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HUMAN:DIXC1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) DIXDC1 (synonyms: CCD1, KIAA1735)
Protein Name(s) Dixin

Coiled-coil protein DIX1 Coiled-coil-DIX1 DIX domain-containing protein 1

External Links
UniProt Q155Q3
EMBL DQ642016
AB051522
AP000907
CH471065
BC033034
BC035509
BC041626
BC048294
BC064479
BC128600
AK055899
CCDS CCDS60957.1
CCDS73381.1
CCDS73382.1
RefSeq NP_001033043.1
NP_001265471.1
NP_219493.1
UniGene Hs.655626
PDB 3PZ7
PDBsum 3PZ7
ProteinModelPortal Q155Q3
SMR Q155Q3
BioGrid 124542
IntAct Q155Q3
MINT MINT-8080298
STRING 9606.ENSP00000394352
PhosphoSite Q155Q3
DMDM 147641721
MaxQB Q155Q3
PaxDb Q155Q3
PRIDE Q155Q3
Ensembl ENST00000440460
ENST00000529225
ENST00000615255
GeneID 85458
KEGG hsa:85458
UCSC uc001pmk.3
uc001pml.3
uc001pmm.3
CTD 85458
GeneCards GC11P111797
HGNC HGNC:23695
HPA HPA039424
HPA039658
MIM 610493
neXtProt NX_Q155Q3
PharmGKB PA134988674
eggNOG NOG150719
GeneTree ENSGT00390000013552
HOVERGEN HBG107812
InParanoid Q155Q3
OMA RDWRPGS
PhylomeDB Q155Q3
ChiTaRS DIXDC1
GeneWiki DIXDC1
GenomeRNAi 85458
NextBio 35504789
PRO PR:Q155Q3
Proteomes UP000005640
Bgee Q155Q3
CleanEx HS_DIXDC1
ExpressionAtlas Q155Q3
Genevestigator Q155Q3
GO GO:0043679
GO:0005938
GO:0005829
GO:0005925
GO:0043025
GO:0043015
GO:0031435
GO:0043010
GO:0021695
GO:0030900
GO:0050772
GO:0090263
GO:0046328
GO:0016055
Gene3D 1.10.418.10
InterPro IPR029800
IPR001715
IPR001158
IPR015506
IPR029071
PANTHER PTHR10878
PTHR10878:SF18
Pfam PF00307
PF00778
SMART SM00033
SUPFAM SSF47576
SSF54236
PROSITE PS50021
PS50841

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0060070

canonical Wnt signaling pathway

PMID:21189423[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0043015

gamma-tubulin binding

PMID:19375513[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:19375513[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0060070

canonical Wnt signaling pathway

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000499
MGI:MGI:106613
MGI:MGI:108100
MGI:MGI:2679721
MGI:MGI:94941
PANTHER:PTN000093945
UniProtKB:O14640
UniProtKB:O14641
UniProtKB:Q92997
ZFIN:ZDB-GENE-030721-2

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106613
PANTHER:PTN000093945
UniProtKB:Q155Q3
UniProtKB:Q92997

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0070507

regulation of microtubule cytoskeleton organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0060070

canonical Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0045665

negative regulation of neuron differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0032956

regulation of actin cytoskeleton organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0030177

positive regulation of Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0021869

forebrain ventricular zone progenitor cell division

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0021846

cell proliferation in forebrain

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0021799

cerebral cortex radially oriented cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

involved_in

GO:0021795

cerebral cortex cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

P

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80Y83
ensembl:ENSMUSP00000034566

F

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015506

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0118

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Liu, YT et al. (2011) Molecular basis of Wnt activation via the DIX domain protein Ccd1. J. Biol. Chem. 286 8597-608 PubMed GONUTS page
  2. 2.0 2.1 Wu, Y et al. (2009) DIXDC1 co-localizes and interacts with gamma-tubulin in HEK293 cells. Cell Biol. Int. 33 697-701 PubMed GONUTS page
  3. 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page