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HUMAN:DAND5
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | DAND5 (synonyms: CER2, CKTSF1B3, GREM3, SP1) | |
Protein Name(s) | DAN domain family member 5
Cerberus-like protein 2 Cerl-2 Cysteine knot superfamily 1, BMP antagonist 3 Gremlin-3 | |
External Links | ||
UniProt | Q8N907 | |
EMBL | AB070695 AK095926 BC101800 BC113476 | |
CCDS | CCDS12291.1 | |
RefSeq | NP_689867.1 | |
UniGene | Hs.331981 | |
ProteinModelPortal | Q8N907 | |
SMR | Q8N907 | |
STRING | 9606.ENSP00000323155 | |
DMDM | 74729571 | |
MaxQB | Q8N907 | |
PaxDb | Q8N907 | |
PRIDE | Q8N907 | |
Ensembl | ENST00000317060 | |
GeneID | 199699 | |
KEGG | hsa:199699 | |
UCSC | uc002mwc.1 | |
CTD | 199699 | |
GeneCards | GC19P013081 | |
HGNC | HGNC:26780 | |
HPA | HPA049472 | |
MIM | 609068 | |
neXtProt | NX_Q8N907 | |
PharmGKB | PA134875268 | |
eggNOG | NOG38827 | |
GeneTree | ENSGT00530000063926 | |
HOGENOM | HOG000112140 | |
HOVERGEN | HBG094958 | |
InParanoid | Q8N907 | |
OMA | RNHLCFG | |
PhylomeDB | Q8N907 | |
TreeFam | TF106445 | |
SignaLink | Q8N907 | |
GenomeRNAi | 199699 | |
NextBio | 89693 | |
PRO | PR:Q8N907 | |
Proteomes | UP000005640 | |
Bgee | Q8N907 | |
CleanEx | HS_DAND5 HS_SP1 | |
ExpressionAtlas | Q8N907 | |
Genevestigator | Q8N907 | |
GO | GO:0005576 GO:0016015 GO:0003283 GO:0061371 GO:0003140 GO:0030514 GO:1900108 GO:0030512 GO:0038101 GO:0003281 | |
InterPro | IPR016860 IPR004133 | |
Pfam | PF03045 | |
PIRSF | PIRSF027807 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:1900108 |
negative regulation of nodal signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0061371 |
determination of heart left/right asymmetry |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0038101 |
sequestering of nodal from receptor via nodal binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030514 |
negative regulation of BMP signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016015 |
morphogen activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0003283 |
atrial septum development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0003281 |
ventricular septum development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0003140 |
determination of left/right asymmetry in lateral mesoderm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1900176 |
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000392278 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061371 |
determination of heart left/right asymmetry |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1344365 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035582 |
sequestering of BMP in extracellular matrix |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1201414 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0023019 |
signal transduction involved in regulation of gene expression |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1201414 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0016015 |
morphogen activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1344365 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1201414 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016015 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016015 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016015 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1900108 |
negative regulation of nodal signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061371 |
determination of heart left/right asymmetry |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0038101 |
sequestering of nodal from receptor via nodal binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030514 |
negative regulation of BMP signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0017015 |
regulation of transforming growth factor beta receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0016015 |
morphogen activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007368 |
determination of left/right symmetry |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0003283 |
atrial septum development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0003281 |
ventricular septum development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0003140 |
determination of left/right asymmetry in lateral mesoderm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q76LW6 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Marques, S et al. (2004) The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev. 18 2342-7 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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