HUMAN:IMDH2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	IMPDH2 (ECO:0000255 with HAMAP-Rule:MF_03156) (synonyms: IMPD2)
Protein Name(s)	Inosine-5'-monophosphate dehydrogenase 2 (ECO:0000255 with HAMAP-Rule:MF_03156) IMP dehydrogenase 2 (ECO:0000255 with HAMAP-Rule:MF_03156) IMPD 2 (ECO:0000255 with HAMAP-Rule:MF_03156) IMPDH 2 (ECO:0000255 with HAMAP-Rule:MF_03156) IMPDH-II
External Links
UniProt	P12268
EMBL	J04208 L33842 L39210 BC006124 BC012840 BC015567 L08114
CCDS	CCDS2786.1
PIR	I52303
RefSeq	NP_000875.2
PDB	1B3O 1NF7 1NFB 6I0M 6I0O
PDBsum	1B3O 1NF7 1NFB 6I0M 6I0O
SMR	P12268
BioGrid	109828
IntAct	P12268
MINT	P12268
STRING	9606.ENSP00000321584
BindingDB	P12268
ChEMBL	CHEMBL2002
DrugBank	DB03948 DB04566 DB01033 DB00688 DB01024 DB00157 DB00811 DB03070 DB06103
DrugCentral	P12268
GuidetoPHARMACOLOGY	2625
iPTMnet	P12268
PhosphoSitePlus	P12268
SwissPalm	P12268
BioMuta	IMPDH2
DMDM	124419
REPRODUCTION-2DPAGE	IPI00291510 P12268
UCD-2DPAGE	P12268
EPD	P12268
jPOST	P12268
MassIVE	P12268
MaxQB	P12268
PaxDb	P12268
PeptideAtlas	P12268
PRIDE	P12268
ProteomicsDB	52839
TopDownProteomics	P12268
DNASU	3615
Ensembl	ENST00000326739
GeneID	3615
KEGG	hsa:3615
UCSC	uc003cvt.4
CTD	3615
DisGeNET	3615
GeneCards	IMPDH2
HGNC	HGNC:6053
HPA	CAB020717 HPA001400
MalaCards	IMPDH2
MIM	146691 617995
neXtProt	NX_P12268
OpenTargets	ENSG00000178035
PharmGKB	PA29863
eggNOG	KOG2550 COG0516 COG0517
GeneTree	ENSGT00940000157726
HOGENOM	HOG000165752
KO	K00088
OMA	HDYHMTL
OrthoDB	1213216at2759
PhylomeDB	P12268
TreeFam	TF300378
BioCyc	MetaCyc:HS11242-MONOMER
BRENDA	1.1.1.205
Reactome	R-HSA-6798695 R-HSA-73817
SABIO-RK	P12268
UniPathway	UPA00601
ChiTaRS	IMPDH2
EvolutionaryTrace	P12268
GeneWiki	IMPDH2
GenomeRNAi	3615
Pharos	P12268
PRO	PR:P12268
Proteomes	UP000005640
Bgee	ENSG00000178035
ExpressionAtlas	P12268
Genevisible	P12268
GO	GO:0005737 GO:0005829 GO:0070062 GO:0005576 GO:1904813 GO:0016020 GO:0005634 GO:0005778 GO:0034774 GO:0003677 GO:0003938 GO:0046872 GO:0000166 GO:0003723 GO:0071353 GO:0007623 GO:0006177 GO:0006183 GO:0046651 GO:0043312 GO:0051289 GO:0009168 GO:0060041
CDD	cd00381
Gene3D	3.20.20.70
HAMAP	MF_01964
InterPro	IPR013785 IPR000644 IPR005990 IPR015875 IPR001093
Pfam	PF00571 PF00478
PIRSF	PIRSF000130
SMART	SM00116
TIGRFAMs	TIGR01302
PROSITE	PS51371 PS00487

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes
involved_in	GO:0007623	circadian rhythm	PMID:28985504^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt
part_of	GO:0016020	membrane	PMID:19946888^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0070062	extracellular exosome	PMID:20458337^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0070062	extracellular exosome	PMID:20458337^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000639)	Seeded From UniProt
part_of	GO:0005778	peroxisomal membrane	PMID:21525035^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0005737	cytoplasm	PMID:14766016^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0005634	nucleus	PMID:14766016^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt
enables	GO:0000166	nucleotide binding	PMID:14766016^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt
involved_in	GO:0006183	GTP biosynthetic process	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000226903 PomBase:SPBC2F12.14c	P		Seeded From UniProt
part_of	GO:0005737	cytoplasm	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000226902 SGD:S000001259 SGD:S000004424 SGD:S000004520 UniProtKB:P12268 UniProtKB:P20839	C		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10421 MGI:MGI:109367 MGI:MGI:96567 PANTHER:PTN000226903 PomBase:SPBC2F12.14c RGD:735092 UniProtKB:P9WKI5 UniProtKB:P9WKI7	F		Seeded From UniProt
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt
involved_in	GO:0060041	retina development in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	P		Seeded From UniProt
involved_in	GO:0051289	protein homotetramerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	P		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	P		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	F		Seeded From UniProt
involved_in	GO:0071353	cellular response to interleukin-4	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	P		Seeded From UniProt
involved_in	GO:0046651	lymphocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	P		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	P		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	F		Seeded From UniProt
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001093 InterPro:IPR013785	F		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005990	F		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005990	P		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015875	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001093 InterPro:IPR005990 InterPro:IPR015875	P		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.205	F		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	F		Seeded From UniProt
involved_in	GO:0006177	GMP biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	P		Seeded From UniProt
part_of	GO:0005634	nucleus	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	C		Seeded From UniProt
enables	GO:0000166	nucleotide binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	F		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	F		Seeded From UniProt
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	C		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	PMID:1969416^[7]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt
part_of	GO:1904813	ficolin-1-rich granule lumen	Reactome:R-HSA-6800434	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
involved_in	GO:0043312	neutrophil degranulation	Reactome:R-HSA-6798695	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt
part_of	GO:0034774	secretory granule lumen	Reactome:R-HSA-6798748	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
involved_in	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	Reactome:R-HSA-73817	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt
part_of	GO:0005829	cytosol	Reactome:R-HSA-73794	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
part_of	GO:0005576	extracellular region	Reactome:R-HSA-6800434 Reactome:R-HSA-6798748	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0658	P		Seeded From UniProt
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt
involved_in	GO:0006177	GMP biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0332	P		Seeded From UniProt
enables	GO:0005515	protein binding	PMID:28985504^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O15516	F		Seeded From UniProt
involved_in	GO:0007623	circadian rhythm	PMID:28985504^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt
part_of	GO:0016020	membrane	PMID:19946888^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0070062	extracellular exosome	PMID:20458337^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0070062	extracellular exosome	PMID:20458337^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000639)	Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	PMID:1969416^[7]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt
part_of	GO:0005778	peroxisomal membrane	PMID:21525035^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0005737	cytoplasm	PMID:14766016^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt
part_of	GO:0005634	nucleus	PMID:14766016^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt
enables	GO:0000166	nucleotide binding	PMID:14766016^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt
involved_in	GO:0006183	GTP biosynthetic process	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000226903 PomBase:SPBC2F12.14c	P		Seeded From UniProt
part_of	GO:0005737	cytoplasm	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000226902 SGD:S000001259 SGD:S000004424 SGD:S000004520 UniProtKB:P12268 UniProtKB:P20839	C		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10421 MGI:MGI:109367 MGI:MGI:96567 PANTHER:PTN000226903 PomBase:SPBC2F12.14c RGD:735092 UniProtKB:P9WKI5 UniProtKB:P9WKI7	F		Seeded From UniProt
part_of	GO:1904813	ficolin-1-rich granule lumen	Reactome:R-HSA-6800434	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
involved_in	GO:0043312	neutrophil degranulation	Reactome:R-HSA-6798695	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt
part_of	GO:0034774	secretory granule lumen	Reactome:R-HSA-6798748	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
involved_in	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	Reactome:R-HSA-73817	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt
part_of	GO:0005829	cytosol	Reactome:R-HSA-73794	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
part_of	GO:0005576	extracellular region	Reactome:R-HSA-6800434 Reactome:R-HSA-6798748	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
part_of	GO:0005576	extracellular region	Reactome:R-HSA-6798748	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt
enables	GO:0005515	protein binding	PMID:25416956^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9BU20	F		Seeded From UniProt
enables	GO:0005515	protein binding	PMID:25416956^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q96GX9	F		Seeded From UniProt
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt
involved_in	GO:0060041	retina development in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	P		Seeded From UniProt
involved_in	GO:0051289	protein homotetramerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	P		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	P		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9PU28 ensembl:ENSRNOP00000040635	F		Seeded From UniProt
involved_in	GO:0071353	cellular response to interleukin-4	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	P		Seeded From UniProt
involved_in	GO:0046651	lymphocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	P		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	P		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P24547 ensembl:ENSMUSP00000079888	F		Seeded From UniProt
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001093 InterPro:IPR013785	F		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005990	F		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005990	P		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015875	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001093 InterPro:IPR005990 InterPro:IPR015875	P		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.205	F		Seeded From UniProt
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0658	P		Seeded From UniProt
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt
involved_in	GO:0006177	GMP biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0332	P		Seeded From UniProt
part_of	GO:0005737	cytoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0086	C		Seeded From UniProt
part_of	GO:0005634	nucleus	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0191	C		Seeded From UniProt
enables	GO:0046872	metal ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	F		Seeded From UniProt
involved_in	GO:0006177	GMP biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	P		Seeded From UniProt
part_of	GO:0005634	nucleus	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	C		Seeded From UniProt
enables	GO:0000166	nucleotide binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	F		Seeded From UniProt
enables	GO:0003938	IMP dehydrogenase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	F		Seeded From UniProt
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000336911	C		Seeded From UniProt
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Lin, R et al. (2017) CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis. Mol. Cell 68 198-209.e6 PubMed GONUTS page
↑ ^2.0 ^2.1 Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page
↑ ^4.0 ^4.1 Bharti, P et al. (2011) PEX14 is required for microtubule-based peroxisome motility in human cells. J. Cell. Sci. 124 1759-68 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 McLean, JE et al. (2004) Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo. Biochem. J. 379 243-51 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^7.0 ^7.1 Natsumeda, Y et al. (1990) Two distinct cDNAs for human IMP dehydrogenase. J. Biol. Chem. 265 5292-5 PubMed GONUTS page
↑ ^8.0 ^8.1 Rolland, T et al. (2014) A proteome-scale map of the human interactome network. Cell 159 1212-26 PubMed GONUTS page

[PMID:28985504-1] 1.0 ^1.1 ^1.2 Lin, R et al. (2017) CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis. Mol. Cell 68 198-209.e6 PubMed GONUTS page

[PMID:19946888-2] 2.0 ^2.1 Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page

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HUMAN:IMDH2

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