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HUMAN:BOREA

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) CDCA8 (synonyms: PESCRG3)
Protein Name(s) Borealin

Cell division cycle-associated protein 8 Dasra-B hDasra-B Pluripotent embryonic stem cell-related gene 3 protein

External Links
UniProt Q53HL2
EMBL BG354581
AY508815
AK001330
AK022104
AK022606
AK222549
AK222568
CH471059
CH471059
BC000703
BC001651
BC016944
BC008079
CCDS CCDS424.1
RefSeq NP_001243804.1
NP_060571.1
UniGene Hs.524571
PDB 2KDD
2QFA
2RAW
2RAX
PDBsum 2KDD
2QFA
2RAW
2RAX
ProteinModelPortal Q53HL2
SMR Q53HL2
BioGrid 120446
DIP DIP-37995N
IntAct Q53HL2
MINT MINT-4509527
STRING 9606.ENSP00000316121
PhosphoSite Q53HL2
DMDM 110832774
MaxQB Q53HL2
PaxDb Q53HL2
PeptideAtlas Q53HL2
PRIDE Q53HL2
DNASU 55143
Ensembl ENST00000327331
ENST00000373055
GeneID 55143
KEGG hsa:55143
UCSC uc001cbr.4
CTD 55143
GeneCards GC01P038158
HGNC HGNC:14629
HPA CAB040294
HPA028120
HPA028258
HPA028783
MIM 609977
neXtProt NX_Q53HL2
PharmGKB PA26281
eggNOG NOG39975
GeneTree ENSGT00390000011115
HOGENOM HOG000261628
HOVERGEN HBG080103
InParanoid Q53HL2
KO K11514
OMA QIESDRQ
OrthoDB EOG7ZPNKN
PhylomeDB Q53HL2
TreeFam TF101077
Reactome REACT_150425
REACT_150471
REACT_682
ChiTaRS CDCA8
EvolutionaryTrace Q53HL2
GeneWiki CDCA8
GenomeRNAi 55143
NextBio 58844
PRO PR:Q53HL2
Proteomes UP000005640
Bgee Q53HL2
CleanEx HS_CDCA8
Genevestigator Q53HL2
GO GO:0010369
GO:0032133
GO:0000775
GO:0005829
GO:0045171
GO:0030496
GO:0005730
GO:0005634
GO:0043234
GO:0005819
GO:0051301
GO:0051276
GO:0000278
GO:0007080
InterPro IPR018851
IPR018867
Pfam PF10512
PF10444

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0051276

chromosome organization

PMID:15260989[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

PMID:16239925[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032133

chromosome passenger complex

PMID:18591255[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O15392

C

Seeded From UniProt

complete

part_of

GO:0032133

chromosome passenger complex

PMID:15260989[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O15392

C

Seeded From UniProt

complete

part_of

GO:0032133

chromosome passenger complex

PMID:15260989[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q96GD4

C

Seeded From UniProt

complete

part_of

GO:0000775

chromosome, centromeric region

PMID:15260989[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007080

mitotic metaphase plate congression

PMID:15260989[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0051233

spindle midzone

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0032105
PANTHER:PTN001815752

C

Seeded From UniProt

complete

part_of

GO:0032133

chromosome passenger complex

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0032104
FB:FBgn0032105
PANTHER:PTN001815752
PomBase:SPBC725.12
UniProtKB:Q53HL2

C

Seeded From UniProt

complete

part_of

GO:0000775

chromosome, centromeric region

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001815752
UniProtKB:Q53HL2

C

Seeded From UniProt

complete

involved_in

GO:0000070

mitotic sister chromatid segregation

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001815752
PomBase:SPBC725.12

P

Seeded From UniProt

complete

part_of

GO:0045171

intercellular bridge

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030496

midbody

PMID:22724069[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0010369

chromocenter

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BHX3
ensembl:ENSMUSP00000081319

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-5666169
Reactome:R-HSA-5666160
Reactome:R-HSA-5666129
Reactome:R-HSA-4655355
Reactome:R-HSA-375302
Reactome:R-HSA-2484822
Reactome:R-HSA-2468287
Reactome:R-HSA-2467811
Reactome:R-HSA-2467809
Reactome:R-HSA-1638821
Reactome:R-HSA-1638803
Reactome:R-HSA-141439
Reactome:R-HSA-141431
Reactome:R-HSA-141422
Reactome:R-HSA-141409

ECO:0000304

author statement supported by traceable reference used in manual assertion















C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-4655355

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

part_of

GO:0000775

chromosome, centromeric region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0137
UniProtKB-SubCell:SL-0047

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005694

chromosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0158

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0132

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0188

C

Seeded From UniProt

complete

part_of

GO:0005819

spindle

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0251

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Sampath, SC et al. (2004) The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly. Cell 118 187-202 PubMed GONUTS page
  2. ↑ Vader, G et al. (2006) Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody. EMBO Rep. 7 85-92 PubMed GONUTS page
  3. ↑ Xia, F et al. (2008) A survivin-ran complex regulates spindle formation in tumor cells. Mol. Cell. Biol. 28 5299-311 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  5. ↑ Capalbo, L et al. (2012) The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis. Open Biol 2 120070 PubMed GONUTS page
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