GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:DLX3
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | DLX3 | |
| Protein Name(s) | Homeobox protein DLX-3 | |
| External Links | ||
| UniProt | O60479 | |
| EMBL | AF028233 AF452638 AK075167 CH471109 BC012361 BC028970 | |
| CCDS | CCDS11556.1 | |
| RefSeq | NP_005211.1 | |
| UniGene | Hs.134194 | |
| ProteinModelPortal | O60479 | |
| SMR | O60479 | |
| BioGrid | 108091 | |
| IntAct | O60479 | |
| STRING | 9606.ENSP00000172196 | |
| PhosphoSite | O60479 | |
| MaxQB | O60479 | |
| PaxDb | O60479 | |
| PRIDE | O60479 | |
| DNASU | 1747 | |
| Ensembl | ENST00000434704 | |
| GeneID | 1747 | |
| KEGG | hsa:1747 | |
| UCSC | uc002ipy.3 | |
| CTD | 1747 | |
| GeneCards | GC17M048067 | |
| HGNC | HGNC:2916 | |
| HPA | HPA031164 | |
| MIM | 104510 190320 600525 | |
| neXtProt | NX_O60479 | |
| Orphanet | 100034 3352 | |
| PharmGKB | PA27371 | |
| eggNOG | NOG299102 | |
| GeneTree | ENSGT00770000120486 | |
| HOGENOM | HOG000231940 | |
| HOVERGEN | HBG005493 | |
| InParanoid | O60479 | |
| KO | K09315 | |
| OMA | SWYHTQN | |
| OrthoDB | EOG70W3F8 | |
| PhylomeDB | O60479 | |
| TreeFam | TF350606 | |
| GeneWiki | DLX3 DLX3_(gene) | |
| GenomeRNAi | 1747 | |
| NextBio | 7087 | |
| PRO | PR:O60479 | |
| Proteomes | UP000005640 | |
| Bgee | O60479 | |
| CleanEx | HS_DLX3 | |
| ExpressionAtlas | O60479 | |
| Genevestigator | O60479 | |
| GO | GO:0005634 GO:0003682 GO:0001077 GO:0043565 GO:0003700 GO:0001568 GO:0071895 GO:0042475 GO:0001890 | |
| Gene3D | 1.10.10.60 | |
| InterPro | IPR022135 IPR017970 IPR001356 IPR020479 IPR009057 IPR000047 | |
| Pfam | PF12413 PF00046 | |
| PRINTS | PR00024 PR00031 | |
| SMART | SM00389 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS00027 PS50071 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101926 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030855 |
epithelial cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:94903 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:94903 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101926 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000157 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1919200 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101926 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0001228 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071895 |
odontoblast differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042475 |
odontogenesis of dentin-containing tooth |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003682 |
chromatin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001890 |
placenta development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001568 |
blood vessel development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q64205 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000047 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Jolma, A et al. (2015) DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527 384-8 PubMed GONUTS page
- ↑ 2.0 2.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Price, JA et al. (1998) Identification of a mutation in DLX3 associated with tricho-dento-osseous (TDO) syndrome. Hum. Mol. Genet. 7 563-9 PubMed GONUTS page
d
p
r
