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ECOLI:PURU
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | purU (ECO:0000255 with HAMAP-Rule:MF_01927) (synonyms: tgs, ychI) | |
| Protein Name(s) | Formyltetrahydrofolate deformylase (ECO:0000255 with HAMAP-Rule:MF_01927)
Formyl-FH(4) hydrolase (ECO:0000255 with HAMAP-Rule:MF_01927) | |
| External Links | ||
| UniProt | P37051 | |
| EMBL | L20251 M64675 U00096 AP009048 | |
| PIR | C36871 | |
| RefSeq | NP_415748.1 YP_489500.1 | |
| ProteinModelPortal | P37051 | |
| SMR | P37051 | |
| IntAct | P37051 | |
| STRING | 511145.b1232 | |
| PaxDb | P37051 | |
| PRIDE | P37051 | |
| DNASU | 945827 | |
| EnsemblBacteria | AAC74314 BAA36100 | |
| GeneID | 12932930 945827 | |
| KEGG | ecj:Y75_p1205 eco:b1232 | |
| PATRIC | 32117720 | |
| EchoBASE | EB1766 | |
| EcoGene | EG11819 | |
| eggNOG | COG0788 | |
| HOGENOM | HOG000033576 | |
| InParanoid | P37051 | |
| KO | K01433 | |
| OMA | IAQIDQY | |
| OrthoDB | EOG615VP4 | |
| PhylomeDB | P37051 | |
| BioCyc | EcoCyc:FORMYLTHFDEFORMYL-MONOMER ECOL316407:JW1220-MONOMER MetaCyc:FORMYLTHFDEFORMYL-MONOMER | |
| UniPathway | UPA00074 | |
| PRO | PR:P37051 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P37051 | |
| GO | GO:0016597 GO:0008864 GO:0016742 GO:0006189 GO:0009257 GO:0006730 GO:0006164 GO:0009152 | |
| Gene3D | 3.40.50.170 | |
| HAMAP | MF_01927 | |
| InterPro | IPR002912 IPR002376 IPR004810 | |
| PANTHER | PTHR10520:SF7 | |
| Pfam | PF01842 PF00551 | |
| PIRSF | PIRSF036480 | |
| PRINTS | PR01575 | |
| SUPFAM | SSF53328 | |
| TIGRFAMs | TIGR00655 | |
| PROSITE | PS51671 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006164 |
purine nucleotide biosynthetic process |
ECO:0000315 |
P |
Table 2. Mutants of the purU gene, along with the wild-type strains of E.coli were grown on medium containing various amino acids. Mutants required purine or formate supplementation for growth indicating role of purU in de novo purine nucleotide biosynthesis. |
complete | |||||
|
involved_in |
GO:0006164 |
purine nucleotide biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009152 |
purine ribonucleotide biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008864 |
formyltetrahydrofolate deformylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006189 |
'de novo' IMP biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008864 |
formyltetrahydrofolate deformylase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009058 |
biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016742 |
hydroxymethyl-, formyl- and related transferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008864 |
formyltetrahydrofolate deformylase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008864 |
formyltetrahydrofolate deformylase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161596 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006189 |
'de novo' IMP biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161596 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009257 |
10-formyltetrahydrofolate biosynthetic process |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006730 |
one-carbon metabolic process |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006164 |
purine nucleotide biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006730 |
one-carbon metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006189 |
'de novo' IMP biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00074 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Nagy, PL et al. (1993) purU, a source of formate for purT-dependent phosphoribosyl-N-formylglycinamide synthesis. J. Bacteriol. 175 7066-73 PubMed GONUTS page
- ↑ 2.0 2.1 Nagy, PL et al. (1995) Formyltetrahydrofolate hydrolase, a regulatory enzyme that functions to balance pools of tetrahydrofolate and one-carbon tetrahydrofolate adducts in Escherichia coli. J. Bacteriol. 177 1292-8 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ 4.0 4.1 de Crécy-Lagard, V et al. (2007) Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations. BMC Genomics 8 245 PubMed GONUTS page
