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HUMAN:HYPK

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) HYPK (synonyms: C15orf63)
Protein Name(s) Huntingtin-interacting protein K

Huntingtin yeast partner K

External Links
UniProt Q9NX55
EMBL AK000438
AK022435
AC018512
BC019262
AF161485
AF049613
CCDS CCDS10104.1
RefSeq NP_001186814.1
NP_057484.3
UniGene Hs.730672
DisProt DP00546
ProteinModelPortal Q9NX55
SMR Q9NX55
BioGrid 117304
IntAct Q9NX55
MINT MINT-1374304
STRING 9606.ENSP00000384474
PhosphoSite Q9NX55
DMDM 325511335
MaxQB Q9NX55
PaxDb Q9NX55
PRIDE Q9NX55
Ensembl ENST00000406925
ENST00000442995
GeneID 25764
KEGG hsa:25764
UCSC uc001ztb.3
CTD 25764
GeneCards GC15P044095
HGNC HGNC:18418
HPA HPA055252
MIM 612784
neXtProt NX_Q9NX55
PharmGKB PA165478509
eggNOG NOG312666
GeneTree ENSGT00390000008502
HOGENOM HOG000189569
HOVERGEN HBG060491
InParanoid Q9NX55
OrthoDB EOG7TBC4C
PhylomeDB Q9NX55
TreeFam TF325606
GenomeRNAi 25764
NextBio 46884
PRO PR:Q9NX55
Proteomes UP000005640
Bgee Q9NX55
ExpressionAtlas Q9NX55
Genevestigator Q9NX55
GO GO:0005737
GO:0005634

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:17947297[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

PMID:17947297[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0050821

protein stabilization

PMID:17947297[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:17947297[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:17947297[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0047485

protein N-terminus binding

PMID:17947297[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P42858

F

Seeded From UniProt

complete

part_of

GO:0015630

microtubule cytoskeleton

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CR41
ensembl:ENSMUSP00000106242

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Raychaudhuri, S et al. (2008) HYPK, a Huntingtin interacting protein, reduces aggregates and apoptosis induced by N-terminal Huntingtin with 40 glutamines in Neuro2a cells and exhibits chaperone-like activity. Hum. Mol. Genet. 17 240-55 PubMed GONUTS page