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ECOLX:PARM
Contents
| Species (Taxon ID) | Escherichia coli. (562) | |
| Gene Name(s) | parM (synonyms: stbA) | |
| Protein Name(s) | Plasmid segregation protein ParM
ParA locus 36 kDa protein Protein StbA | |
| External Links | ||
| UniProt | P11904 | |
| EMBL | X12777 X04268 | |
| PIR | A24920 | |
| RefSeq | NP_957570.1 WP_000959884.1 YP_001096425.1 YP_002456142.1 YP_003108258.1 YP_006953486.1 YP_006953911.1 YP_006954241.1 YP_006990723.1 YP_007447518.1 YP_008531404.1 YP_009068579.1 YP_009073917.1 YP_009074372.1 | |
| PDB | 1MWK 1MWM 2QU4 2ZGY 2ZGZ 2ZHC 3IKU 3IKY 4A61 4A62 4A6J 5AEY 5AI7 | |
| PDBsum | 1MWK 1MWM 2QU4 2ZGY 2ZGZ 2ZHC 3IKU 3IKY 4A61 4A62 4A6J 5AEY 5AI7 | |
| ProteinModelPortal | P11904 | |
| SMR | P11904 | |
| DIP | DIP-29623N | |
| PRIDE | P11904 | |
| GeneID | 13906411 13906847 13906930 13982300 14612532 16833925 20491711 2716545 4924750 7256899 8319203 | |
| KEGG | pg:13906411 pg:13906847 pg:13906930 pg:13982300 pg:14612532 pg:16833925 pg:20491711 pg:2716545 pg:4924750 pg:7256899 pg:8319203 | |
| KO | K18640 | |
| EvolutionaryTrace | P11904 | |
| GO | GO:0030541 | |
| InterPro | IPR009440 | |
| Pfam | PF06406 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0030541 |
plasmid partitioning |
ECO:0000315 |
P |
ParM is an actin-like protein which generates dynamic filaments that are necessary for Plasmid DNA segregation. The filament polymerization is activated only with the presence of ATP-bound form of ParM protein (PMID:20550930[2]). Using the combined phase-contrast and immunofluorescence microscopy, figure 2C demonstrates the cells with mutation of ParM proteins fail to bind and hydrolyse ATP, leading to incorrect segregation of plasmid DNA. |
complete | |||||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030541 |
plasmid partitioning |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Møller-Jensen, J et al. (2002) Prokaryotic DNA segregation by an actin-like filament. EMBO J. 21 3119-27 PubMed GONUTS page
- ↑ Gerdes, K et al. (2010) Pushing and pulling in prokaryotic DNA segregation. Cell 141 927-42 PubMed GONUTS page
- ↑ Bharat, TA et al. (2015) Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles. Nature 523 106-10 PubMed GONUTS page
- ↑ Galkin, VE et al. (2009) Structural polymorphism of the ParM filament and dynamic instability. Structure 17 1253-64 PubMed GONUTS page
- ↑ Orlova, A et al. (2007) The structure of bacterial ParM filaments. Nat. Struct. Mol. Biol. 14 921-6 PubMed GONUTS page
