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HUMAN:MEIS1
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | MEIS1 | |
Protein Name(s) | Homeobox protein Meis1 | |
External Links | ||
UniProt | O00470 | |
EMBL | U85707 CR612956 AC007392 AC092669 AC093641 BC043503 | |
CCDS | CCDS46309.1 | |
RefSeq | NP_002389.1 | |
UniGene | Hs.526754 Hs.603755 | |
ProteinModelPortal | O00470 | |
SMR | O00470 | |
BioGrid | 110375 | |
IntAct | O00470 | |
STRING | 9606.ENSP00000272369 | |
PhosphoSite | O00470 | |
MaxQB | O00470 | |
PaxDb | O00470 | |
PRIDE | O00470 | |
Ensembl | ENST00000272369 ENST00000398506 | |
GeneID | 4211 | |
KEGG | hsa:4211 | |
UCSC | uc002sdt.3 | |
CTD | 4211 | |
GeneCards | GC02P066660 | |
HGNC | HGNC:7000 | |
HPA | CAB011521 HPA056000 | |
MIM | 601739 612853 | |
neXtProt | NX_O00470 | |
PharmGKB | PA30740 | |
eggNOG | NOG302919 | |
GeneTree | ENSGT00550000074260 | |
HOGENOM | HOG000253923 | |
HOVERGEN | HBG055193 | |
InParanoid | O00470 | |
KO | K15613 | |
PhylomeDB | O00470 | |
TreeFam | TF318093 | |
SignaLink | O00470 | |
ChiTaRS | MEIS1 | |
GeneWiki | MEIS1 | |
GenomeRNAi | 4211 | |
NextBio | 16590 | |
PRO | PR:O00470 | |
Proteomes | UP000005640 | |
Bgee | O00470 | |
CleanEx | HS_MEIS1 | |
ExpressionAtlas | O00470 | |
Genevestigator | O00470 | |
GO | GO:0005634 GO:0005667 GO:0003682 GO:0000978 GO:0001077 GO:0003705 GO:0001525 GO:0060216 GO:0002089 GO:0035855 GO:0045638 GO:0045665 | |
Gene3D | 1.10.10.60 | |
InterPro | IPR001356 IPR008422 IPR009057 | |
Pfam | PF05920 | |
SMART | SM00389 | |
SUPFAM | SSF46689 | |
PROSITE | PS50071 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0001525 |
angiogenesis |
ECO:0000314 |
P |
Figure 1: epigenetic signatures in vitro |
complete | |||||
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045638 |
negative regulation of myeloid cell differentiation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060044 |
negative regulation of cardiac muscle cell proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:B1WC31 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060216 |
definitive hemopoiesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048514 |
blood vessel morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0046982 |
protein heterodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045665 |
negative regulation of neuron differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045638 |
negative regulation of myeloid cell differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035855 |
megakaryocyte development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030097 |
hemopoiesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007626 |
locomotory behavior |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003682 |
chromatin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002089 |
lens morphogenesis in camera-type eye |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001525 |
angiogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q60954 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Spieler, D et al. (2014) Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. Genome Res. 24 592-603 PubMed GONUTS page
- ↑ Jolma, A et al. (2015) DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527 384-8 PubMed GONUTS page
- ↑ 3.0 3.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
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