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DROME:RCOR
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | CoRest | |
| Protein Name(s) | REST corepressor
CoREST | |
| External Links | ||
| UniProt | Q59E36 | |
| EMBL | AE014298 AE014298 AE014298 AE014298 AE014298 BT023817 AY060226 AY118507 | |
| RefSeq | NP_001014752.2 NP_001014753.1 NP_001014754.1 NP_001014755.1 NP_001014756.1 | |
| UniGene | Dm.4085 | |
| ProteinModelPortal | Q59E36 | |
| SMR | Q59E36 | |
| BioGrid | 59243 | |
| IntAct | Q59E36 | |
| MINT | MINT-1651349 | |
| PaxDb | Q59E36 | |
| PRIDE | Q59E36 | |
| GeneID | 32941 | |
| KEGG | dme:Dmel_CG42687 | |
| UCSC | CG33525-RA | |
| CTD | 32941 | |
| FlyBase | FBgn0261573 | |
| eggNOG | NOG326181 | |
| InParanoid | Q59E36 | |
| OrthoDB | EOG7MWGX1 | |
| GenomeRNAi | 32941 | |
| NextBio | 781152 | |
| Proteomes | UP000000803 | |
| GO | GO:0005634 GO:0017053 GO:0003682 GO:0003677 GO:0003714 GO:0016568 GO:0061086 GO:2000619 GO:0045892 GO:0045747 GO:0007221 GO:0006351 | |
| InterPro | IPR000949 IPR009057 IPR001005 IPR017884 | |
| Pfam | PF01448 | |
| SMART | SM00717 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS51156 PS51293 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0044212 |
transcription regulatory region DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001043031 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0017053 |
transcriptional repressor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261573 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008134 |
transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001043031 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1859854 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261573 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261573 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1859854 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090309 |
positive regulation of methylation-dependent chromatin silencing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061086 |
negative regulation of histone H3-K27 methylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000619 |
negative regulation of histone H4-K16 acetylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0017053 |
transcriptional repressor complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0260397 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
HGNC:17441 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0017053 |
transcriptional repressor complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0015805 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003682 |
chromatin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006325 |
chromatin organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Yu, Y et al. (2015) Panoramix enforces piRNA-dependent cotranscriptional silencing. Science 350 339-42 PubMed GONUTS page
- ↑ 3.0 3.1 Domanitskaya, E & Schüpbach, T (2012) CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster. J. Cell. Sci. 125 399-410 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Dallman, JE et al. (2004) A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation. J. Neurosci. 24 7186-93 PubMed GONUTS page
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