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ECOLI:SYI
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | ileS (synonyms: ilvS) | |
| Protein Name(s) | Isoleucine--tRNA ligase
Isoleucyl-tRNA synthetase IleRS | |
| External Links | ||
| UniProt | P00956 | |
| EMBL | U00096 AP009048 M10428 X00776 K01990 | |
| PIR | B64723 | |
| RefSeq | NP_414567.1 YP_488332.1 | |
| ProteinModelPortal | P00956 | |
| SMR | P00956 | |
| BioGrid | 849163 | |
| DIP | DIP-10017N | |
| IntAct | P00956 | |
| MINT | MINT-1232480 | |
| STRING | 511145.b0026 | |
| BindingDB | P00956 | |
| ChEMBL | CHEMBL3657 | |
| PaxDb | P00956 | |
| PRIDE | P00956 | |
| EnsemblBacteria | AAC73137 BAB96595 | |
| GeneID | 12932381 944761 | |
| KEGG | ecj:Y75_p0026 eco:b0026 | |
| PATRIC | 32115143 | |
| EchoBASE | EB0487 | |
| EcoGene | EG10492 | |
| eggNOG | COG0060 | |
| HOGENOM | HOG000246402 | |
| InParanoid | P00956 | |
| KO | K01870 | |
| OMA | VLGDWDN | |
| OrthoDB | EOG644ZM1 | |
| PhylomeDB | P00956 | |
| BioCyc | EcoCyc:ILES-MONOMER ECOL316407:JW0024-MONOMER MetaCyc:ILES-MONOMER | |
| PRO | PR:P00956 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P00956 | |
| GO | GO:0005737 GO:0002161 GO:0005524 GO:0004822 GO:0008270 GO:0006428 GO:0046677 | |
| Gene3D | 1.10.730.10 3.40.50.620 3.90.740.10 | |
| HAMAP | MF_02002 | |
| InterPro | IPR001412 IPR002300 IPR002301 IPR023585 IPR013155 IPR014729 IPR009080 IPR009008 IPR010663 | |
| PANTHER | PTHR11946:SF9 | |
| Pfam | PF08264 PF00133 PF06827 | |
| PRINTS | PR00984 | |
| SUPFAM | SSF47323 SSF50677 | |
| TIGRFAMs | TIGR00392 | |
| PROSITE | PS00178 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0004822 |
isoleucine-tRNA ligase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006428 |
isoleucyl-tRNA aminoacylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10492 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10492 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004822 |
isoleucine-tRNA ligase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10492 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006428 |
isoleucyl-tRNA aminoacylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004822 |
isoleucine-tRNA ligase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0106074 |
aminoacyl-tRNA metabolism involved in translational fidelity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0002161 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000049 |
tRNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001412 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0002161 |
aminoacyl-tRNA editing activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004812 |
aminoacyl-tRNA ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001412 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004822 |
isoleucine-tRNA ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001412 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006418 |
tRNA aminoacylation for protein translation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001412 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006428 |
isoleucyl-tRNA aminoacylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004822 |
isoleucine-tRNA ligase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000090066 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006428 |
isoleucyl-tRNA aminoacylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000090066 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004822 |
isoleucine-tRNA ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000090066 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000090066 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000090066 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006412 |
translation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004812 |
aminoacyl-tRNA ligase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Dureković, A et al. (1973) Isolation and properties of isoleucyl-tRNA synthetase from Escherichia coli MRE 600. Eur. J. Biochem. 36 528-33 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Xu, B et al. (1994) Probing the metal binding sites of Escherichia coli isoleucyl-tRNA synthetase. Biochemistry 33 398-402 PubMed GONUTS page
- ↑ 4.0 4.1 Fersht, AR & Kaethner, MM (1976) Mechanism of aminoacylation of tRNA. Proof of the aminoacyl adenylate pathway for the isoleucyl- and tyrosyl-tRNA synthetases from Escherichia coli K12. Biochemistry 15 818-23 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
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