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ECOLI:PRIA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | priA (ECO:0000255 with HAMAP-Rule:MF_00983) | |
| Protein Name(s) | Primosomal protein N' (ECO:0000255 with HAMAP-Rule:MF_00983)
ATP-dependent helicase PriA (ECO:0000255 with HAMAP-Rule:MF_00983) Replication factor Y | |
| External Links | ||
| UniProt | P17888 | |
| EMBL | M33293 D00616 L19201 U00096 AP009048 | |
| PIR | S40878 | |
| RefSeq | NP_418370.1 YP_491516.1 | |
| PDB | 2D7E 2D7G 2D7H 2DWL 2DWM 2DWN | |
| PDBsum | 2D7E 2D7G 2D7H 2DWL 2DWM 2DWN | |
| ProteinModelPortal | P17888 | |
| SMR | P17888 | |
| DIP | DIP-10562N | |
| IntAct | P17888 | |
| MINT | MINT-1274231 | |
| STRING | 511145.b3935 | |
| EnsemblBacteria | AAC76917 BAE77375 | |
| GeneID | 12933657 948426 | |
| KEGG | ecj:Y75_p3252 eco:b3935 | |
| PATRIC | 32123387 | |
| EchoBASE | EB0756 | |
| EcoGene | EG10763 | |
| eggNOG | COG1198 | |
| HOGENOM | HOG000037413 | |
| InParanoid | P17888 | |
| KO | K04066 | |
| OMA | QRFNAPV | |
| OrthoDB | EOG6KT2K4 | |
| PhylomeDB | P17888 | |
| BioCyc | EcoCyc:EG10763-MONOMER ECOL316407:JW3906-MONOMER MetaCyc:EG10763-MONOMER | |
| EvolutionaryTrace | P17888 | |
| PRO | PR:P17888 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P17888 | |
| GO | GO:1990077 GO:0005524 GO:0043140 GO:0003677 GO:0004386 GO:0046872 GO:0006310 GO:0006260 GO:0006270 GO:0006269 GO:0006268 GO:0006261 GO:0006302 GO:0006276 GO:0046677 GO:0010332 | |
| Gene3D | 3.40.50.300 | |
| HAMAP | MF_00983 | |
| InterPro | IPR011545 IPR014001 IPR001650 IPR027417 IPR005259 | |
| Pfam | PF00270 PF00271 | |
| SMART | SM00487 SM00490 | |
| SUPFAM | SSF52540 | |
| TIGRFAMs | TIGR00595 | |
| PROSITE | PS51192 PS51194 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0043234 |
protein complex |
ECO:0000021 |
UniProtKB:P0AEF0 UniProtKB:P07013 UniProtKB:P0A8J2 UniProtKB:P0ACB0
|
C |
Figure 6 |
complete | ||||
| GO:0006261 |
DNA-dependent DNA replication |
ECO:0000314 |
P |
Table 1 |
complete | |||||
|
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10763 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10763 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006302 |
double-strand break repair |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10763 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006270 |
DNA replication initiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10763 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10763 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010332 |
response to gamma radiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006302 |
double-strand break repair |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006261 |
DNA-dependent DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006276 |
plasmid maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006270 |
DNA replication initiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004386 |
helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000165711 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000165711 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000165711 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000165711 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000165711 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:1990077 |
primosome complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000165711 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006269 |
DNA replication, synthesis of RNA primer |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004386 |
helicase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:1990077 |
primosome complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ng, JY & Marians, KJ (1996) The ordered assembly of the phiX174-type primosome. I. Isolation and identification of intermediate protein-DNA complexes. J. Biol. Chem. 271 15642-8 PubMed GONUTS page
- ↑ Wickner, S & Hurwitz, J (1974) Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. Proc. Natl. Acad. Sci. U.S.A. 71 4120-4 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Kogoma, T et al. (1996) The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair. J. Bacteriol. 178 1258-64 PubMed GONUTS page
- ↑ Liu, J et al. (1999) Replication fork assembly at recombination intermediates is required for bacterial growth. Proc. Natl. Acad. Sci. U.S.A. 96 3552-5 PubMed GONUTS page
- ↑ Lee, MS & Marians, KJ (1990) Differential ATP requirements distinguish the DNA translocation and DNA unwinding activities of the Escherichia coli PRI A protein. J. Biol. Chem. 265 17078-83 PubMed GONUTS page
- ↑ Lee, EH & Kornberg, A (1991) Replication deficiencies in priA mutants of Escherichia coli lacking the primosomal replication n' protein. Proc. Natl. Acad. Sci. U.S.A. 88 3029-32 PubMed GONUTS page
- ↑ Masai, H et al. (1994) Escherichia coli PriA protein is essential for inducible and constitutive stable DNA replication. EMBO J. 13 5338-45 PubMed GONUTS page
- ↑ 9.0 9.1 Lee, MS & Marians, KJ (1987) Escherichia coli replication factor Y, a component of the primosome, can act as a DNA helicase. Proc. Natl. Acad. Sci. U.S.A. 84 8345-9 PubMed GONUTS page
- ↑ Rangarajan, S et al. (2002) Replication restart in UV-irradiated Escherichia coli involving pols II, III, V, PriA, RecA and RecFOR proteins. Mol. Microbiol. 43 617-28 PubMed GONUTS page
a
b
d
- GO:0006261 ! DNA-templated DNA replication
- GO:0003677 ! DNA binding
- GO:0032508 ! DNA duplex unwinding
- GO:0006310 ! DNA recombination
- GO:0006270 ! DNA replication initiation
- GO:0006260 ! DNA replication
- GO:0006269 ! DNA replication, synthesis of primer
- GO:0006268 ! DNA unwinding involved in DNA replication
- GO:0006302 ! double-strand break repair
p
