables

GO:0008017

microtubule binding

PMID:19543227[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

colocalizes_with

GO:0005881

cytoplasmic microtubule

PMID:19543227[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0005813

centrosome

PMID:19543227[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0015630

microtubule cytoskeleton

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001271408
UniProtKB:Q5JR59
UniProtKB:Q9ULD2

C

Seeded From UniProt

complete

enables

GO:0008017

microtubule binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001271408
UniProtKB:Q5JR59

F

Seeded From UniProt

complete

colocalizes_with

GO:0005737

cytoplasm

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2142572
PANTHER:PTN001271408

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001271408
UniProtKB:Q5JR59

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

part_of

GO:0005874

microtubule

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0493

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Du Puy, L et al. (2009) CAZIP, a novel protein expressed in the developing heart and nervous system. Dev. Dyn. 238 2903-11 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Jiang, K et al. (2009) TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep. 10 857-65 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page