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HUMAN:DUPD1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | DUPD1 (synonyms: DUSP27) | |
| Protein Name(s) | Dual specificity phosphatase DUPD1
Dual specificity phosphatase 27 | |
| External Links | ||
| UniProt | Q68J44 | |
| EMBL | AY686755 BC137321 BC137322 | |
| CCDS | CCDS31223.1 | |
| RefSeq | NP_001003892.1 XP_005269819.1 | |
| UniGene | Hs.535090 | |
| PDB | 2Y96 | |
| PDBsum | 2Y96 | |
| ProteinModelPortal | Q68J44 | |
| SMR | Q68J44 | |
| STRING | 9606.ENSP00000340609 | |
| DEPOD | Q68J44 | |
| PhosphoSite | Q68J44 | |
| DMDM | 74748317 | |
| PaxDb | Q68J44 | |
| PRIDE | Q68J44 | |
| DNASU | 338599 | |
| Ensembl | ENST00000338487 | |
| GeneID | 338599 | |
| KEGG | hsa:338599 | |
| UCSC | uc001jwq.1 | |
| CTD | 338599 | |
| GeneCards | GC10M076797 | |
| HGNC | HGNC:23481 | |
| HPA | HPA042964 | |
| neXtProt | NX_Q68J44 | |
| PharmGKB | PA134959776 | |
| eggNOG | COG2453 | |
| GeneTree | ENSGT00760000118853 | |
| HOGENOM | HOG000233767 | |
| HOVERGEN | HBG001524 | |
| InParanoid | Q68J44 | |
| KO | K14165 | |
| OMA | RRAECAI | |
| OrthoDB | EOG7CZK7N | |
| PhylomeDB | Q68J44 | |
| TreeFam | TF105128 | |
| GenomeRNAi | 338599 | |
| NextBio | 97059 | |
| PRO | PR:Q68J44 | |
| Proteomes | UP000005640 | |
| Bgee | Q68J44 | |
| CleanEx | HS_DUPD1 HS_DUSP27 | |
| Genevestigator | Q68J44 | |
| GO | GO:0005737 GO:0004725 GO:0008138 GO:0006470 | |
| Gene3D | 3.90.190.10 | |
| InterPro | IPR020417 IPR020405 IPR000340 IPR020422 IPR024950 IPR029021 IPR000387 IPR016130 | |
| PANTHER | PTHR10159 | |
| Pfam | PF00782 | |
| PRINTS | PR01908 PR01909 | |
| SMART | SM00195 | |
| SUPFAM | SSF52799 | |
| PROSITE | PS00383 PS50056 PS50054 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006470 |
protein dephosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004725 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004725 |
P |
Seeded From UniProt |
complete | ||
| GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
ECO:0000314 |
F |
Figures 4B & 4D. |
complete | |||||
|
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006470 |
protein dephosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000340 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016791 |
phosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lountos, GT et al. (2011) Structure of human dual-specificity phosphatase 27 at 2.38 Å resolution. Acta Crystallogr. D Biol. Crystallogr. 67 471-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Friedberg, I et al. (2007) Identification and characterization of DUSP27, a novel dual-specific protein phosphatase. FEBS Lett. 581 2527-33 PubMed GONUTS page
p
- GO:0035335 ! peptidyl-tyrosine dephosphorylation
- GO:0016791 ! phosphatase activity
- GO:0004721 ! phosphoprotein phosphatase activity
- Primates
- GO:0032991 ! protein-containing complex
- GO:0006470 ! protein dephosphorylation
- GO:0042803 ! protein homodimerization activity
- GO:0008138 ! protein tyrosine/serine/threonine phosphatase activity
- GO:0004725 ! protein tyrosine phosphatase activity
